Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Pancreatic Ductal Adenocarcinoma Targeted Ultrasound Contrast Agent Development

    SBC: NUVOX PHARMA, L.L.C.            Topic: 102

    Pancreatic ductal adenocarcinomaPDACis a highly lethal form of cancerIn most patientsdetection is at an advanced stage and the outcome is poorThis project is directed towards development of a molecularly targeted ultrasound contrast agent with potential to detect early stage disease while still curableIn Phase I of this projectwe incorporated the engineered human single chain variable fragmentscFv ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Integrating CNV analysis into a NextGen sequencing clinical analytics platform

    SBC: Golden Helix, Inc.            Topic: 400

    Abstract The goal of this project is to develop a commercial analysis software platform that features the ability to detect and interpret copy number variantsCNVsand other types of structural variationsSVsfrom short read NextGen SequenceNGSdata to enable comprehensivewidely accessibleand economical genetic testingThis capability is key in clinical and research applicationsFor examplecurrently clin ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Targeted Polymerized Shell Microbubbles to Image and Treat Surgical Adhesions

    SBC: NanoValent Pharmaceuticals, Inc.            Topic: 300

    Project Summary The long term goal of this Phase II SBIR project is to develop a commercially viable ultrasound contrast reagentUCRthat will allow the noninvasive identification and treatment of newly forming abdominal adhesions after surgerySuccessful implementation would have significant impact because we would both improve patient post surgical monitoring and considerably reduce the cost of adh ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Selective inhibition of CYP26A1 in the skin for the treatment of ichthyosis

    SBC: Dermaxon LLC            Topic: NIAMS

    Project SummaryAbstract DermaXon s project goal is to develop efficacious substrate based and highly selective inhibitors of CYPsthe enzymes responsible or retinoic acidRAmetabolism in the epidermisfor the topical treatment of ichthyosisThis approach will provide a therapeutic advantage in ichthyosis without the potential adverse effects mediated by non targeted Pinhibitionassociated with previous ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. GUANIDINIUM DERIVATIVES FOR THE TREATMENT OF OCULAR PAIN

    SBC: Siteone Therapeutics, Inc.            Topic: N

    PROJECT SUMMARY The absence of safe and effective strategies for the management of ocular pain is motivating the development of a novel topical drug suitable for patient self administrationConventional local anestheticssuch as proparacaineinhibit voltage gated Naion channelsNaVand are highly effective for the management of ocular pain in acutein office settingsHoweverthese agents are short acting ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Lab-To-Marketplace: Commercialization of a stretchable microelectrode array

    SBC: BMSEED LLC            Topic: 101

    Project Summary Abstract The proposed work is directed at the commercialization of BMSEEDandapos s Micro Electrode Array Stretching Stimulating und Recording EquipmentMEASSuREtechnologyMEASSuRE bridges the gap between in vitro and in vivo research by simulating the biomechanical and electrical environment of cells in the body in a controlled environment outside of the bodyThe applications for MEAS ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Deep Learning to Transform Clinician Autism Diagnostic Assessments and More

    SBC: Caring Technologies Inc.            Topic: 103

    NODA Telehealth system improves access to an autism diagnostic assessment by guiding families to share video clips of their child at homeso diagnostic clinicians can directly observe andtagvideo of any atypical behaviorand if warrantedrender a diagnosisThis system is evidence based and has been commercializedwith several published studies to discuss the benefitsWe now propose to improve this servi ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Picosecond Timing Measurement IC for Particle Physics Experiments

    SBC: Alphacore, Inc.            Topic: 27j

    Several high energy physics experiments require accurate timing measurements and transient digitization at high sampling rates, equaling or exceeding 5 gigasamples per second (GSPS). To date, only a few transient digitizer chips have been developed for this purpose and they are based on storing the analog samples onto long buffers from which they are digitized with low-rate analog-to-digital conve ...

    SBIR Phase II 2018 Department of Energy
  9. RADIATION HARD HIGH SPEED CAMERA SYSTEM FOR ACCELERATOR BEAM DIAGNOSTICS

    SBC: Alphacore, Inc.            Topic: 24h

    Alphacore intends to submit a proposal for a Sequential Phase IIA grant in January 2018. Thus far in Phase II Alphacore has developed an initial prototype of a radiation-hardened 10,000-pixel camera with custom- designed 10,000-frames-per-second (10kpfs) capable image sensor IC, camera control PCB with FPGA and interface to a PC, and an enclosure allowing different lens options. Most of Alphacore' ...

    SBIR Phase II 2018 Department of Energy
  10. Sub-Scale Fly Along Sensor Package

    SBC: CONTROL VISION INC            Topic: MDA16017

    During this SBIR program, Control Vision, Inc. will develop an innovative sub-scale Fly Along Sensor Package (sFASP) which will be deployed from a Ballistic Missile Defense System flight test target AO deployment canister.This sFASP will give unprecedented sensor visibility into Ballistic Missile Defense System test scenes providing truth data to the many different areas of Missile Defense.Approve ...

    SBIR Phase II 2018 Department of DefenseMissile Defense Agency
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