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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. SBIR Phase I: Reactive Cyclic Induction Marine Diesel Emissions Reduction Monitoring and Delivery System Project

    SBC: STec. Technology, Inc.            Topic: ET

    The broader impact of this Small Business Innovation Research (SBIR) Phase I project is the potential reduction of toxic nitrogen oxides (NOx) and harmful carbon dioxide (CO2) emissions from marine diesel engines. There are approximately 4 million diesel-powered craft in use globally, emitting approximately one billion tons of CO2 and 100 million tons of NOx annually. This project seeks to remove ...

    SBIR Phase I 2023 National Science Foundation
  2. High-resolution/high-precision PEM Quality Control

    SBC: RESONON, INC.            Topic: C5618h

    High-quality, defect free, and consistent thickness Proton Exchange Membrane (PEM) films are required to ensure maximum efficiency and longevity over the life of hydrogen fuel cells or electrolyzers utilizing this technology. The current technologies of PEM film Quality Assurance (QA) and defect detection rely on human inspection, which can be subjective and labor intensive, or measurement technol ...

    SBIR Phase I 2023 Department of Energy
  3. Next Generation Microlayer Annular Co-Extrusion

    SBC: Guill Tool & Engineering Co, Inc.            Topic: C5620c

    Annular extruded plastics are in everything from fuel lines, hoses, pipes, and wires to catheters, medical tubing, and stents and makes up about ? of the $200B extruded plastics market. Extrusion manufacturing is a major processor of the $600B raw plastics industry, which produces 380 million metric tons of material each year. The production of these materials accounts for 4% of oil consumption an ...

    SBIR Phase I 2023 Department of Energy
  4. A low-cost snow water equivalent sensor

    SBC: NWB SENSORS INC            Topic: 84

    Project SummaryAccumulated snowpack is a major source of water throughout the United States. Accuratelymonitoring snow on the northern plains is a significant need for streamflow forecasting andreservoir management. This has been demonstrated by the US Army Corp of Engineersestablishment of the Upper Missouri River Basin Plains Snow and Soil Moisture MonitoringNetwork. The availability of a low-co ...

    SBIR Phase I 2023 Department of Agriculture
  5. Tumor Antigen Targeted Nanoparticle Therapy for Glioblastoma (GBM)

    SBC: NANOVALENT PHARMACEUTICALS INC            Topic: 102

    Project Summary The goal of this Fast Track STTR project is to determine proof-of-principle and efficacy of a novel blood brain barrier (BBB) penetrating therapeutic nanoparticle for the potential treatment of otherwise intractable brain tumors like glioblastoma multiforme (GBM). This project seeks to demonstrate that novel, targetable nanoparticles can delivery therapeutic substances to human bra ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Validation and Improvement of ISPRI-HCP: An Innovative Platform for Immunogenicity Risk Assessment of Process-related Protein Impurities

    SBC: EPIVAX, INC.            Topic: NIAID

    ABSTRACT The identification and removal of process-related protein impurities (PRPI) from biologic products is a critical step in drug development. Despite recent improvements in the purification and processing of biologics, the presence of immunogenic PRPI continue to raise concerns about drug safety and efficacy. We propose an innovative approach for assessing immunogenicity risk of PRPI using o ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Previvors Recharge: A Resilience Program for Cancer Previvors

    SBC: Pro-Change Behavior Systems, Inc.            Topic: 102

    It is estimated that approximately 5-10% of all diagnosed cancers are caused by Hereditary Cancer Syndromes (HCS) that are associated with germline mutations (inherited genetic mutations passed directly from a parent to a child that create a genetic predisposition to certain types of cancer). Recent epidemiologic models indicate that 1 in 279 people may be carriers of one of the most common HCS, a ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Beat Extreme: An Interactive, Tailored Text Messaging Program Combining Extreme Weather Alerts with Hyper-localized Resources and Actionable Insights for Addressing Climate Change

    SBC: Pro-Change Behavior Systems, Inc.            Topic: R

    Summary Climate change is an urgent public health threat, and climate-related health risks disproportionately impact vulnerable populations. Public health agencies have underscored the need to develop scalable and innovative health-equity centered, multi-level interventions that offer tools and resources to 1) raise awareness of the inextricable link between climate change and health and 2) suppor ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Plans4Care: Personalized Dementia Care On-Demand

    SBC: Plans4Care INC            Topic: R

    PROJECT ABSTRACT Although rt11 million family/friends are caregivers to rt6 million people with Alzheimer's Disease (AD) and AD- Related Dementias (AD/ADRD), they do not typically receive personalized education, strategies and support to manage their own wellbeing and complex dementia-related symptoms. Lack of personalized care contributes to $321 billion annually in AD/ADRD care costs. In respons ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  10. Inter-alpha Inhibitors in Hypoxic-Ischemic Brain Injury

    SBC: PROTHERA BIOLOGICS, INC.            Topic: 105

    Perinatal brain injury resulting in mental retardation and cerebral palsy is the most severe disability in children and affects 40-148 in preterm and 1–2/1000 in full term infants. This places a huge burden on society, emphasizing the critical need for improved prevention/treatment strategies to decrease perinatal brain injury. Hypothermia (HT) is the only FDA approved therapy to attenuate brain ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
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