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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Passive immunotherapy using plant-derived broadly HIV-1 neutralizing MAbs to prev

    SBC: Plant Vax, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): In the absence of specific intervention and with extended breast-feeding mother-to- child-transmission of HIV reaches a rate of ~35 % and infection of ~700,000 babies worldwide. Passive immunotherapy with a small numberof broadly neutralizing monoclonal antibodies (MAbs) in SHIV challenged macaques bodes well for the ability of infusion of neutralizing MAb to p ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a low-cost hardware accelerator for 3D image registration

    SBC: IGI TECHNOLOGIES, INC            Topic: 102

    DESCRIPTION provided by applicant Our overall goal is to develop a novel computing solution for automatic and accurate registration spatial alignment of dimensional D medical images of any modality and any anatomy rigid or deformable in minute or less Such capability currently does not exist Existing image registration solutions have limited accuracy and or limited applicability p ...

    STTR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  3. Attend BIO conference to meet with potential commercialization partners for ultra-fast MRI technology

    SBC: WEINBERG MEDICAL PHYSICS, INC.            Topic: NINDS

    DESCRIPTION provided by applicant This application represents a competing renewal request for a Phase II STTR project in which we constructed an ultra fast gradient system for magnetic resonance imaging Operation of the novel system is based upon the principle that the nervous system is relatively insensitive to very short exposures to changing magnetic fields As a result we are showing in ...

    STTR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  4. TPM: A Voice-based Tele-PTSD Monitor

    SBC: Intelligent Automation, Inc.            Topic: OSD09H18

    Intelligent Automation proposes to develop voice-based automated Tele-PTSD Monitor (TPM), which can remotely screen, monitor, and provide assistance to clinicians in diagnosing a PTSD patient"s mental healthiness and readiness. A soldier (or other service man/women who may suffer from PTSD) can access the TPM system via a Public Switched Telephone Network (PSTN) or the Internet. The voice data is ...

    SBIR Phase II 2011 Department of DefenseDefense Health Agency
  5. High Performance Signal Processing Tools with Fluctuation-Enhanced Sensing

    SBC: Signal Processing, Inc.            Topic: 9020163R

    We propose a high performance library of signal processing tools that incorporate a newly developed technique known as fluctuation enhanced sensing (FES) to enhance the novel microsensor developed at NIST. Our goal is to improve the performance of the NIST sensor from two angles. One is to apply our existing proven algorithms to the NIST data. The other one is to incorporate advanced FES concept t ...

    SBIR Phase I 2011 Department of CommerceNational Institute of Standards and Technology
  6. Anion Exchange Resins for Chirality-based Separation of Single-wall Carbon Nanotubes

    SBC: Sepax Technologies, Inc.            Topic: 9060663R

    Single chirality of single-walled carbon nanotubes (SWCNTs) is critical for their superb mechanical, thermal, optical and electronic properties. All known methods for producing nanotubes give mixtures of tubes with different chiralities. Physical separation of SWCNT by chirality is thus an enabling step for many potential applications and fundamental studies. The existing anion exchange resins are ...

    SBIR Phase I 2011 Department of CommerceNational Institute of Standards and Technology
  7. Enhanced Security Content Automation Protocol Editor

    SBC: G2, INC.            Topic: 9040577R

    G2 proposes to develop an intuitive, interactive SCAP content creation and editing utility that will provide a user-friendly operating environment. The promise of security automation offers the opportunity for great advances in software assurance, security governance/reporting, and ongoing monitoring activities. Hindering that promise is the fact that current data exchange protocols are cumbersome ...

    SBIR Phase I 2011 Department of CommerceNational Institute of Standards and Technology
  8. Multi-view, Photon Counting DXA Scanner for Quantitative Musculoskeletal Imaging

    SBC: QUANTUM MEDICAL METRICS, LLC            Topic: NIAMS

    DESCRIPTION (provided by applicant): The fragility of osteoporotic bones is largely due to alterations in the underlying structural geometry. Research has demonstrated that it is possible to measure the mechanical geometry of human bones in vivo using dualenergy x-ray absorptiometry (DXA) scans. However DXA scanners are designed to measure bone mineral density (BMD) and not structural geometry. Th ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  9. Targeting host response to DAMP for therapy of Rheumatoid Arthritis

    SBC: Oncoimmune Inc            Topic: NIAMS

    DESCRIPTION (provided by applicant): Rheumatoid arthritis (RA) is among the most common autoimmune diseases. The current treatment for RA is mainly by targeting tumor-necrosis factor (TNF). Despite the remarkable efficacy, significant portion of RA patients are not responsive to this class of drugs. Therefore, there is an urgent need to develop therapeutic that can complement existing therapeutic ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  10. Serum GP88 biomarker as a surrogate marker for disease progression in breast canc

    SBC: A&G PHARMACEUTICAL, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): 40,000 women die annually in the US as a result of breast cancer (BC). Although BC can be controlled if detected early, a significant number is not detected until later and these patients are treated using therapies tocontrol both primary tumor and micro-metastatic disease. Therapy response is monitored using imaging and clinical assessment. Failure to detect e ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
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