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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Release Chondroitinase Systems for Spinal Cord Injury

    SBC: Acorda Therapeutics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Spinal cord injury (SCI) inflicts trauma to the cells and tissues of the central nervous system and causes a severe and debilitating condition in the individual. Following SCI, limited regeneration of injured neurons results in permanent disability characterized by some loss of sensation, paralysis and autonomic dysfunction. One reason that neurons fail to rege ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  2. Enhancing Elderly Balance & Gait Using Mechanical Noise

    SBC: AFFERENT CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): EIderly falls constitute one of the most costly health problems in the U.S., both in terms of expense to the healthcare system and in individual suffering. Fully one-third of people over age 65 fall each year, many incurring significant injuries that strongly impact their long-term health prospects and productivity. Although many factors contribute to the prop ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  3. Enhancing Elderly Balance & Gait Using Mechanical Noise

    SBC: AFFERENT CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): EIderly falls constitute one of the most costly health problems in the U.S., both in terms of expense to the healthcare system and in individual suffering. Fully one-third of people over age 65 fall each year, many incurring significant injuries that strongly impact their long-term health prospects and productivity. Although many factors contribute to the prop ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  4. Hydronic, High-Speed, Focal Thermal Stimulator

    SBC: ALA SCIENTIFIC INSTRUMENTS INC            Topic: N/A

    DESCRIPTION (provided by applicant): Cloning of the hot and cold thermal receptors has advanced the understanding of the molecular basis of thermal sensation. Two important remaining questions to be addressed are the identification of additional thermal receptor genes and the elucidation of the mechanism(s) that enable the receptor proteins to alter gating properties in response to changes in temp ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  5. Renal Injury Prevention by SF/HGF-like Small Molecules

    SBC: Angion Biomedica Corp.            Topic: N/A

    DESCRIPTION (provided by applicant): Chronic renal dysfunction is a progressive, degenerative disorder that ultimately results in acute renal failure and requires dialysis as an intervention, and renal transplantation as the only potential cure. Initiating conditions of renal dysfunction include ischemia, diabetes, underlying cardiovascular disease, or renal toxicity associated with certain chemo ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  6. Anti-apoptotic Mechanism of SF/HGF Mimetics

    SBC: Angion Biomedica Corp.            Topic: N/A

    DESCRIPTION (provided by applicant): Apoptotic cell loss triggered by ischemia-reperfusion plays a prominent role in delayed graft function and acute renal failure following kidney transplant. In experimental models of ischemia-reperfusion, treatment with scatter factor/hepatocyte growth factor reduced renal dysfunction and accelerated renal regeneration, in part by attenuating apoptotic cell deat ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  7. Hepatocyte Growth Factor Mimetic for Liver Fibrosis

    SBC: Angion Biomedica Corp.            Topic: N/A

    DESCRIPTION (provided by applicant): Hepatic fibrosis, a disease affecting tens of millions of patients worldwide, is the liver scarring response that occurs in response to chronic injury from viral hepatitis B or C, excessive alcohol use, and iron overload, and often leads to liver failure and death. Despite the availability of antiviral and other therapies, most are ineffective in treating the u ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  8. Protection from Atherosclerosis by c-Met Agonist

    SBC: Angion Biomedica Corp.            Topic: N/A

    DESCRIPTION (provided by applicant): Activation of cell death pathways leading to endothelial cell apoptosis and neointimal vascular smooth muscle cell hyperplasia is an initial trigger of the progression of atherosclerotic lesions. Because apoptosis is a highly regulated cellular process and mediates the development of atherosclerotic plaques, targeted inhibition of endothelial cell apoptosis is ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  9. Fabrication of Large-Area Distributed Electronic Modules

    SBC: Anvik Corporation            Topic: N/A

    How can one make a sensor that can make different types of measurements on a large area, on a shape that is not known a priori, that is lightweight, that is accurate with a fine resolution, while at the same time has the resolution and sensitivity of astand-alone instrument, and at an affordable cost?'This proposal will develop a process and a tool to answer this commonly asked question in militar ...

    SBIR Phase I 2003 Department of DefenseDefense Advanced Research Projects Agency
  10. Photoablation System to Make Microfluidic Structures

    SBC: Anvik Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): In this proposal, we present a program to develop a low-cost, high-resolution, high-throughput maskless photoablation system for fabrication of microfluidic structures to be used in Biochip devices. In Phase I of this proposal, we will develop the equipment design, specifically focusing on the selection and incorporation of the spatial light modulator into the ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
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