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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Development of a Non adjuvanted VLP Vaccine against Stealth H N Influenza

    SBC: EPIVAX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Goldmann Contact Tonometry with Optimized Error Correction

    SBC: INTUOR TECHNOLOGIES LLC            Topic: N

    DESCRIPTION provided by applicant Intraocular pressure IOP is arguably the second most important criteria used to assess visual acuity when eye care professionals are diagnosing treating and managing patients The patented Intuor Applanation Tonometer IAT prism design is a novel and simple approach for improving the accuracy of IOP measurement in the eye The proposal describes an inexpen ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Scalable amperometric microchip array for high throughput screening of small molecules peptides or genetic perturbations for modulation of quantal transmitter release

    SBC: EXOCYTRONICS, LLC            Topic: 101

    ` The goal of this project is the development of a scalable n x m electrochemical detector array platform with on chip amplifiers for massively parallel recordings of quantal transmitter release events The neurobiological process that this assay analyzes is the process of exocytosis and transmitter release Neurotransmitters and hormones are stored at high concentration in membrane bound organel ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Human Apyrase Therapy for Acute Ischemic Stroke

    SBC: APT THERAPEUTICS, INC.            Topic: 105

    Principal Investigator Program Director Last First Middle Chen Ridong Abstract There remains a crucial unmet medical need in acute ischemic stroke AIS treatment Approximately of patients die within one year and are permanently disabled making AIS the fourth leading cause of death and the leading cause of adult disability in the USA with an estimated cost range of $ ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Development of a fiber optic high dynamic range magnetic field gradiometer operable in unshielded environments

    SBC: TIPD, LLC            Topic: SB161005

    Proposed, is a low cost fiber optic high dynamic range magnetic field gradient measurement system for noninvasive, real-time monitoring of bio-magnetic activities with high spatiotemporal resolution in unshielded environment. Each gradient measurement system would consist of 1 scalar magnetometer, 1 each of horizontal and vertical gradiometers, and additional scalar magnetometers for background ma ...

    SBIR Phase I 2016 Department of DefenseDefense Advanced Research Projects Agency
  6. High-Sample Rate Analog to Digital Converters for Reconfigurable Phased Array Applications

    SBC: Alphacore, Inc.            Topic: SB153004

    This SBIR Phase I proposal requests support for Alphacore, Inc. to design and characterize a 40Gsps (giga-samples per-second), 7-bit (ENOB > 6 bits), low-power (

    SBIR Phase I 2016 Department of DefenseDefense Advanced Research Projects Agency
  7. Heterogeneous Porous Media for Thermal Transport Mitigation in Hypersonics

    SBC: S. D. MILLER AND ASSOCIATES P.L.L.C.            Topic: AF161005

    ABSTRACT: S. D. Miller and Associates (SDMA) research team has led the field of research in Opacified Fibrous Insulation (OFI) since 2003.Early OFI prototypes equaled the thermal performance of Thermal Protection Systems (TPS) with MultiLayer Insulation (MLI) using gold-coated shields and vastly reduced cost and maintenance of TPS for hypersonic vehicles.In 2015, OFI prototypes demonstrated improv ...

    SBIR Phase I 2016 Department of DefenseAir Force
  8. Prediction of Boundary Layer Transition on Hypersonic Vehicles in Large-Scale Wind Tunnels and Flight

    SBC: Arizona Engineering Science LLC            Topic: AF161024

    A comprehensive framework for hypersonic boundary layer transition predictions applicable to wind tunnel and free flight conditions is proposed. The distinguishing feature of this transition prediction framework is that it is developed from the ground up allowing full integration of the important transition regions (receptivity region, linear/secondary/nonlinear stability regimes, etc.) and additi ...

    SBIR Phase I 2016 Department of DefenseAir Force
  9. Uniformed Aeroelastic ROM Realization Across Flight Parameter Space for Dynamic Flight Simulation

    SBC: Zona Technology, Inc            Topic: AF161026

    ABSTRACT: The proposed effort will focus on the development of the parameterized Navier-Stokes (NS) based ROM for the Dynamic Flight Simulation (DFS) framework. The F/A-18 Active Aeroelastic Wing (AAW) aircraft will be used as the test case to investigate and validate the proposed methods.The background flow solutions under various Mach number and angle-of-attack grid points are first obtained by ...

    SBIR Phase I 2016 Department of DefenseAir Force
  10. Highly doped glass enabled high repetition rate, high average power USPL sources

    SBC: NP Photonics, Inc.            Topic: AF161038

    ABSTRACT: NP Photonics proposes to develop a high repetition rate, high average power USPL source by taking advantage of our laser technologies based on highly doped glasses. This USPL source has the advantages of high power scalability, compactness, and high reliability.In this Phase I program, we will investigate the feasibility and study the risk to develop a power scalable USPL using our highl ...

    SBIR Phase I 2016 Department of DefenseAir Force

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