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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Analyzing Human Dimensions of Software Engineering Processes

    SBC: APPLIED VISIONS, INC.            Topic: SB172007

    The Secure Decisions team will conduct research to: 1) determine how human dimensions of software engineering (SE) processes influence software security and quality; and 2) develop mechanisms for measuring these relationships in both open source and closed (private) development environments. The human dimensions of interest are: characteristics and behaviors of developers and development teams; en ...

    SBIR Phase II 2019 Department of DefenseDefense Advanced Research Projects Agency
  2. TOPIC 356: FLOUROGENIC ASSAY PLATFORM FOR CIRCULAR RNA DETECTION

    SBC: Lucerna Inc.            Topic: NCI

    Circular RNAs (circRNAs) are a novel class of non-coding RNAs that are an abundant component of the epitranscriptome. Putative functions of circRNAs, include miRNA sequestration, RNA-binding protein scaffolding, mRNA trapping, and protein translation regulation. Deregulation in one or more of these roles has been linked to several types of cancer, including pancreatic cancer, basal cell carcinoma, ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Topic 374: Topical Delivery of Nanoformulated Bioactive Chemopreventive Agent in Skin Cancer

    SBC: VASCULAR VISION PHARMACEUTICAL CO            Topic: NCI

    We plan to evaluate the chemopreventive management of solar ultraviolet (UV) mediated DNA damage by two different Nanoformulation of epigallicatechin-3-gallate (EGCG). The formulations to be assessed under this study include: a) chitosan based formulation of EGCG (nano-EGCG), and b) EGCG containing chitosan based solid lipid nanoparticles (E-Ch-SLNPs). EGCG is well-tested and popular polyphenol in ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Topic 341: Open Scalable Software Infrastructure for Metabolomics Data

    SBC: Kitware, Inc.            Topic: NCI

    Metabolomics research has great potential, and researchers are rapidly producing new techniques for analyzing the large quantities of measurement data in order to utilize metabolomic data more effectively, including promising techniques for data integration across multiple modalities of data from mass spectrometry (MS) and nuclear magnetic resonance (NMR). However, this confluence of data growth a ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Data Sandboxing for Software Binaries

    SBC: Grammatech, Inc.            Topic: SB173003

    Data-rich applications, such as web servers, web browsers, and document editors, are inherently vulnerable to non-control data attacks, i.e., attacks that exploit memory corruption vulnerabilities to leak or corrupt sensitive data. We propose Dobby, a tool that statically transforms software binaries to integrate run-time checks ensuring illicit data flows caused by memory corruption errors in the ...

    SBIR Phase I 2018 Department of DefenseDefense Advanced Research Projects Agency
  6. Optical Cryocooling for Precision Metrology

    SBC: ThermoDynamic Films LLC            Topic: AF10BT02

    Optical cryocoolers, which are compact and produce no vibrations, are ideal for many electronics and sensor applications. In particular, some advanced metrology systems require cooling to around 124 K, the temperature at which the coefficient of thermal expansion for crystalline silicon goes through a null point. Currently, the dominant solid-state cooling technology is thermoelectric cooling, whi ...

    STTR Phase II 2018 Department of DefenseDefense Advanced Research Projects Agency
  7. Processes for Fabrication of Atomically Precise Strongly Correlated Materials

    SBC: Xallent LLC            Topic: ST17C002

    Developing knowledge-driven nanoelectronics for military applications requires understanding the fundamental physics that governs the behavior of the underlying materials. Strongly correlated materials have very desirable properties such as interfacial superconductivity, ferroelectricity, ferromagnetism, and huge magnetoresistance, which make them an ideal set of candidates to integrate with semic ...

    STTR Phase I 2018 Department of DefenseDefense Advanced Research Projects Agency
  8. Mitigation of Supersonic Aircraft Pod Aero-Optics

    SBC: MZA Associates Corporation            Topic: AF103001

    A technical plan is proposed for developing a supersonic pod-based application of virtual duct passive flow control for aero-optic mitigation. Virtual ducts have proven to be a highly effective tool for achieving aero-optic mitigation transonic flight up to Mach 0.8, and the proposed work seeks to leverage our extensive experience in designing and testing transonic virtual ducts to develop a unifi ...

    SBIR Phase II 2018 Department of DefenseDefense Advanced Research Projects Agency
  9. New Platform Technologies for Viral and Therapeutic Evolution Assays

    SBC: Autonomous Therapeutics, Inc.            Topic: SB171003

    From HIV to metastatic cancer, state-of-the-art therapeutics are static biological or pharmaceutical compoundswhose efficacy is inevitably lost once their evolving disease targets sufficiently mutate.We engineered the first adaptive therapeutics designed to co-adapt with adapting disease agentsto provide resistance-proof disease control. Known as Therapeutic Interfering Particles (TIPs), these the ...

    SBIR Phase II 2018 Department of DefenseDefense Advanced Research Projects Agency
  10. Fast Synthetic Scene Generation for Directed Energy Applications

    SBC: TAU TECHNOLOGIES LLC            Topic: AF071010

    Large populations of interacting agents or swarms, are common throughout nature and society and, increasingly, in mechanical and electronic domains. Although the individual agents in such systems are governed by local rules, their collective behavior is often well-orchestrated to solve complex tasks, whether fighting disease, navigating through space to find resources, or to manage social interact ...

    SBIR Phase II 2018 Department of DefenseDefense Advanced Research Projects Agency

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