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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. rAAV5-hCNGB3 Gene Therapy for Achromatopsia: Safety and Efficacy in a Dog Model

    SBC: APPLIED GENETIC TECHNOLOGIES CORPORATION            Topic: N

    DESCRIPTION provided by applicant Complete achromatopsia is an autosomal recessive inherited congenital disorder of retinal cone photoreceptors Patients with complete achromatopsia experience extreme light sensitivity and daytime blindness and best visual acuity under non bright light conditions is usually or worse and generally stable over time In addition to poor acuity hypersensit ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. A Rapid Portable HIV Detection and Monitoring System for Low Resource Settings

    SBC: THERMAL GRADIENT, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Rapid Portable HIV Detection and Monitoring System The long term objectives of this project are Develop a prototype of a rapid portable instrument for detecting and measuring the amount of Human Immunodeficiency Viruses HIVandapos s in samples of patient blood particularly in low resource settings Carry out a pilot study to establish the effectivene ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Long-Acting G-CSF Analog for Treating ARS

    SBC: Bolder Biotechnology, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Development of radiological nuclear medical countermeasures to treat Acute Radiation Syndrome ARS is a high priority research area for NIAID Bone marrow is one of the most sensitive tissues to radiation damage and impaired hematopoiesis is one of the first clinical signs of excessive radiation exposure often resulting i death Granulocyte colony stimulating ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Approach-specific, multi-GPU, multi-tool, high-realism neurosurgery simulation

    SBC: Kitware, Inc.            Topic: 100

    DESCRIPTION provided by applicant Approach specific Multi GPU Multi tool High realism Neurosurgery Simulation Surgical treatment of neurological diseases is complicated and requires advanced training However compressed internship schedules in hospitals creates a challenge to young surgeons to master techniques needed for such complex procedures Surgical simulators are powerful tools to p ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  5. A research and drug development tool for the real time in vitro study of single c

    SBC: KYTARO, INC.            Topic: 100

    DESCRIPTION In this SBIR Phase II PicoCal will develop a high throughput apparatus to measure changes in cell adhesion at the level of individual receptor ligand interactions in real time This tool finds critical applications in research and drug development and would allow researchers to study and manipulate adhesion by bioactive compounds to promote or inhibit physiological processes There is a ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  6. A Multi-channel Web Platform to Provide Holistic Care to Underserved Consumers

    SBC: Transcendent International, LLC            Topic: NIMHD

    DESCRIPTION provided by applicant Significant obstacles exist in care delivery that prevents meaningful utilization of mental health services by consumers who experience health disparities Specifically individuals facing isolation due to linguistic literacy or cultural bariers often face challenges in procuring mental health care These challenges are in part due to the medical and mental systemsan ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Computational tools to analyze SNP data from patients with mental illness

    SBC: PARTEK, INC.            Topic: 101

    DESCRIPTION provided by applicant The broad long term objective of the proposed research is to develop and market a commercial software product that can be used to facilitate the analysis of genetic changes in order to elucidate chromosomal abnormalities that underlie diseases such as autism spectrum disorder bipolar disorder and schizophrenia Recent technological advances allow samples of ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  8. PETE Portable EEG Tool for Education

    SBC: Design Interactive, Inc            Topic: SB131002

    Current EEG technology is restricted to traditional research or clinical venues due to the technical expertise required for use and interpretation of data and the high cost of available systems. Previous attempts at developing low cost systems have resulted in unreliable data output. There is a need to develop portable, easy to use and inexpensive EEG technology that would stream neural data dir ...

    SBIR Phase I 2013 Department of DefenseDefense Advanced Research Projects Agency
  9. Modeling and Optimizing Turbines for Unsteady Flow

    SBC: Florida Turbine Technologies Inc.            Topic: ST13A005

    Pressure gain combustion has the potential to significantly improve the specific fuel consumption for gas turbine engines by realizing a pressure rise through the combustor as opposed to a pressure drop. One drawback to this form of combustion is the cycl

    STTR Phase I 2013 Department of DefenseDefense Advanced Research Projects Agency
  10. Advanced Materials and Methods for Biospecimen Collection for Infectious Disease

    SBC: Viridis Solutions            Topic: ST12B001

    In this Phase I research effort we propose to construct an advanced design for a collection swab to be used for collection and storage of biospecimens. Viridis Solutions and Dr. Magnus Bergkvist and Dr. Melendez (College of Nanoscale Science & Engineering, University at Albany) propose a novel nanofabricated swab that is capable of absorbing and stabilizing biospecimens for long-term storage and ...

    STTR Phase I 2013 Department of DefenseDefense Advanced Research Projects Agency

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