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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Plasmodium Falciparum Whole Sporozoite Malaria Vaccine

    SBC: SANARIA INC.            Topic: NIAID

    DESCRIPTION provided by applicant The ideal tool for eliminating Plasmodium falciparum Pf the causative agent of of all malaria deaths would be a highly effective vaccine that prevents blood stage infection and thereby prevents the disease and transmission The only immunogens demonstrated in humans to be able to induce andgt protective efficacy that is sustained months are ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Optimization of a DNA Subunit Regimen for an HIV Vaccine

    SBC: PROFECTUS BIOSCIENCES, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Our primary approach to develop an effective prophylactic vaccine against HIV utilizes a novel immunogen called the Full Length Single Chain FLSC that consists of gp derived from HIV BaL genetically linked via a amino acid linker to the D D domains of human CD Rhesus macaques were inoculated with rhFLSC a surrogate version of FLSC that contains CD derived from rhe ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. A Rapid Portable HIV Detection and Monitoring System for Low Resource Settings

    SBC: THERMAL GRADIENT, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Rapid Portable HIV Detection and Monitoring System The long term objectives of this project are Develop a prototype of a rapid portable instrument for detecting and measuring the amount of Human Immunodeficiency Viruses HIVandapos s in samples of patient blood particularly in low resource settings Carry out a pilot study to establish the effectivene ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Plasmodium Falciparum Whole Sporozoite Malaria Vaccine

    SBC: SANARIA INC.            Topic: NIAID

    DESCRIPTION provided by applicant The ideal tool for eliminating Plasmodium falciparum Pf the causative agent of of all malaria deaths would be a highly effective vaccine that prevents blood stage infection and thereby prevents the disease and transmission The only immunogens demonstrated able to induce andgt sustained months protective efficacy in humans are Pf sporozoit ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Approach-specific, multi-GPU, multi-tool, high-realism neurosurgery simulation

    SBC: Kitware, Inc.            Topic: 100

    DESCRIPTION provided by applicant Approach specific Multi GPU Multi tool High realism Neurosurgery Simulation Surgical treatment of neurological diseases is complicated and requires advanced training However compressed internship schedules in hospitals creates a challenge to young surgeons to master techniques needed for such complex procedures Surgical simulators are powerful tools to p ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Low-Dose MRI-Compatible Molecular Breast Imaging Device

    SBC: Weinberg Medical Physics, Inc.            Topic: 102

    DESCRIPTION provided by applicant Contrast enhanced MRI has been proven to be a very sensitive modality for the early diagnosis of breast cancer in young women and or in women with radiographically dense breasts The American Cancer Society recommends that high risk women with lifetime risk greater than should receive annual breast MRI screening Depending on the practitioner and study char ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Augmented Reality Head Mounted Display for Magnetic Resonance Imaging Guided Inte

    SBC: Robin Medical, Inc.            Topic: 102

    DESCRIPTION provided by applicant The broad long term objective is to develop a low cost easy to use system that can convert diagnostic MRI scanner into a functional neurosurgical MRI suite The specific aims of the project are Develop the display only mode of the HMD that integrates MRI realtime scans and device tracking annotation into a stereoscopic D display Feasibility of such HMD ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  8. DNA Repair-on-a-Chip: Spatially Encoded Microwell Arrays

    SBC: TREVIGEN, INC.            Topic: NIEHS

    DESCRIPTION provided by applicant Preserving genomic integrity is essential in order to suppress cancer neurodegeneration aging and other diseases At odds with genomic preservation is DNA damage which can drive mutations sequence rearrangements and cellular toxicity DNA damage is unavoidable as DNA damaging agents are present in our environment and in our cells To counteract the deleter ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  9. TB Diagnostics at the Point of Care

    SBC: AKONNI BIOSYSTEMS INC.            Topic: NIBIB

    DESCRIPTION provided by applicant Of all diseases tuberculosis TB represents one of if not the greatest health disparity between whites and minorities For every TB infected white person in the United States there are an estimated African Americans Latinos Native Americans Asians and Native Hawaiian Pacific Islanders with this disease Compounded with this dispari ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  10. A Multi-channel Web Platform to Provide Holistic Care to Underserved Consumers

    SBC: Transcendent International, LLC            Topic: NIMHD

    DESCRIPTION provided by applicant Significant obstacles exist in care delivery that prevents meaningful utilization of mental health services by consumers who experience health disparities Specifically individuals facing isolation due to linguistic literacy or cultural bariers often face challenges in procuring mental health care These challenges are in part due to the medical and mental systemsan ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health

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