Award Data

To defeat OP nerve agents, we must match both their potency and access to the synaptic cleft. Unfortunately, the most potent organophosphate antidotes cannot access neurons from the systemic circulation. Phosphotriesterase (PTE) enzyme mutants are too large, and small, cationic oximes are too charged to cross the blood-brain-barrier or blood-nerve-barrier in appreciable quantities. State-of-the-ar ...

Low level meteorological data over the world’s oceans is hard to collect, due to the cost and difficulty of sensor emplacement. Crewed aircraft are deployed when major weather events arise, but between those major weather events, in-situ data sources are very limited. Uncrewed aircraft systems (UAS) present a unique opportunity to inexpensively collect meteorological data from remote areas, but ...

Prescribed burns are a critical aspect of land management, but they require vegetation data that is hard to obtain at high resolution and on the timescale required. Our autonomous UAV collects critical fire modeling variables through subcanopy flight, enabling rapid surveys for faster and safer burn planning. In Phase I, we proved the feasibility of mapping live fuel moisture content (LFMC) with s ...

The purpose of the continuation of this Direct-to-Phase II effort is to develop a field-expedient, antimicrobial, hydration-providing wound dressing for acute care of large burn wounds.

In response to DHA202-002, SunFire Biotechnologies (SFB) proposed to develop a 2-fold multiplexed serum bactericidal assay (mSBA) for Shigella antibodies and to demonstrate its operational feasibility.  With that Phase I funding, SFB developed a 4-fold mSBA, based on antibiotic resistance, which allows the simultaneous testing of functional antibodies against S. flexneri serotypes 2a, 3a, and 6, ...

The Transportable Blood Storage (TBS) system is designed to transport fresh whole blood and vaccines farther and more reliably than currently available. A prototype will demonstrate the feasibility of a stackable, portable, active refrigeration unit capable of holding up to 40 units of blood without the need for any additional appliances or ice packs. Concept evaluations will be completed with 720 ...

RF weapons are an emerging battlefield threat. These directed energy weapons are being demonstrated at higher power levels and in smaller, less costly, and more mobile platforms. However, while the defense industry is just now beginning to understand the effects of high-levels of RF energy on electronic systems, through rigorous test and evaluation of instrumented targets and systems, there is sig ...

Virtual human avatars will play a critical role in the next generation of advanced training environments, performance-related physiological modeling, and simulation-based design of protective armor. The overall goal of this project is to design and develop computer software for generating dynamic, mission-relevant avatar movements utilizing USARIEM’s static finite element avatars. During the ini ...

There is tremendous potential to manufacture printed electronics in a more sustainable, flexible, faster, and less costly way. However, innovations in materials have been required for full scale manufacturing. In their successful Phase I, ChemCubed (C3) developed a nanocomposite dielectric with electrical and thermal properties similar to those of FR4 boards currently used in PCB manufacturing. In ...

An approved high-level-disinfection-and-sterilization portable kit is developed that requires the minimum of resources to be used for a mass casualty, resource stressed field hospital scenario. The focus is on sterilization of hinged, narrow channel scope instruments, vital tools when delivering care, which can harbor organic material and bacteria. Power, time,  and staff resources pose challenge ...