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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Development of a fiber optic high dynamic range magnetic field gradiometer operable in unshielded environments
SBC: TIPD LLC Topic: SB161005Proposed, is a low cost fiber optic high dynamic range magnetic field gradient measurement system for noninvasive, real-time monitoring of bio-magnetic activities with high spatiotemporal resolution in unshielded environment. Each gradient measurement system would consist of 1 scalar magnetometer, 1 each of horizontal and vertical gradiometers, and additional scalar magnetometers for background ma ...
SBIR Phase I 2016 Department of DefenseDefense Advanced Research Projects Agency -
A High Resolution Radiation Therapy Dosimetry system
SBC: DOSEIMAGING, LLC Topic: 399DESCRIPTION provided by applicant Modern radiation therapy treatment modalities such as intensity modulated radiation therapy are associated with complex dose distributions and sharp dose gradients Experimental dose validation using multidimensional high spatial resolution dosimeters is mandatory The product to be developed is a novel high resolution dosimetry system that combines reusabil ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
PEGYLATED PEPTIDES LIGANDS TARGETING RADIATION-INDUCIBLE RECEPTORS ON CANCER
SBC: Medical Guidance Systems LLC Topic: 102DESCRIPTION provided by applicant The proposed research is the study of new paradigms in both the treatment of cancer and cancer drug development This platform technology will markedly expand the number of cancer specific surface receptors and antigens that can be targeted for drug delivery using peptide ligands The general principle of this new technology is that cancer cells respond to ioni ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Pancreatic Ductal Adenocarcinoma Targeted Ultrasound Contrast Agent Development
SBC: NUVOX PHARMA, L.L.C. Topic: 394DESCRIPTION provided by applicant Pancreatic ductal adenocarcinoma PDAC is a deadly form of cancer and patient survival depends upon the stage of diagnosis While overall survival at diagnosis is only about months of patients with stage I disease survive years The best currently available diagnostic test which is routinely performed in patients at high risk for PDAC is endoscop ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Development of a small molecule activator of integrin cell adhesion to enhance therapeutic responses to checkpoint blockade in cancer
SBC: 7 Hills Pharma LLC Topic: 102DESCRIPTION provided by applicant Recent FDA approvals of ipilimumab nivolumab and pembrolizumab which target checkpoint receptors cytotoxic T lymphocyte associated antigen CTLA and programmed death PD have ushered in a new era of cancer immunotherapy in metastatic melanoma Despite unprecedented overall survival benefits with combination therapy the incidence of complete respo ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Carbon Fiber Off-Loading Orthosis
SBC: Orthotic & Prosthetic Design, Inc. Topic: 200DESCRIPTION provided by applicant This proposed project will further develop a CFC off loading AFO designed to offload plantar pressures and optimize patient function through maximizing plantarflexor power production During Phase I we will determine the effects of varying design characteristics of CFC off loading AFOs We will refine and create new FEA models and algorithms that predict the ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Preclinical Testing of Tetrandrine against Noise-Induce Hearing Loss
SBC: GATEWAY BIOTECHNOLOGY, INC. Topic: RDESCRIPTION provided by applicant Noise is the most common occupational and environmental hazard thus it is not surprising that noise induced hearing loss NIHL is the second most common form of sensorineural hearing deficit second only to age related hearing loss Although therapeutics that target the free radical pathway have shown promise for reducing NIHL there are no medications approv ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Optimization of the Production and Isolation of the Novel Antifungal Occidiofungin
SBC: Sano Chemicals, Inc. Topic: NIAIDDESCRIPTION provided by applicant Occidiofungin is a cyclic nonribosomally synthesized antifungal peptide with submicromolar fungicidal activity against a broad spectrum of fungi Occidiofungin is produced by the Gram negative bacterium Burkholderia contaminans From our structural characterization studies occidiofungin was determined to have a unique chemical composition Our studies have als ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Single-Molecule Analyte Detection by Molecular Motor-driven Nanodevices
SBC: Attometrics Topic: NIGMSDESCRIPTION provided by applicant There is an urgent need for a platform technology that can monitor changes in metabolite and protein biomarkers below current detection limits because in many cases the disease has progressed to an advanced state by the time the abundance of the biomarker has become measurable Our molecular motor powered nanodevice linked immunosorbent assay MONA LISA is ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Digital Gene Expression Analysis by 3’ End Sequencing
SBC: BIOO SCIENTIFIC CORPORATION Topic: 172DESCRIPTION provided by applicant A key application of deep sequencing is gene expression analysis at the RNA level commonly known as RNA seq Reads from RNA seq cover all regions of an mRNA sequence However sequences derived from the andapos end region are sufficient to indicate gene expression levels All andapos end sequencing methods have revealed that most eukaryotic genes display a ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health