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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Analyzing Human Dimensions of Software Engineering Processes

    SBC: APPLIED VISIONS, INC.            Topic: SB172007

    The Secure Decisions team will conduct research to: 1) determine how human dimensions of software engineering (SE) processes influence software security and quality; and 2) develop mechanisms for measuring these relationships in both open source and closed (private) development environments. The human dimensions of interest are: characteristics and behaviors of developers and development teams; en ...

    SBIR Phase II 2019 Department of DefenseDefense Advanced Research Projects Agency
  2. Preclinical Development of Semisynthetic Saponin Immunological Adjuvant Titerquil-1055 in the Context of an Influenza Vaccine

    SBC: ADJUVANCE TECHNOLOGIES, INC.            Topic: NIAID

    Increasingly defined vaccines against infectious diseases are better tolerated but less immunogenicrequiring use of an immunological adjuvant for best effectAdjuvance s semi synthetic saponin adjuvant TiterQuilTQLhas shown remarkable efficacy with a variety of antigens with no detectable reactogenicityWhen combined withof the leading vaccines against influenzaFluzoneFluarix and Flublokstriking aug ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. A Liposomal Platform for Spontageous, Particleized Presentation of HIV Trimer Immunogens

    SBC: POP Biotechnologies Inc.            Topic: NIAID

    Over one million Americans andmillion people worldwide are infected with HIVmaking it one of the most pressing public health concerns of our timeUnfortunatelythere are no vaccines available and treatment requires lifelong anti retroviral therapiesThis proposal combines two technologies for the development of a vaccine against HIVEnva novel adjuvantspontaneous nanoliposome antigen particleizationSN ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. TOPIC 356: FLUOROGENIC ASSAY PLATFORM FOR CIRCULAR RNA DETECTION

    SBC: Lucerna Inc.            Topic: NCI

    Circular RNAscircRNAsare a novel class of modified RNAs that are an abundant component of the epitranscriptomePutative functions of circRNAsinclude miRNA sequestrationRNA binding protein scaffoldingmRNA trappingand protein translation regulationDeregulation in one or more of these roles has been linked to several types of cancerOne well studied circRNAciRSis believed to act as a miRNAsponge and in ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. TOPIC 389- DEVELOPMENT OF A MACHINE LEARNING MODEL FOR PROSTATE CANCER TREATMENT PLANNING

    SBC: NICOLALDE R&D LLC            Topic: NCI

    This project s goal is to develop and test an application that uses Artificial IntelligenceAIto improve consistency and quality of RT treatment plans for prostate cancerBy understanding expert planner preferences in structure contouring and treatment planningand combining this rationale with data amassed in NRG clinical trialsAI models will be trained to produce contours and treatment plans achiev ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. SBIR PHASE 1: SCALABLE DIGITAL DELIVERY OF EVIDENCE-BASED TRAINING FOR FAMILY TO MAXIMIZE TREATMENT ADMISSION RATES OF OPIOID USE DISORDER IN LOVED ONES.

    SBC: We The Village, Inc.            Topic: NIDA

    The project goal is to develop digital delivery of Community Reinforcement and Family TrainingCRAFTmethodologyan empirical family behavioral intervention to improve outcomes around treatment entryfamily functioning and substance use

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Cardiac Monitor for VA ECMO Pediatric and Neonatal Patients

    SBC: TRANSONIC SYSTEMS, INC.            Topic: NHLBI

    PROJECT SUMMARY ABSTRACT Venoarterial Extracorporeal Membrane OxygenationVA ECMOis a way to provide cardiac and pulmonary support to patients without other alternativesThis form of life support is vital to pediatric and neonatal patientsAs with any life supportthere are serious complications that occurThese complications including bleedingthrombosisand infection become more frequent the longer a p ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Towards in vivo high-definition 3D corneal imaging

    SBC: LighTopTech Corp.            Topic: NEI

    The corneathe outermost window of our visual systemis vulnerable to various types of infections and diseasesCorneal disease is one of the leading causes of visual deficiency and blindness !There are nearlymillion bilaterally corneal blind persons worldwideand an estimatedmillion people affected by unilateral corneal blindness globallyIn a conservative estimatecorneal diseases affect nearlypeople i ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. An antigen-capture assay to screen donated blood for Babesia microti

    SBC: Biopeptides, Corp            Topic: NIAID

    PROJECT SUMMARY In the U Smillion individuals receive blood transfusions annuallyIncreasinglythese recipients are being put at risk of infection with Babesia microtia tick transmitted blood borne parasite that resides in red blood cellsRBCsand causes the disease babesiosisBmicroti represents a significant threat to the US blood supply as it survives blood banking procedures and storage conditionsa ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. New high-throughput screening technologies to improve cannabinoid production in yeast.

    SBC: Lucerna Inc.            Topic: NCCIH

    SUMMARY Natural products derived from plants have played crucial roles in the treatments of many diseases throughout historyHoweverscarce natural sources and complex chemical synthesis have limited research and development and increased costs on these productsAn example of this is the non psychoactive cannabinoids found in cannabis plantsThere are overlow abundant cannabinoids that are known to be ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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