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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. An HIV Vaccine Strategy Based on Priming with rVSV Expressing FLSC

    SBC: PROFECTUS BIOSCIENCES, INC.            Topic: R

    DESCRIPTION Based on the prevailing evidence we believe that a highly effective vaccine for HIV prophylaxis must induce long lasting broadly cross reactive antibody responses to envelope that exhibit antiviral activity as well as multi antigen polyfunctional CD and CD T cell responses that produce antiviral chemokines and cytokines and are possibly biased towards an effector memory phenot ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Cryopreservation of Anopheles Embryos

    SBC: SANARIA INC.            Topic: R

    DESCRIPTION provided by applicant The ideal most effective tool for eliminating Plasmodium falciparum Pf the causative agent of of all malaria deaths is a highly effective vaccine that prevents blood stage infection and thereby prevents both disease and transmission Sanariaandapos s goal is to develop and commercialize a Pf sporozoite SPZ vaccine that prevents Pf blood stage infect ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Passive immunotherapy using plant-derived broadly HIV-1 neutralizing MAbs to prev

    SBC: Plant Vax, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): In the absence of specific intervention and with extended breast-feeding mother-to- child-transmission of HIV reaches a rate of ~35 % and infection of ~700,000 babies worldwide. Passive immunotherapy with a small numberof broadly neutralizing monoclonal antibodies (MAbs) in SHIV challenged macaques bodes well for the ability of infusion of neutralizing MAb to p ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  4. Improving Accuracy and Accessibility of Early Autism Screening

    SBC: CHADIS, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): Autism is prevalent (1 in 50 children) and impairing but early intervention has been shown to improve outcomes prompting recommendations for screening at both two year and 18 month health check-ups. Detection of autismearly is crucial but accurate screening tools have been elusive. In Phase II, a practical method of improving accuracy of M-CHAT, the most widely ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Improving Accuracy and Accessibility of Early Autism Screening

    SBC: CHADIS, INC.            Topic: 103

    DESCRIPTION provided by applicant Autism is prevalent in children and impairing but early intervention has been shown to improve outcomes prompting recommendations for screening at both two year and month health check ups Detection of autism early is crucial but accurate screening tools have been elusive In Phase II a practical method of improving accuracy of M CHAT the most widel ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Infant Assessment of Early Communication Risk Factors: The ISCBS (formerly ECBS)

    SBC: PAUL H BROOKES PUBLISHING CO., INC.            Topic: NIDCD

    DESCRIPTION provided by applicant Effective early intervention depends on reliable identification of risk for communication impairments as soon as possible Established infant risk factors for communication impairments include poor turn taking gestures receptive language commenting symbolic play and speech Although these risk factors can be detected by mos and reliably predict late ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Recombinant antigen diagnostics for filoviruses

    SBC: CORGENIX MEDICAL CORPORATION            Topic: NIAID

    DESCRIPTION provided by applicant The proposed project will further develop marketable ELISA and lateral flow immunoassay diagnostics LFI in both monoplexed and multiplexed formats for the NIAID category A BSL filoviruses and will drive pre clinical development and validation for these diagnostics These assays will be used for diagnosis of Ebola virus EBOV Sudan virus SUDV and Marbu ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Development of the first HRV vaccine

    SBC: BIOLOGICAL MIMETICS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Human rhinoviruses HRV are the leading cause of common colds and virus induced exacerbation of asthma and chronic pulmonary diseases In addition HRV can cause severe lower respiratory tract infections in children the elderly and immune compromised patients The economic burden of the common cold is estimated to be about $ B each year in the US in terms o ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. In vivo conjugated multivalent toxoid-polysaccharide vaccine for S. aureus

    SBC: Integrated Biotherapeutics, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Staphylococcus aureus is a Gram positive human pathogen that causes a wide range of infections from skin and soft tissue infections SSTI to life threatening sepsis and pneumonia The pathogenicity of S aureus is dependent on numerous virulence factors including cell surface proteins and polysaccharides as well as secreted toxins An important group of thes ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Rapid STEMI Fibrinolysis for Underserved Populations

    SBC: Pulse Therapeutics, Inc.            Topic: NIMHD

    DESCRIPTION provided by applicant Coronary heart disease CHD accounts for every of deaths in the United States US with acute incidences estimated at M annually Of these up to are classified as ST elevation myocardial infarction STEMI in which a clot blocks a coronary artery leading to a change in the ECG ST wave Because the heart muscle rapidly dies time to re ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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