Award Data

THE OBJECTIVE OF THIS RESEARCH PROJECT IS TO PRODUCE A PORTABLE, MINIATURIZED DIALYSIS MACHINE WHICH IS SIMPLE, SAFE, AND SYMPTOM-FREE IN OPERATION. THIS DIALYSIS MACHINE SHOULD ALLOW THE AVERAGE HEMO-OR PERITONEAL DIALYSIS PATIENT TO PERFORM DIALYSIS BY HIMSELF AT HOME, UNASSISTED. THE MACHINE WILL BE SMALL (12 LBS.), PORTABLE, AND TOTALLY SELF-CONTAINED (WITHOUT NEED FOR CONNECTION TO WATER SUPP ...

MEDICAL SCIENCE HAS PROGRESSED TO THE POINT THAT CATHETERS AND ANGIOSCOPES CAN BE USED FOR DIRECT VISUALIZATION OF THE INTERIOR SURFACES OF THE HEART AND CORONARIES. THE PRIMARY HINDRANCE TO FURTHER PROGRESS IN THIS FIELD IS THE LACK OF A MINIATURIZED ANGULATION SYSTEM. THE PROPOSED CONCEPT SUGGESTS THAT PROPRIETARY MATERIALS BE INCORPORATED INTO THE TIP OF A CATHETER OR ANGIOSCOPE TO MAKE THEM MA ...

RETROVENOUS DIASTOLIC MYOCARDIAL PERFUSION (RVDP) WITH OXYGENATED BLOOD VIA THE CORONARY SINUS AND CORONARY VEINS HAS BEEN SHOWN EXPERIMENTALLY TO PROVIDE 45% OF THE NORMAL CORONARY BLOOD FLOW. RVDP THERAPY COULD SIGNIFICANTLY ALTER THE MORBIDITY OF PATIENTS WITH CORONARY ARTERY DISEASE AND ACUTE MYOCARDIAL ISCHEMIA. CURRENT EXPERIMENTAL RVDP CATHETERS REQUIRE A SECOND ARTERIAL SOURCE OF OXYGENATE ...

MULTIMONITORS FOR ECG, TEMPERATURE, HEART SOUNDS, AND BREATH SOUNDS WILL BE FABRICATED ON ENDOTRACHEAL TUBES AND BENCH TESTED. THE CAPABILITY OF MONITORING MULTIPLE PHYSIOLOGIC PARAMETERS FROM A SINGLE ANATOMIC SITE (THE TRACHEA) IS COST EFFICIENT IN TERMS OF CURRENT PRACTICE AND WILL PROVIDE BETTER PATIENT CARE. THE MULTIMONITOR ENDOTRACHEAL TUBES WILL BE TESTED IN SHEEP AND DOGS AND THE PHYSIOLO ...

THE PROPOSED RESEARCH WILL SATISFY THE INCREASINGLY PRESSING NEED FOR DIETARY MINERAL ASSESSMENTS, ESPECIALLY AS RELATED TO CANCER EPIDEMIOLOGY, BY ESTABLISHING A NEW ANALYTICAL METHOD FOR LOW-COST, NONDESTRUCTIVE MULTIELEMENT ANALYSIS OF SOLID AND LIQUID FOODS. SPECIFIC AIMS AND EXPECTED RESULTS OF THE PROPOSED FEASIBILITY RESEARCH ARE: VALIDATION OF THE NEW METHOD FOR X-RAY FLUORESCENCE (XRF) AN ...

WE PROPOSE TO DEVELOP THE APPLICATION OF NEW TWO DIMENSIONAL, STATE OF THE ART CHARGE COUPLED DEVICE (CCD) IMAGE DETECTORS TO THE PROBLEM OF ANALYSIS OF PROTEINS BY DIGITIZATION OF TWO DIMENSIONAL POLYACRYLAMIDE ELECTROPHORETIC GELS. LONG TERM SUCCESS OF THIS PROJECT WILL RESULT IN COMMERCIALIZATION OF A NEW PRODUCT LINE OF MEDICAL MACHINERY, MORE WIDESPREAD USE OF ELECTROPHORESIS IN A CLINICAL SE ...