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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Automatic Detection and Patching of Vulnerabilities in Embedded Systems

    SBC: GRAMMATECH INC            Topic: SB131003

    Recent studies have shown that embedded systems are extremely vulnerable to security attacks. Some published exploits include remote hijacking of the electronic systems in a modern car and using IP phones and smart televisions to perform covert surveillance of their owners. In this project, we propose a protection system that automatically detects and removes vulnerabilities from embedded software ...

    SBIR Phase I 2013 Department of DefenseDefense Advanced Research Projects Agency
  2. Surface Enhanced Raman Scattering-Based Oxytocin Quantitation

    SBC: Ionica Sciences, Inc            Topic: SB132001

    The ability to readily and rapidly detect the concentration of the 9- and 12-amino acid oxytocin analogs will significantly enhance the efficacy of understanding the conditions under which oxytocin is employed by the body. Ionica Sciences will take advantage of recent miniaturization of highly sensitive instrumentation that allows field application of surface enhanced Raman scattering (SERS), a sp ...

    SBIR Phase I 2013 Department of DefenseDefense Advanced Research Projects Agency
  3. Online Graphic Novel/Sequential Art Authoring Tools for Therapeutic Storytelling

    SBC: E-Line Ventures, LLC            Topic: SB112003

    Addressing PTSD and related stress reactions by Service Members and Veterans is one of our country's most important public health challenges. Art therapy has been recognized as a powerful tool enabling"trauma survivors to symbolically express, process and contain feelings they find difficult or impossible to put in to words"(Buk, 2009). Enabling Service Members and Veterans to tell their st ...

    SBIR Phase II 2013 Department of DefenseDefense Advanced Research Projects Agency
  4. PNA-Based Rapidly Adaptable Anti-Microbial Nanoparticles

    SBC: AGAVE BIOSYSTEMS INC.            Topic: SB121003

    Wound management becomes increasingly challenging due to bacterial infections, especially from epidemic drug-resistant strains. To address this problem, Agave BioSystems proposes to develop a RANT (Rapidly Adaptable Nanotherapeutics) breadboard system built upon the modules successfully established in Phase I of this work. The proposed breadboard system will use genomic sequencing data generated ...

    SBIR Phase II 2013 Department of DefenseDefense Advanced Research Projects Agency
  5. Immunoassay for diagnosis of invasive fungal disease

    SBC: Immuno-mycologics, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Early diagnosis of infectious disease is critical to patient outcome. An important early question is - is it a fungus, a bacterium or a virus? A rapid answer to this question would allow preemptive treatment that cansave lives. The goal of this project is a rapid and inexpensive immunoassay that will use serum as a sample to broadly identify the presence of ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Tumor-toxic CD47 mAb therapy for leukemia: a proof of concept study

    SBC: VASCULOX, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): CD47 has emerged as a novel therapeutic target in hematologic cancers. Leukemias expressing the highest levels of CD47 have the worst prognosis. Increased CD47 expression is thought to protect cancer cells from phagocytic clearance by sending a don't eat me signal to macrophages via SIRPa, an inhibitory receptor that prevents phagocytosis of CD47-bearing ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Clinical Translation of an Anti-Metastatic Antibody for Breast Cancer Therapy

    SBC: FOR-ROBIN, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): This proposal aims to develop a novel, highly-specific targeted therapy for treatment of breast cancer. The long-term objective is to convert the proprietary intellectual property, the mouse monoclonal antibody (McAb)JAA-F11, which targets the pancarcinoma Thomsen-Friedenreich antigen (TF-Ag) to a humanized form for use as an adjunct with conventional therapy ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  8. Screens for Novel Agonists/Antagonists of Endocrine Fibroblast Growth Factors

    SBC: AGAVE BIOSYSTEMS INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Agave BioSystems and Professor Makoto Kuro-o at the University of Texas Southwestern Medical Center are proposing a collaborative effort to screen for novel small molecules acting as agonists or antagonists of the Klotho and Klotho- dependent endocrine Fibroblast Growth Factors. The expected outcome of this Phase I effort will be the validation of a high-throug ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Preclinical Efficacy And Safety Evaluation Of Graphene Nanoparticle-based Magneti

    SBC: Theragnostic Technologies Inc.            Topic: NIDDK

    Abstract This STTR phase 1 proposal investigates the safety and efficacy of a novel high-performance carbon nanostructure-based magnetic resonance imaging (MRI) contrast agent for the imaging and monitoring of patients with renal failure. Every year, in the US, approximately 20 million people are treated for mild to severe renal failure. A significant number of cases (greater than 50%) related to ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  10. Image-Based Quantification and Analysis of Longitudinal Lung Nodule Deformations

    SBC: KITWARE INC            Topic: NIBIB

    DESCRIPTION (provided by applicant): Image-based evaluation of pathologies over time is complicated by variability in image acquisition and patient positioning, deformations due to respiratory and cardiac motion, and the clinical standard in radiology of comparing unaligned images. This application proposes a computational method for longitudinal image analysis that captures, illustrates and quant ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
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