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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. ADAPT: Autonomous Data Acquisition and Processing Technologies Payload for Small Unmanned Aircraft Systems

    SBC: KITWARE INC            Topic: 9501

    We propose the continuation of development for the Autonomous Data Acquisition and Processing Technologies (ADAPT) payload. This open source system will manage data collection from onboard sensors, particularly imaging sensors, and provide actionable intelligence by enabling in-flight, real-time application of DNN image processing to support a variety of missions. We will substantially reduce the ...

    SBIR Phase II 2021 Department of CommerceNational Oceanic and Atmospheric Administration
  2. A High-Throughput Blood Esterase Panel Assay

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD10108

    Organophosphorus chemical warfare nerve agents (OP-CWA) are attractive to terrorist groups and rogue states as an inexpensive and accessible technology for chemical warfare. OP-CWA and organophosphate pesticides cause severe neurological symptoms and death by inhibiting the enzyme acetylcholinesterase (AChE); the resulting excess acetylcholine accumulates and overstimulates the human or animal bo ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  3. An automated, high throughput, resin-free device for large scale protein purification

    SBC: CFD RESEARCH CORPORATION            Topic: CBD12102

    Protein manufacturing is of paramount importance to chemical and biological defense applications. Existing protein purification methods primarily rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermeasures to chemical and biological threats. To overcome these limitations, the overall goal of th ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  4. A Next Generation, High-Precision, Field Drug Detection System

    SBC: SensoDX II, LLC            Topic: A16AT008

    The synthetic opioids fentanyl and carfentanil pose an imminent national security threat, given the ease with which they can be obtained, their low lethal doses, and their potential for weaponized use. The purpose of this agreement is to adapt SensoDx’s high-performance miniaturized diagnostics platform based on a programmable bio-nano-chip, with embedded artificial intelligence, to enable U.S. ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  5. Anion Exchange Resin for Chirality-based Separation of Single-wall Carbon Nanotubes

    SBC: Sepax Technologies, Inc.            Topic: N/A

    Sepax Technologies, Inc. has identified a new type of anoin-exchange resin which separates single-wall carbon nanotubes (SWCNTs) with >80% recovery yield and resolves in a single pass the chiral tubes of (6,5) well from commercial SWCNT starting materials by Chromatography. Improvement and scale up of the targeted resin production will facilitate the separation of chiral nanotubes for the academic ...

    SBIR Phase II 2012 Department of CommerceNational Institute of Standards and Technology
  6. A Novel, Aerodynamics-augmented Continuous Ionization System for Electrostatic Collection of Bioaerosols

    SBC: CFD RESEARCH CORPORATION            Topic: CBD12107

    Safe and efficient ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these limitations, we propose to develop and demonstrate a novel bioaerosol ionization and collectio ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  7. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10103

    Current drug discovery and development efforts are severely limited by expensive animal trials and oversimplified in vitro models. Results obtained from in vitro models are not predictive of in vivo toxicity owing to significant difference from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device that reproduces the physiological ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  8. Austere environment, durable, safe, glass equivalent auto injector container technology

    SBC: SIO2 MEDICAL PRODUCTS INC            Topic: CBD202003

    Autoinjectors are a critical piece of medical countermeasure equipment for the general public and our nation’s warfighters. Autoinjectors are used to deliver injectable drugs at home or in the field. Injectable drugs are typically packaged in traditional glass primary containers that are assembled into the auto-injector. Unfortunately, the glass autoinjector containers in use today are at risk o ...

    SBIR Phase II 2022 Department of DefenseOffice for Chemical and Biological Defense
  9. Autonomous Environmental UAV Survey System for Wildfire Assessments

    SBC: Robotics 88, Inc.            Topic: 92

    Prescribed burns are a critical aspect of land management, but they require vegetation data that is hard to obtain at high resolution and on the timescale required. Our autonomous UAV collects critical fire modeling variables through subcanopy flight, enabling rapid surveys for faster and safer burn planning. In Phase I, we proved the feasibility of mapping live fuel moisture content (LFMC) with s ...

    SBIR Phase II 2023 Department of CommerceNational Oceanic and Atmospheric Administration
  10. Carbon Based Nano-Additives for Chemically and Biologically Protective Polymeric Nanocomposites

    SBC: ATS-MER, LLC            Topic: CBD03304

    The development of carbon-based nano-additive bound polymers with enhanced adsorption capacity and reactivity for the neutralization of chemical and biological warfare agents could cause substantial saving of life during CBWA threats. In the Phase I pr

    SBIR Phase II 2004 Department of DefenseOffice for Chemical and Biological Defense
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