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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Development of a Non adjuvanted VLP Vaccine against Stealth H N Influenza

    SBC: EPIVAX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Nanotechnology-Based Environmental Smart Sensors for Personal Health Exposure Monitoring

    SBC: Wi-Sense LLC            Topic: NIEHS

    DESCRIPTION provided by applicant A broad goal of the proposed research is to develop personal exposure monitors comprising wearable wireless sensor arrays to detect harmful air pollutants within the breathing zone and improve the assessment of causative exposure dose response relationships in epidemiological studies Heterogeneous orthogonal detectors comprising functionalized carbon nanotub ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Goldmann Contact Tonometry with Optimized Error Correction

    SBC: INTUOR TECHNOLOGIES LLC            Topic: N

    DESCRIPTION provided by applicant Intraocular pressure IOP is arguably the second most important criteria used to assess visual acuity when eye care professionals are diagnosing treating and managing patients The patented Intuor Applanation Tonometer IAT prism design is a novel and simple approach for improving the accuracy of IOP measurement in the eye The proposal describes an inexpen ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Microhook nerve tape A nerve repair coaptation aid

    SBC: Axion Biosystems, Inc.            Topic: 105

    DESCRIPTION provided by applicant This proposed project will develop and validate a microhook based nerve tape device for quick and effective repair of nerve injuries The microhook wrap consists of an array of microscale hooks distributed across a fine flexible meshwork and embedded in a biocompatible backing material This nerve tape will be used during nerve repair surgeries in place of mi ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Scalable amperometric microchip array for high throughput screening of small molecules peptides or genetic perturbations for modulation of quantal transmitter release

    SBC: EXOCYTRONICS, LLC            Topic: 101

    ` The goal of this project is the development of a scalable n x m electrochemical detector array platform with on chip amplifiers for massively parallel recordings of quantal transmitter release events The neurobiological process that this assay analyzes is the process of exocytosis and transmitter release Neurotransmitters and hormones are stored at high concentration in membrane bound organel ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Human Apyrase Therapy for Acute Ischemic Stroke

    SBC: APT THERAPEUTICS, INC.            Topic: 105

    Principal Investigator Program Director Last First Middle Chen Ridong Abstract There remains a crucial unmet medical need in acute ischemic stroke AIS treatment Approximately of patients die within one year and are permanently disabled making AIS the fourth leading cause of death and the leading cause of adult disability in the USA with an estimated cost range of $ ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a fiber optic high dynamic range magnetic field gradiometer operable in unshielded environments

    SBC: TIPD, LLC            Topic: SB161005

    Proposed, is a low cost fiber optic high dynamic range magnetic field gradient measurement system for noninvasive, real-time monitoring of bio-magnetic activities with high spatiotemporal resolution in unshielded environment. Each gradient measurement system would consist of 1 scalar magnetometer, 1 each of horizontal and vertical gradiometers, and additional scalar magnetometers for background ma ...

    SBIR Phase I 2016 Department of DefenseDefense Advanced Research Projects Agency
  8. Ultra-Low Power Physical Based Computation for Tactical Algorithm Design and Implementation

    SBC: Mavric Semiconductor Inc            Topic: ST15C002

    This proposal outlines an FPAA-based analog processing architecture that supports multi-chip module cascading, can be integrated into complex mixed analog-digital processing environments and can host sophisticated signal processing algorithms such as PDE-derived algorithms. The central innovation of the proposed effort lies in the physical device approach to embedded computing that breaks the ener ...

    SBIR Phase I 2016 Department of DefenseDefense Advanced Research Projects Agency
  9. Building Trustworthy Software Systems using Big Code

    SBC: American Software Safety Reliability Ltd.Co            Topic: SB161004

    On December 31, 2014, it was disclosed that the F-35 Joint Strike Fighter was unable to fire its guns due to a glitch in the software, delaying production of the aircraft until 2019. Current industry tools for ensuring software quality statically check the code for security and run-time vulnerabilities that are often the cause of failure in complex software systems. Unfortunately, these tools suff ...

    SBIR Phase I 2016 Department of DefenseDefense Advanced Research Projects Agency
  10. Persistent GEO Platform for Sustainable On-Orbit Capabilities

    SBC: SPACEWORKS ENGINEERING, INC.            Topic: SB161007

    SpaceWorks Enterprises, Inc. (SEI) seeks government support for the development of a sustainable and evolvable platform to provide persistent capabilities in GEO-space. As envisioned, this platform will enable a wealth of new capabilities at reduced cost compared to current systems and solutions.

    SBIR Phase I 2016 Department of DefenseDefense Advanced Research Projects Agency

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