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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Development of Equipment Washers for Invasive Plant Protection

    SBC: Kennedy, Sheilah A            Topic: 081FH3

    SK realistic estimated timeline of 18 months maximum, hopefully sooner, will allow for design, engineer and testing modifications to be addressed. SK learned from Phase II that even the simple modifications can result in hours of engineering and design work. The successful completion of the DOTWASH system was designed and developed. The overall components were tested with good operating capabiliti ...

    SBIR Phase II 2014 Department of Transportation
  2. Eco: An Online Virtual World for Secondary School Environmental Literacy and Collaborative Problem Solving

    SBC: STRANGE LOOP GAMES INC.            Topic: N/A

    The project team is developing a prototype of Eco, a multi-player game to prepare high school students to be environmentally literate citizens with 21st century skills. To play the game, students will enter a shared online world featuring a simulated ecosystem of plants and animals. Students will co-create the civilization by measuring, modeling, and analyzing the underlying ecosystem. Students ad ...

    SBIR Phase I 2014 Department of Education
  3. Vasoactive Intestinal Peptide for the treatment of Female Sexual Arousal Disorder

    SBC: PharmaIN Corporation            Topic: NIA

    DESCRIPTION (provided by applicant): Female sexual arousal disorder (FSAD), one of the conditions commonly described as Female sexual dysfunction (FSD) is common among older women and can be a significant reason for decreased quality of life in the aging population. FSAD is defined as the persistent or recurring inability to attain or maintain sufficient sexual excitement, causing personal distres ...

    SBIR Phase I 2014 Department of Health and Human Services
  4. A Self-Contained Assay Device for Rapid Detection of Viable Cryptosporidium in Wa

    SBC: Biodetection Instruments, Inc            Topic: NIAID

    DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase I project will investigate the technical feasibility of an in vitro excystation-based automated cartridge assay for rapid detection of viable Cryptosporidium oocysts in water. Briefly, viable oocysts will be subjected to an in vitro excystation step to release sporozoites and the antigens for detection on a patent-p ...

    SBIR Phase I 2014 Department of Health and Human Services
  5. Non-invasive Diagnostic Platform Development for Celiac Disease Remission Status

    SBC: ADAPTIVE BIOTECHNOLOGIES CORPORATION            Topic: NIAID

    DESCRIPTION (provided by applicant): The purpose of this proposal is to adapt a technology that we have developed for monitoring residual disease in leukemia patients to monitor residual autoimmune disease in Celiac Disease patients. Celiac disease hasa significant burden on quality of life, as it is one of the most frequent autoimmune diseases, with an estimated prevalence of approximately 1% ...

    SBIR Phase I 2014 Department of Health and Human Services
  6. Targeted Enzyme Replacement Therapy for Rare Forms of Osteogenesis Imperfecta

    SBC: Biostratagies, LC            Topic: NIAMS

    DESCRIPTION (provided by applicant): The long-term goal of this project is to develop an effective protein replacement therapeutic (PRT) for patients affected with rare forms of Osteogenesis imperfecta, OI-VIII (deficiency in prolyl 3-hydroxylase 1; P3H1)and OI-VII (deficiency in cartilage associated protein CRTAP). These PRTs will integrate the safety and cost advantages of plant-based bioproduct ...

    SBIR Phase I 2014 Department of Health and Human Services
  7. Immune-based brain cancer diagnostic for rapid, accurate disease classification

    SBC: HealthTell Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): Accurate, early disease diagnosis and monitoring are critical aspects to effective prevention, treatment, and remission of disease. Most diagnostic methods available today are not simple or sensitive enough to significantly impact patients' response to treatment or survival outcome. This unmet need is highlighted by diseases, such as brain cancers, that o ...

    SBIR Phase I 2014 Department of Health and Human Services
  8. Tumor Tight Junction Opener + Chemotherapy Conjugates to Treat Cancer

    SBC: PAI Life Sciences, Inc.            Topic: NCI

    Project Summary Tumors survive cancer therapy in part by blocking the entrance and permeation of drugs into the cancer. We have developed a therapeutic, JO-1 , that selectively opens up tumors, which dramatically enhances penetration. This results in markedly increased concentrations of cancer drugs in the tumor, which becomes a sink , thereby reducing drug levels in the rest of the body. JO-1 m ...

    SBIR Phase I 2014 Department of Health and Human Services
  9. Development of an Ad5-CEA/Brachyury Vector Approach for Cancer Treatment

    SBC: Etubics Corporation            Topic: NCI

    DESCRIPTION (provided by applicant): With the discovery of new biomarkers associated with tumor development, many of these tumor-associated antigens (TAA) are being utilized in immunotherapeutic modalities designed to induce anti-tumor directed cytotoxicimmune responses. It is increasingly clear that not any one of these TAA is sufficient, as a single entity to develop an immunotherapeutic treatm ...

    SBIR Phase I 2014 Department of Health and Human Services
  10. Treatment of non-small cell lung cancer with a CCL14 monoclonal antibody

    SBC: ONCOFACTOR CORPORATION            Topic: NCI

    DESCRIPTION (provided by applicant): Lung cancer is the most prevalent cancer worldwide and responsible for the most cancer deaths in the United States. Existing therapies include surgery, radiation, or chemotherapy to kill the tumor cells, but these options are not adequate for the vast majority of patients. Thus, there is a significant need to develop new therapeutic approaches. One of the most ...

    SBIR Phase I 2014 Department of Health and Human Services
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