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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of a fiber optic high dynamic range magnetic field gradiometer operable in unshielded environments

    SBC: TIPD LLC            Topic: SB161005

    Proposed, is a low cost fiber optic high dynamic range magnetic field gradient measurement system for noninvasive, real-time monitoring of bio-magnetic activities with high spatiotemporal resolution in unshielded environment. Each gradient measurement system would consist of 1 scalar magnetometer, 1 each of horizontal and vertical gradiometers, and additional scalar magnetometers for background ma ...

    SBIR Phase I 2016 Department of DefenseDefense Advanced Research Projects Agency
  2. A High Resolution Radiation Therapy Dosimetry system

    SBC: DOSEIMAGING, LLC            Topic: 399

    DESCRIPTION provided by applicant Modern radiation therapy treatment modalities such as intensity modulated radiation therapy are associated with complex dose distributions and sharp dose gradients Experimental dose validation using multidimensional high spatial resolution dosimeters is mandatory The product to be developed is a novel high resolution dosimetry system that combines reusabil ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. PEGYLATED PEPTIDES LIGANDS TARGETING RADIATION-INDUCIBLE RECEPTORS ON CANCER

    SBC: Medical Guidance Systems LLC            Topic: 102

    DESCRIPTION provided by applicant The proposed research is the study of new paradigms in both the treatment of cancer and cancer drug development This platform technology will markedly expand the number of cancer specific surface receptors and antigens that can be targeted for drug delivery using peptide ligands The general principle of this new technology is that cancer cells respond to ioni ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Dual-view endoscopic probe

    SBC: Omniscient Imaging, Inc.            Topic: 102

    DESCRIPTION provided by applicant Colon cancer is a leading cause of cancer death in the United States and overseas Colonoscopy is the preferred screening method at an estimated annual cost of over $ billion in the US Unfortunately many lesions are missed because pre cancerous growths remain hidden from view behind folds and flexures of the colon Current methods of increasing the field of ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Pancreatic Ductal Adenocarcinoma Targeted Ultrasound Contrast Agent Development

    SBC: NUVOX PHARMA, L.L.C.            Topic: 394

    DESCRIPTION provided by applicant Pancreatic ductal adenocarcinoma PDAC is a deadly form of cancer and patient survival depends upon the stage of diagnosis While overall survival at diagnosis is only about months of patients with stage I disease survive years The best currently available diagnostic test which is routinely performed in patients at high risk for PDAC is endoscop ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Carbon Fiber Off-Loading Orthosis

    SBC: Orthotic & Prosthetic Design, Inc.            Topic: 200

    DESCRIPTION provided by applicant This proposed project will further develop a CFC off loading AFO designed to offload plantar pressures and optimize patient function through maximizing plantarflexor power production During Phase I we will determine the effects of varying design characteristics of CFC off loading AFOs We will refine and create new FEA models and algorithms that predict the ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Preclinical Testing of Tetrandrine against Noise-Induce Hearing Loss

    SBC: GATEWAY BIOTECHNOLOGY, INC.            Topic: R

    DESCRIPTION provided by applicant Noise is the most common occupational and environmental hazard thus it is not surprising that noise induced hearing loss NIHL is the second most common form of sensorineural hearing deficit second only to age related hearing loss Although therapeutics that target the free radical pathway have shown promise for reducing NIHL there are no medications approv ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Single-Molecule Analyte Detection by Molecular Motor-driven Nanodevices

    SBC: Attometrics            Topic: NIGMS

    DESCRIPTION provided by applicant There is an urgent need for a platform technology that can monitor changes in metabolite and protein biomarkers below current detection limits because in many cases the disease has progressed to an advanced state by the time the abundance of the biomarker has become measurable Our molecular motor powered nanodevice linked immunosorbent assay MONA LISA is ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a Non adjuvanted VLP Vaccine against Stealth H N Influenza

    SBC: EPIVAX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. A robust heterologous expression system of intact fungal secondary metabolite gene clusters for natural product discovery in Aspergillus nidulans

    SBC: INTACT GENOMICS INC            Topic: R

    DESCRIPTION provided by applicant There is societal need for new therapeutic agents in our arsenal of defenses against bacterial and fungal pathogens many superbugs of which are increasingly resistant to existing antibiotics Filamentous fungi are considered promising resources for the development of novel bioactive compounds because of their great potential to produce various kinds of secon ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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