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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Combination Treatment of tPA and Apyrase for Stroke

    SBC: APT THERAPEUTICS, INC.            Topic: NINDS

    DESCRIPTION (provided by applicant): Human apyrase represents a highly promising therapy for acute ischemic stroke which is a leading cause of death and disability with almost no effective therapy for most patients. Using a protein informatics approach, we have successfully engineered a human apyrase which exhibits significantly higher enzymatic activity and platelet inhibition than the wild-type ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  2. Combination Therapy of Aspirin and Apyrase for Stroke

    SBC: APT THERAPEUTICS, INC.            Topic: NINDS

    DESCRIPTION (provided by applicant): Human apyrase represents a highly promising therapy for acute ischemic stroke which is a leading cause of death and disability with almost no effective therapy for most patients. This enzyme strongly inhibits platelet activation and aggregation with modest bleeding risk. We will validate hypothesis that in thromboembolic model of stroke in rats, combination tre ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. TGF-beta Antagonists for Accelerating Wound Healing

    SBC: AUXAGEN, INC.            Topic: NIAMS

    DESCRIPTION (provided by applicant): Every year in the United States, gt1.25 million people suffer from burns, 6.5 million have chronic skin ulcers caused by pressure, venous stasis or diabetes mellitus and 0.25 million have keloids sufficiently severe to require surgery. Burn treatment costs 1.8 billion per year in the US. The treatment of persons with chronic skin ulcers costs 13 billion per y ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  4. Facile Detection of Soil-Transmitted Helminth Infections

    SBC: Divergence, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): The goal of this project is to develop a rapid and accurate immunodiagnostic test for detection of soil- transmitted helminths (STHs) that can be used without laboratory infrastructure. Human STH infections from whipworm (Trichuris), roundworm (Ascaris), and hookworms (Necator and Ancylostoma) create a substantial burden to worldwide public h ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  5. Direct RT-PCR detection of RNA pathogens and mRNA expression in crude samples

    SBC: DNA POLYMERASE TECHNOLOGY, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): We propose to develop a highly simplified and improved method of detecting RNA for use in clinical tests and for scientific research by enabling the RT-PCR amplification of nucleic acids directly in whole blood, serum, plasma, and cell lysates. We propose a dual approach. We will work with two of our blood inhibition Taq mutants combined with a viral reverse tr ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  6. Not Available

    SBC: NANOPARTICLE BIOCHEM, INC.            Topic: NCI

    As part of the SBIR Phase I effort, Nanoparticle Biochem Inc has successfully completed detailed therapeutic efficacy studies of NBI-29 (GA-198AuNP

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a Miniature Plasma Brush for Dental Clinical Applications

    SBC: NANOVA INC.            Topic: NIDCR

    DESCRIPTION (provided by applicant): The main objective of this project is to develop a miniature atmospheric cold plasma brush (m- ACPB) for dental clinical applications. The innovation of this project is the utilization of the recently developed novel non-thermal atmospheric plasma technology for dental treatment to prevent tooth decay and improve the durability and longevity of dental composite ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  8. Process Analytic Technologies (PAT) for Biologics

    SBC: MEDIOMICS, LLC            Topic: NCI

    Biologic drugs are therapeutic medicinal products engineered from living cells or proteins. The novel introduction of these products has already had an enormous impact on some medical subfields, including rheumatology, cardiology, oncology, and others. Biologics are, however, very complicated to manufacture, requiring stringent sanitary conditions for cell-production and growth. Small threats to p ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  9. APTAMER-BASED PINCERS FOR CARDIOVASCULAR BIOMARKERS

    SBC: MEDIOMICS, LLC            Topic: NHLBI

    Not Available

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  10. Establishing Drosophila Tools for Pathway Mapping and Target Identification

    SBC: MEDROS, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): The pharmaceutical industry is under growing scrutiny due to the high failure rate in the clinic and the exorbitant cost of research resulting in expensive medications and growing healthcare expenditures. Increased research and development budgets have had little effect on drugs entering the market place, so clearly a new paradigm for drug discovery is needed t ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
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