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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Intracranial Brain Function Mapping System

    SBC: CHATTEN ASSOC., INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We will develop a modern, computer-controlled electrical stimulator for performing functional mapping by cortical stimulation. The primary application is for use with patients who are candidates for surgery to control or eliminate occurrence of epileptic seizures. Other applications will include functional mapping to plan surgery for other brain diseases such a ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  2. POPULATION SCALE HLA TYPING FOR HOMELAND DEFENSE

    SBC: GENOMICS USA, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Current technology for HLA typing does not have rapid field response capability because it too expensive and is too complicated to be implemented in the context of a population-scale emergency. The ultimate goal of this proposal is to develop a simple, accurate, low cost method to perform complex HLA typing through development of an "HLA Chip" which will enable ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Optimization, Expansion & Validation of Alzheimers Lymphocyte Proliferation Test

    SBC: GW MEDICAL TECHNOLOGIES, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): In GW Medical Technologies' Phase I effort, the company demonstrated the LymProTM (lymphocyte proliferation) Test's feasibility as a blood test for Alzheimer's disease. However, much work still needs to be done to fully prove the LymPro's capabilities and define its limitation before the Test can be useful in a clinical environment. In this proposed effort, GW ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  4. Mass Spectrometry Assays for Biodefense

    SBC: INTRINSIC BIOPROBES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this Phase II Research Proposal is to continue the successfully completed work of the Phase I Research project by further developing affinity-based mass spectrometry assays for the detection/characterization of Biodefense agents, specifically the family of Staphylococcal Enterotoxins (SE). The assays will utilize affinity capture in pipette-fit ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Movement Analysis to Monitor Medication Side Effects

    SBC: NEUROSCRIPT, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Clinical trials of new medications often rely on subjective, observer-based ratings of side effects in the form of movement abnormalities to evaluate safety and tolerance of medication dosage. Imprecise ratings of adverse side effects have led to inconsistent results from these trials. Well-known adverse effects are extrapyramidal motor side effects (EPS), whic ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  6. In vivo Thermoacoustic Imaging of HER2 Status

    SBC: OPTOSONICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): In this Fast Track application, we propose developing the novel imaging technology and molecular probe that will enable the non-invasive detection and quantification of HER2 overexpression in breast cancers. The approach we are promoting is to label Herceptin, a therapeutic mono-clonal antibody, with an infraredabsorbing dye, and then to detect the presence ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  7. PI-3 kinase inhibitor PX-866 as anticancer therapy

    SBC: PROLX PHARMACEUTICALS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): One in every four deaths in the US is due to cancer. The overall cancer drug market exceeds $2 billion in the USA. There is significant need to identify novel and selective small molecule-based cancer therapies. This proposal seeks to undertake late preclinical development of a novel inhibitor of phosphatidyl inositol 3-kinase for the eventual use of the agent, ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Functional Health CAT in Chronic Kidney Disease

    SBC: QUALITYMETRIC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to apply item response theory (IRT) and computerized adaptive testing (CAT) to achieve major advances in the standardization of Chronic Kidney Disease (CKD) health-related quality of life (HRQOL) metrics, in the efficiency of data collection and processing technologies, and in the usefulness of clinician and patient reports. In contrast to static ins ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  9. Computerized Adaptive Assessment of Headache Impact

    SBC: QUALITYMETRIC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose a tool for evaluating the functional impact of headaches that uses computerized adaptive testing (CAT) to achieve more practical and more precise assessments by matching the questions to each patient's headache severity level. In previous work, we developed a headache impact item bank that improved score precision and validity and provided measuremen ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  10. Powers of Inquiry: Using Image Analysis to Explore Environmental Health Science

    SBC: SCIENCE-APPROACH            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this Phase II Small Business Innovative Research (SBIR) application is to create a series of educational materials for the National Institute of Environmental Health Sciences (NIEHS) entitled Powers of Inquiry: Using Image Analysis to Explore Environmental Health Science. The ten lessons to be published by the project will employ four advanced techn ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
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