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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A High Resolution Radiation Therapy Dosimetry system

    SBC: DOSEIMAGING, LLC            Topic: 399

    DESCRIPTION provided by applicant Modern radiation therapy treatment modalities such as intensity modulated radiation therapy are associated with complex dose distributions and sharp dose gradients Experimental dose validation using multidimensional high spatial resolution dosimeters is mandatory The product to be developed is a novel high resolution dosimetry system that combines reusabil ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. PEGYLATED PEPTIDES LIGANDS TARGETING RADIATION-INDUCIBLE RECEPTORS ON CANCER

    SBC: Medical Guidance Systems LLC            Topic: 102

    DESCRIPTION provided by applicant The proposed research is the study of new paradigms in both the treatment of cancer and cancer drug development This platform technology will markedly expand the number of cancer specific surface receptors and antigens that can be targeted for drug delivery using peptide ligands The general principle of this new technology is that cancer cells respond to ioni ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Dual-view endoscopic probe

    SBC: Omniscient Imaging, Inc.            Topic: 102

    DESCRIPTION provided by applicant Colon cancer is a leading cause of cancer death in the United States and overseas Colonoscopy is the preferred screening method at an estimated annual cost of over $ billion in the US Unfortunately many lesions are missed because pre cancerous growths remain hidden from view behind folds and flexures of the colon Current methods of increasing the field of ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Pancreatic Ductal Adenocarcinoma Targeted Ultrasound Contrast Agent Development

    SBC: NUVOX PHARMA, L.L.C.            Topic: 394

    DESCRIPTION provided by applicant Pancreatic ductal adenocarcinoma PDAC is a deadly form of cancer and patient survival depends upon the stage of diagnosis While overall survival at diagnosis is only about months of patients with stage I disease survive years The best currently available diagnostic test which is routinely performed in patients at high risk for PDAC is endoscop ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Carbon Fiber Off-Loading Orthosis

    SBC: Orthotic & Prosthetic Design, Inc.            Topic: 200

    DESCRIPTION provided by applicant This proposed project will further develop a CFC off loading AFO designed to offload plantar pressures and optimize patient function through maximizing plantarflexor power production During Phase I we will determine the effects of varying design characteristics of CFC off loading AFOs We will refine and create new FEA models and algorithms that predict the ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Preclinical Testing of Tetrandrine against Noise-Induce Hearing Loss

    SBC: GATEWAY BIOTECHNOLOGY, INC.            Topic: R

    DESCRIPTION provided by applicant Noise is the most common occupational and environmental hazard thus it is not surprising that noise induced hearing loss NIHL is the second most common form of sensorineural hearing deficit second only to age related hearing loss Although therapeutics that target the free radical pathway have shown promise for reducing NIHL there are no medications approv ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Single-Molecule Analyte Detection by Molecular Motor-driven Nanodevices

    SBC: Attometrics            Topic: NIGMS

    DESCRIPTION provided by applicant There is an urgent need for a platform technology that can monitor changes in metabolite and protein biomarkers below current detection limits because in many cases the disease has progressed to an advanced state by the time the abundance of the biomarker has become measurable Our molecular motor powered nanodevice linked immunosorbent assay MONA LISA is ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Combinatorial Inactivation of ERBB Receptors in Breast Cancer using Therapeutic Stapled Peptides

    SBC: ARIZONA CANCER THERAPEUTICS L.L.C.            Topic: 103

    DESCRIPTION provided by applicant In metastatic breast cancer the Epidermal Growth Factor Receptor family of transmembrane tyrosine kinases ErbB drives proliferation and metastasis EGFR HER and ErbB are known to be highly expressed and active in both the HER and Triple Negative Basal subtypes of breast cancer and have been targeted with varying effectiveness Importantly targeting of ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Targeted and Non-targeted Microbubbles for Pediatric Applications

    SBC: NUVOX PHARMA, L.L.C.            Topic: NICHD

    Project Summary Staphylococcus is the most common cause of community and hospital acquired infective endocarditis worldwide Staphylococcal S aureus endocarditis is a serious health problem in children and adults that carries high morbidity and mortality The incidence of this disease is increasing due to healthcare advances with widespread use ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Ultrahigh Performance Non-Denaturing Protein Chromatography Columns

    SBC: BIOVIDRIA, INC.            Topic: 400

    PROJECT SUMMARY The proposed product is an analytical scale UHPLC column for separating protein drugs in native form with the Phase I proposal focused on anion exchange chromatography as the separation mechanism The bonded phase is made of polymer chains in this case bearing weak anion exchange groups The study will be expanded to cation exchange and hydrophobic interaction chromatography in ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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