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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. IF Conversion System for High-Bandwidth Multiplexed Sensors Arrays

    SBC: Alphacore, Inc.            Topic: None

    Alphacore will develop an Intermediate Frequency (IF) Conversion System for High-Bandwidth Multiplexed Sensors Arrays for Phase II of NIST's 2018 soliciation for Exploratory Measurement Science Topic 9.04.02.68.The proposing team has already successfully developed and evaluated a prototype board in Phase I.The goal in Phase II is therefore to achieve three primary objectives:1) Optimize the design ...

    SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology
  2. TOPIC 356: FLUOROGENIC ASSAY PLATFORM FOR CIRCULAR RNA DETECTION

    SBC: Lucerna Inc.            Topic: NCI

    Circular RNAscircRNAsare a novel class of modified RNAs that are an abundant component of the epitranscriptomePutative functions of circRNAsinclude miRNA sequestrationRNA binding protein scaffoldingmRNA trappingand protein translation regulationDeregulation in one or more of these roles has been linked to several types of cancerOne well studied circRNAciRSis believed to act as a miRNAsponge and in ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Cardiac Monitor for VA ECMO Pediatric and Neonatal Patients

    SBC: TRANSONIC SYSTEMS, INC.            Topic: NHLBI

    PROJECT SUMMARY ABSTRACT Venoarterial Extracorporeal Membrane OxygenationVA ECMOis a way to provide cardiac and pulmonary support to patients without other alternativesThis form of life support is vital to pediatric and neonatal patientsAs with any life supportthere are serious complications that occurThese complications including bleedingthrombosisand infection become more frequent the longer a p ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Continuing Preclinical Development of PPCM Vaginal Contraceptive MPT to IND

    SBC: Yaso Therapeutics Incorporated            Topic: NICHD

    Women in all economicsocialand cultural circumstances suffer from high rates of unplanned pregnancyalong with a high prevalence and incidence of sexually transmitted diseasesTrends in the United States and lesser developed economies are going in the wrong directionThe availability of a single multipurpose prevention productMPTthat prevents both unplanned pregnancy and one or more of the most preva ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. An Interactive, Patient-Specific Virtual Surgical Planning System for Upper Airway Obstruction Treatments

    SBC: Kitware, Inc.            Topic: NIBIB

    ABSTRACTUpper airway surgery encompasses a group of procedures commonly used to treat upper airway obstructionincluding maxillomandibular advancementsurgery of the soft palatenasal surgerytongue reduction surgeryand correction of tracheal stenosisCurrent diagnosis and the subsequent decision making of these pathologies primarily rely on the clinical examination and objective measures such as acous ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Intratumoral immunotherapy with formulated resiquimod for metastatic melanoma

    SBC: Curebiotech, Inc.            Topic: 102

    PROJECT SUMMARYMalignant melanoma is one of the most aggressive types of skin cancercausing a largemajority of skincancer related deaths worldwideThe combination of antiPDand antiCTLAis FDA approved for metastatic melanoma and shows better efficacy than any single agentaloneUnfortunatelythe incidence of highgrade immunerelated adverse eventsirAEsdue toantiCTLAis approachingThere is a pressing clin ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. A High School Program for Preventing Prescription Drug Abuse

    SBC: NATIONAL HEALTH PROMOTION ASSOCIATES, INC            Topic: NIDA

    ABSTRACT A High School Program for Preventing Prescription Drug Abuse This Fast Track SBIR proposal is designed to address the critical need for an effective primary prevention approach for prescription drug abusePDAan urgent public health crisis in the United StatesDeaths from prescription drug overdoses have more than tripled in the pastyearsand the abuse of prescription opioids has fueled a dra ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Phase II- HazPrep Worker Training- Community Risk Profile

    SBC: Inxsol LLC            Topic: 142

    PROJECT SUMMARY ABSTRACT A workerandapos s personal hazard profilePHPis a function of hazards present and his her exposure level to those hazardsWorkers with an elevated level of risk are those who can be engaged in activities related toor working aroundhazardous materialswaste generationremovalcontainmenttransportationand emergency responseinXsol s Phase I feasibility study verified appeal and ef ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. A Single-Cell Proteomic instrument for Predictive Product Quality Check in Autologous CAR-T Immunotherapies

    SBC: IsoPlexis            Topic: NCI

    While CAR T therapies have advanced in the clinicthere are still two specific issues using these breakthrough therapies for blood cancersDurable responses in patients are only atand Cytokine Release Syndrome occurs inof treated patientsThese limitationsfor a drug that costs as much as $may cost an additional $for treating adverse events leading to caution for many clinical centers to administer th ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Goldmann Contact Tonometry with Optimized Error Correction

    SBC: CATS Tonometer, LLC            Topic: NEI

    Intuor TechnologiesLLCProject Summary Goldmann Contact Tonometry with Optimized Error Correction Intraocular pressureIOPmeasurement is a very important criteria used to assess visual acuity when eye care professionals are diagnosingtreatingand managing potential glaucoma patientsGoldman tonometryGATIOP is recognized as thegold standardbut GAT IOP measurements errors have been identifiedPhase I res ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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