Award Data

The objective of this project is to develop and validate improved methodology for the substantiation and the usage-based tracking of rotorcraft dynamic system components. A Helicopter Information Retrieval & Substantiation System(HIRSS) is proposed whichconsists of (1) an Universal Damage Tracking Algorithm(TM) capable of accommodating the different fatigue analysis methodologies of the manufactu ...

We propose a breakthrough technique for ultra rapid, sensitive detection of cancer specific chromosome rearrangements in solution to facilitate bulk quantification of tumor cells for early detection of metastatic tumor cells in bone marrow, lymph nodes,and peripheral blood. Combining two separate, novel techniques (1) hybridization of chromosomes in suspension using (2) Repeat Sequence Depleted D ...

Multichannel Scaler (MCS) electronics are currently used in lidar-based remote sensing applications for photon counting and histogramming functions. As front-end photon detector technology improves, the need for advanced, high-performance multichannel scalers will increase so as to not limit system performance. This proposal describes a high-speed, low power MCS chip design and circuit board that ...

This proposal addresses the design and development of dynamically controlled protein crystal growth payloads for Space Station application. The Space Station will afford the protein crystal growth community the unprecedented opportunity to grow crystals in a microgravity environment for extended periods of time and then retrieve them. This will add a new dimension to determining the structures of ...

This proposal addresses the design and development of dynamically controlled protein crystal growth payloads for Space Station application. The Space Station will afford the protein crystal growth community the unprecedented opportunity to grow crystals in a microgravity environment for extended periods of time and then retrieve them. This will add a new dimension to determining the structures of ...

Brimrose proposes to develop miniaturized acousto-optic tunable filter (AOTF)based multi-spectral imaging radiometer. This radiometer will operate in the wavelength range of 1 to 2.5um. We propose a novel fabrication procedure to make it capable of withstanding extreme environments of space. It involves moving parts, has high throughput and extremely fast scanning capability. The work focuses on 4 ...

A high precision laser range finder is proposed for applications in spaceborne telescopes and interferometers. A new kind of spatially adaptive optical frequency sensor is integrated with the Coherent Frequency Domain Reflectometry, leading to high precision laser range finder with broad measurement dynamic range and large baselines. Adjustable spatial resolution ranging from several centimeters d ...

A high precision, adaptive, and low-cost laser velocimeter is proposed for aerodynamic applications. We adopt a new kind of optical Doppler frequency sensor to detect Doppler frequency shifts caused by air flows. High speed investigation of aerodynamics is enabled by the fast response times of the novel Doppler frequency sensors. It is proposed here to demonstrate to NASA the compact laser velocim ...

Current space water reclamation systems require resupply and expendable use that are too large for long duration remote space applications such as Mars expeditions and lunar bases. We propose development of a novel jet-induced cavitation process for water reclamation that would be lightweight, low maintenance, reliable, and require little or no expendables. Cavitation is known to produce reactions ...

Current serum biomarkers for cancer do not approach the ideal of 95% sensitivity andspecificity. Tumor-associated fatty acid synthase (FAS) has been identified as animmunohistochemical marker potentially useful in monitoring tumor aggressiveness andpredicting disease course. FAS can be detected in sera of individuals with pre-neoplasticdiseases, as levels increase as disease progresses. In a fi ...