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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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ISO 18013-5 Compliant Smartphone-Based Digital Software Badges
SBC: SYNTHETIK APPLIED TECHNOLOGIES LLC Topic: DHS231003The Synthetik team is pleased to provide this Phase I SBIR proposal to develop a distributed, interoperable, ISO 18013-5-compliant and mdoc-based digital software badge (DSB). The DSB will provide the capability to prove a first responder personnel’s identity and qualifications onsite securely and efficiently in a disaster response operating environment.During Phase I we will demonstrate th ...
SBIR Phase I 2023 Department of Homeland Security -
Simulation-based Transfer-learning for Explosive Alarm Resolution Sensors (STARS)
SBC: ASSURED INFORMATION SECURITY, INC. Topic: DHS231004Security at transportation checkpoints is a key strategic aspect of the DHS mission of preventing future attacks against the U.S. and its allies. The ability to freely move assets within, into, and out of the nation is paramount to national security. While DHS currently employs highly-effective explosive alarm resolution sensors (AR), these sensors require special training to operate and produce a ...
SBIR Phase I 2023 Department of Homeland Security -
Clinical biomarker for early prediction of chemotherapy-induced peripheral neuropathy
SBC: NEWVENTUREIQ LLC Topic: 102Project Summary / Abstract Chemotherapy induced peripheral neuropathy (CIPN) is a major side effect of oxaliplatin, a key drug in 1st line regimens for treating colorectal cancer. Dose-limiting CIPN prevents rt25% of patients from receiving full, maximally effective dose of oxaliplatin. In addition, 10-40% of patients receiving oxaliplatin-based therapy for colorectal cancer with develop chronic C ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
A human monoclonal antibody therapy for treatment of hantavirus cardiopulmonary syndrome
SBC: CELDARA MEDICAL, LLC Topic: NIAIDPROJECT SUMMARY Rodent-borne viral outbreaks are increasing in both frequency and impact. As weather patterns evolve, rodent populations are affected and may multiply in areas where increased contact with humans results in infection. Hantaviruses, including Andes (ANDV) and Sin Nombre (SNV), are transmitted through the excreta of infected rodents and, when aerosolized, infect humans. In the Americ ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
VoiceLove: An App-Based COMmunication Tool Designed to Address DeliriUm and Improve Family ENgagement and PatIent/Family SatisfaCtion in CriticAlly Ill PaTiEnts (COMMUNICATE)
SBC: VOICELOVE LLC Topic: N/AICU delirium is a devastating complication of illness, acute trauma, and surgery often resulting in prolonged mechanical ventilation, longer lengths of stay, and long-term disability. Delirium is associated with over 12 times increased odds of developing Alzheimer’s disease (AD) and AD-related dementias (ADRD). In addition, delirium accelerates cognitive decline in AD/ADRD patients. Likewise, pa ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Aerosolized Chemically Modified Tetracycline Nanoformulation for the Treatment of Acute Respiratory Distress Syndrome
SBC: CMTX BIOTECH, INC. Topic: NHLBIPROJECT SUMMARY/ABSTRACT CMTx Biotech is a drug development company working to rescue, develop and commercialize a proprietary clinical-stage drug candidate, incyclinide (CMT-3 / COL-3), for the treatment of sepsis patients at risk of acute respiratory distress syndrome (ARDS). According to the U.S. Centers for Disease Control (CDC), at least 1.7 million American adults develop sepsis annually, re ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Iomab-ACT: A phase I/II study of 131-I apamistamab targeted lymphodepletion followed by CD19-targeted CAR T-cell therapy for patients with relapsed or refractory B-ALL or DLBCL
SBC: Actinium Pharmaceuticals, Inc. Topic: 102ABSTRACT Despite treatment advances, the prognosis of adult patients with relapsed or refractory (R/R) B-cell acute lymphoblastic leukemia (B-ALL) and R/R diffuse large B-cell lymphoma (DLBCL) remains poor. Autologous T- cells modified to express a CD19-targeted chimeric antigen receptor (CAR T-cells) produce durable responses in subgroups of these patients, which has led to FDA approval of two su ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Designing and validating optimal nonaddictive analgesics using the CANDO paradigm
SBC: MEDITATI INC Topic: NIDAABSTRACT We propose a novel holistic paradigm to help solve the opioid crisis by using proteome scale deep learning approaches to design optimal nonaddictive analgesics. We will design compounds that target specific proteins and pathways the combine the pain relieving effects of long acting drugs such as methadone and buprenorphine while modulating additional interactions to ensure optimal pharma ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
PARCA (a digital tool) to improve Justice and Health
SBC: Q2I, LLC Topic: NIDAPROJECT SUMMARY/ABSTRACT Nearly 4.4 million individuals are on community supervision in the United States, with the majority (about 80%) being supervised under probation.1 Justice involved persons (JIPs) have a 474% increased lifetime experience with heroin, a 303% increased use of OxyContin in the last 12 months, and a 256% increased use in pain medication in the last 12 months, compared to the g ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Controlled-release Microbeads to Replace Growth Factors in Fetal Bovine Serum
SBC: STEM CULTURES LLC Topic: 400Scientific Abstract: The frequent use of fetal bovine serum (FBS) to support cell cultures is challenged by lot-to-lot variability, supply constraints, pathogen contaminants and ethical questions. These issues have increased significance due to the burgeoning use of FBS in cell research and therapy development. FBS has been used for over a century to culture cells, but with the need to define cult ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health