Award Data

DESCRIPTION (provided by applicant): In the absence of specific intervention and with extended breast-feeding mother-to- child-transmission of HIV reaches a rate of ~35 % and infection of ~700,000 babies worldwide. Passive immunotherapy with a small numberof broadly neutralizing monoclonal antibodies (MAbs) in SHIV challenged macaques bodes well for the ability of infusion of neutralizing MAb to p ...

DESCRIPTION (provided by applicant): There are an estimated 26 million Americans with early chronic kidney disease (CKD). Early diagnosis and treatment are the only cost-effective means to reverse this growing problem. NIH recognizes the challenge to diagnose CKD early during its initiation and development phases in order to prevent further renal damage, reduce cardiovascular risk, and minimize th ...

DESCRIPTION provided by applicant Excessive alcohol use is associated with a range of serious and costly health social and economic consequences at the individual and societal level This program of research serves as a venue by which to produce and test an innovative science based and cost effective means to intervene in a private convenient and individualized way with employed adults wh ...

DESCRIPTION provided by applicant Our overall goal is to develop a novel computing solution for automatic and accurate registration spatial alignment of dimensional D medical images of any modality and any anatomy rigid or deformable in minute or less Such capability currently does not exist Existing image registration solutions have limited accuracy and or limited applicability p ...

DESCRIPTION provided by applicant This application represents a competing renewal request for a Phase II STTR project in which we constructed an ultra fast gradient system for magnetic resonance imaging Operation of the novel system is based upon the principle that the nervous system is relatively insensitive to very short exposures to changing magnetic fields As a result we are showing in ...

NIST and G2 have been on the forefront of security automation with the development of the Security Content Automation Protocol (SCAP). However, the barrier to entry for SCAP content creation is the requirement to have in depth knowledge of the underlying specifications. This project aims to allow security experts to create SCAP content without the need to be an expert in the specification. By leve ...

Intelligent Automation proposes to develop voice-based automated Tele-PTSD Monitor (TPM), which can remotely screen, monitor, and provide assistance to clinicians in diagnosing a PTSD patient"s mental healthiness and readiness. A soldier (or other service man/women who may suffer from PTSD) can access the TPM system via a Public Switched Telephone Network (PSTN) or the Internet. The voice data is ...

Active Signal Technologies proposes to further develop its self applied, electrodeless home monitoring device for sleep apnea with the ultimate goal of making clinical diagnosis available to a much larger population of sleep disorder patients than currently possible. Preliminary results from Phase I have shown that much of the diagnostically rich airflow information captured in the sleep lab with ...

DESCRIPTION (provided by applicant): This proposal is to develop a method to prolong the shelf-life and increase the safety of human platelets with a unique method of sterilization. The method delivers an agent known to kill a range of microbial pathogens in vitro including many bacterial species known to contaminate platelet concentrates, fungi, parasites, and vir ...

DESCRIPTION (provided by applicant):The goal of this proposal is to establish the value of the 3' noncoding region (NTR) of hepatitis C virus ((HCV genome as an amplification target in a viral load assay. HCV is the most prevalent chronic bloodborne infection in the U.S. Although the number of new infections has declined substantially, there are still an estimated 36, ...