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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Preclinical Development of Semisynthetic Saponin Immunological Adjuvant Titerquil-1055 in the Context of an Influenza Vaccine
SBC: ADJUVANCE TECHNOLOGIES INC. Topic: NIAIDIncreasingly defined vaccines against infectious diseases are better tolerated but less immunogenicrequiring use of an immunological adjuvant for best effectAdjuvance s semi synthetic saponin adjuvant TiterQuilTQLhas shown remarkable efficacy with a variety of antigens with no detectable reactogenicityWhen combined withof the leading vaccines against influenzaFluzoneFluarix and Flublokstriking aug ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
A Liposomal Platform for Spontageous, Particleized Presentation of HIV Trimer Immunogens
SBC: POP Biotechnologies Inc. Topic: NIAIDOver one million Americans andmillion people worldwide are infected with HIVmaking it one of the most pressing public health concerns of our timeUnfortunatelythere are no vaccines available and treatment requires lifelong anti retroviral therapiesThis proposal combines two technologies for the development of a vaccine against HIVEnva novel adjuvantspontaneous nanoliposome antigen particleizationSN ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
TOPIC 356: FLUOROGENIC ASSAY PLATFORM FOR CIRCULAR RNA DETECTION
SBC: LUCERNA INC Topic: NCICircular RNAscircRNAsare a novel class of modified RNAs that are an abundant component of the epitranscriptomePutative functions of circRNAsinclude miRNA sequestrationRNA binding protein scaffoldingmRNA trappingand protein translation regulationDeregulation in one or more of these roles has been linked to several types of cancerOne well studied circRNAciRSis believed to act as a miRNAsponge and in ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
TOPIC #366- PHASE II SBIR CONTRACT- CLONOGENIC HIGH- THROUGHPUT ASSAY FOR SCREENING RADIATION MODULATION
SBC: SUVICA INC Topic: NCIClonogenic assays measure the ability of single cells to proliferate and form a colonyThis process approximates closely the regrowth and recurrence of tumors after treatment with radiation or chemotherapyproviding an assay to screen for drugs that block this processYetclonogenic assays are labor intensive and too cumbersome for high throughout screeningHTSof compound librariesHere we propose to de ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
TOPIC 389- INTELLIGENT SOFTWARE FOR RADIATION THERAPY PLANNING
SBC: RADIASOFT LLC Topic: NCIBesides surgeryradiotherapy is the most effective treatment modality for localized prostate cancerThe success of radiotherapy stems from the exploit of a therapeutic window in tumor response and normal tissue tolerance which maximizes the chance of sterilizing the tumor while sparing the surrounding normal tissue from severe damageThis requires an accurate and individualized radiation dose distrib ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
SBIR PHASE 1: SCALABLE DIGITAL DELIVERY OF EVIDENCE-BASED TRAINING FOR FAMILY TO MAXIMIZE TREATMENT ADMISSION RATES OF OPIOID USE DISORDER IN LOVED ONES.
SBC: WE THE VILLAGE, INC. Topic: NIDAThe project goal is to develop digital delivery of Community Reinforcement and Family TrainingCRAFTmethodologyan empirical family behavioral intervention to improve outcomes around treatment entryfamily functioning and substance use
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Cardiac Monitor for VA ECMO Pediatric and Neonatal Patients
SBC: TRANSONIC SYSTEMS, INC. Topic: NHLBI7. PROJECT SUMMARY/ABSTRACT Venoarterial Extracorporeal Membrane Oxygenation (VA ECMO) is a way to provide cardiac and pulmonary support to patients without other alternatives. This form of life support is vital to pediatric and neonatal patients. As with any life support, there are serious complications that occur. These complications including bleeding, thrombosis, and infection become more freq ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Screening Device for Autism Spectrum Disorders using High Stimulation Rate ABR with Continuous Loop Averaging Deconvolution
SBC: INTELLIGENT HEARING SYSTEMS CORP Topic: NIDCDThe purpose of this proposal is to develop an automated Auditory Brainstem ResponseABRbased neurological screening device and software module that will enhance the early detection of autism and other neurological conditionsAutism Spectrum DisordersASDhave an incidence rate ofBased onmillion births in the United States innew cases of ASD will be diagnosed from that birth cohort aloneThe practice of ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Towards in vivo high-definition 3D corneal imaging
SBC: LighTopTech Corp. Topic: NEIThe corneathe outermost window of our visual systemis vulnerable to various types of infections and diseasesCorneal disease is one of the leading causes of visual deficiency and blindness !There are nearlymillion bilaterally corneal blind persons worldwideand an estimatedmillion people affected by unilateral corneal blindness globallyIn a conservative estimatecorneal diseases affect nearlypeople i ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Bioinformatic Tools for Interpretation of Glycan Array Data
SBC: Z BIOTECH, LLC Topic: 400Project SummaryAbstract There is an urgent need of bioinformatic tools for mining glycan array data in order to accurately and statistically study the interactions between cell surface glycans and glycan binding proteinsWe propose here to develop a software and hardware integrated system for the interpretation of glycan array dataThe problem with existing glycan array data mining tools is that the ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health