Award Data

There is a clear gap between commercially available UHF tunable filters and the technology needs of current military communication systems. MEMtronics Corporation, teamed with Purdue University, intend to develop and commercialize technology that fills this gap. The intent of this Phase II project is continue the successful demonstrations began in Phase I and bring the technology to a level of ma ...

Recent studies have shown that embedded systems are extremely vulnerable to security attacks. Some published exploits include remote hijacking of the electronic systems in a modern car and using IP phones and smart televisions to perform covert surveillance of their owners. In this project, we propose a protection system that automatically detects and removes vulnerabilities from embedded software ...

The ability to readily and rapidly detect the concentration of the 9- and 12-amino acid oxytocin analogs will significantly enhance the efficacy of understanding the conditions under which oxytocin is employed by the body. Ionica Sciences will take advantage of recent miniaturization of highly sensitive instrumentation that allows field application of surface enhanced Raman scattering (SERS), a sp ...

With the need to attract and retain students to the science, technology, engineering, and math (STEM) fields, it is important to capture students'interest as early as possible. There are student robotics programs around the nation that appear to provide great excitement for students. These robots require skills in programming and logic, which may be difficult for a first-time programmer. Vide ...

Addressing PTSD and related stress reactions by Service Members and Veterans is one of our country's most important public health challenges. Art therapy has been recognized as a powerful tool enabling"trauma survivors to symbolically express, process and contain feelings they find difficult or impossible to put in to words"(Buk, 2009). Enabling Service Members and Veterans to tell their st ...

Wound management becomes increasingly challenging due to bacterial infections, especially from epidemic drug-resistant strains. To address this problem, Agave BioSystems proposes to develop a RANT (Rapidly Adaptable Nanotherapeutics) breadboard system built upon the modules successfully established in Phase I of this work. The proposed breadboard system will use genomic sequencing data generated ...

DESCRIPTION (provided by applicant): Colorectal cancer is the third leading cause of cancer-related deaths in the U.S. Based on numerous epidemiological studies and recent prospective trials; the use of daily aspirin is associated with a significant reduction in colorectl cancer incidence, deaths and metastatic spread to other organs. However, the chronic use of this drug is limited due to the sid ...

DESCRIPTION (provided by applicant): CD47 has emerged as a novel therapeutic target in hematologic cancers. Leukemias expressing the highest levels of CD47 have the worst prognosis. Increased CD47 expression is thought to protect cancer cells from phagocytic clearance by sending a don't eat me signal to macrophages via SIRPa, an inhibitory receptor that prevents phagocytosis of CD47-bearing ...

DESCRIPTION (provided by applicant): This proposal aims to develop a novel, highly-specific targeted therapy for treatment of breast cancer. The long-term objective is to convert the proprietary intellectual property, the mouse monoclonal antibody (McAb)JAA-F11, which targets the pancarcinoma Thomsen-Friedenreich antigen (TF-Ag) to a humanized form for use as an adjunct with conventional therapy ...

DESCRIPTION (provided by applicant): Mobile phone technology offers a variety of opportunities for innovative approaches to health communication and intervention. These opportunities have been amplified by the emergence of next-generation smartphone devices that are capable of rich multimedia and sophisticated interactivity. Smartphone-based programs can be integrated seamlessly into a user's ...