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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of NET-Selective Piperidine-Based PET Ligand

    SBC: Acenta Discovery, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): World-wide public health surveys point to an increasing global health burden resulting from serious brain disorders, particularly mood-related disorders such as depression. The economic burden of depression alone is immense. Of the $83.1 billion spent in 2000 on the treatment of depression and related expenses, $26.1 billion (31 percent) were direct medical cos ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Integration, Processing, Retrieval and Organizing

    SBC: Araha, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): This project will develop a new software program that will improve the management of digital information from a variety of sources for individuals with learning disabilities (LD) and/or attention deficit hyperactivity disorder (ADHD) in a postsecondary academic settings. The software to be developed in this project is designed to assist individuals in locating, ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Portable Field Anesthesia Machine

    SBC: Core Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The need for a reliable and safe field anesthesia machine that is portable, lightweight, tippable, does not require compressed gas, easy to setup and maintain, insensitive to shock, and cost effective, has been expressed repeatedly by physicians devoted to civilian and military healthcare in the field. This is amplified by the growing trend towards ambulato ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Functional Genomic Approach to Macrofilaricide Discovery

    SBC: Divergence, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): River blindness and lymphatic filariasis, two disease caused by filarial nematodes, are among the most important tropical diseases. Blackfly transmission of the nematode Onchocercus volvulus leads to river blindness (onchocerciasis), while mosquito-transmitted filarial worms including Wucheria bancrofti and Brugia malayi are responsible for lymphatic filari ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  5. Blood Inhibition Resistant Mutants of Taq DNA Polymerase

    SBC: DNA POLYMERASE TECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The success and sensitivity of DNA detection is limited in important clinical, forensic, and environmental applications due to the presence of complex biological samples, such as blood, which reduce amplification efficiency. Different pre-PCR treatments that are being used to overcome this inhibitory effect in crude specimens significantly increase the duration ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  6. Seizure Prediction System--Clinical Tool for Epilepsy

    SBC: Eegsoft, Inc.            Topic: N/A

    Epilepsy is a neurological disorder, second only to stroke, that affects 1% of the world's population. The overall aim of this project is to develop a commercial epileptic seizure warning and prediction (ESWP) software package for use in electroencephalographic (EEC) monitoring systems from multiple manufacturers. Because of its innovation and the immediate need for such a system in a clinical and ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. A Genome-Derived, Epitope-Driven H. Pylori Vaccine

    SBC: EPIVAX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): EpiVax discovers and develops epitqpe-driven vaccines by screening microbial genomes for protective epitopes. In this application, we describe a genome-based approach for the development of a therapeutic vaccine against Helicobacter pylori disease. First, the H. pylori genome will be scanned for immunodominant Th epitopes by computer-driven (EpiMatrix) analysi ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Novel Smallpox Vaccine Derived from VV/VAR Immunome

    SBC: EPIVAX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): EpiVax specializes in the development of epitope-driven vaccines by screening whole genomes for candidate vaccine components. In this application, we propose to develop a safe, new smallpox vaccine based on epitopes conserved between the vaccinia virus (VV) and Variola (VAR) 'immunomes' that could be used as both a prophylactic and a therapeutic intervention in ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Novel Recombinant Anticoagulant Proteins

    SBC: EVAS THERAPEUTICS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Phase I: Clot formation in the blood vessel (thrombosis) causes a broad range of serious clinical conditions, such as unstable angina, acute myocardial infarction, ischemic stroke, deep vein thrombosis, pulmonary embolism, disseminated intravascular coagulation, and peripheral vascular disease. It is a leading cause of death and disability in the developed coun ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Development of a Mitochondrial Disease Profiling Array

    SBC: GENEPROTECH,INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Mitochondrial disease caused by point mutations in mitochondrial DMA (mtDNA) can be a formidable diagnostic challenge. Because clinical presentation can be variable, multisystemic, and mimic many other neurological disorders, ruling out an mtDNA etiology is difficult in patients with suspected myopathies or encephalopathies. DMA microarrays would seem to prov ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
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