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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 9973 results
  1. Integrated, self-actuated, blood collection and biomarker purification device

    SBC: Tasso, Inc            Topic: SB122003

    Blood-based point-of-care (POC) diagnostics or remote diagnostics that require specialized equipment only available in centralized, commercial laboratories are currently limited by major logistical and technical barriers. Blood collection can be a traumatic, inconvenient, and inconsistent process that is based on decades-old technologies, such as the lancet-puncture, that are not amenable to new P ...

    SBIR Phase II 2014 Department of DefenseDefense Advanced Research Projects Agency
  2. A Clinical Trial of Antimicrobial Skin Substitutes for Treatment of Diabetic Ulce

    SBC: Stratatech Corporation            Topic: NIDDK

    DESCRIPTION (provided by applicant): The goal of this Type 2 Competitive Renewal SBIR application to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is to conduct a phase I/II clinical trial to investigate the safety and earlyefficacy of a novel antimicrobial living human skin substitute for the treatment of a life-threatening complication of diabetes: chronic, nonhea ...

    SBIR Phase II 2011 Department of Health and Human Services
  3. Wide dynamic range x-ray Mixed-Mode Pixel Array Detector

    SBC: Sydor Instruments, LLC            Topic: 09a

    Synchrotron light sources and X-ray free electron lasers are now generating shorter pulses with more intense light than ever before possible. The capabilities of these new sources grant unprecedented access into the workings of the natural world. X-ray detectors, as they currently stand, cannot accommodate the large dynamic range of collected x-rays in modern scattering experiments. This capabilit ...

    SBIR Phase II 2018 Department of Energy
  4. Knowledge Management System for Multilingual Health Content

    SBC: Transcendent International, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The aim of the proposed project is to develop an advanced, web-based knowledge management system for the creation and distribution of multilingual, patient-oriented documents. The system provides a vast library of pre-translated documents and document templates for medical, educational, and administrative materials used in patient-care. System users will be abl ...

    SBIR Phase II 2009 Department of Health and Human Services
  5. Human PSMA MAb Radioimmunotherapy for Prostate Cancer

    SBC: PROGENICS PHARMACEUTICALS, INC.            Topic: N/A

    Prostate cancer is the most common cancer of men in the United States with approximately 189,000 new cases and 30,000 deaths in 2002. Recurrent disease can be controlled temporarily with androgen ablation. However, almost all prostate carcinomas eventuall

    SBIR Phase II 2004 Department of Health and Human Services
  6. Development of PSMA-based recombinant protein vaccines

    SBC: PROGENICS PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Prostate cancer is the most common cancer of men in the United States with approximately 189,000 new cases and 30,000 deaths in 2002. Recurrent disease can be controlled temporarily with androgen ablation. However, alm

    SBIR Phase II 2004 Department of Health and Human Services
  7. Antibody-Biocide Fusions to Control Cryptosporidium

    SBC: IOGENETICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this research is develop therapeutic products for Cryptosporidium parvum which can be made at a scale and cost which are feasible for delivery to large populations of patients or individuals at risk, as may be necessary in countering bioterrorism, or in protecting field-deployed armed forces. Our approach is to develop recombinant neutralizing mon ...

    SBIR Phase II 2006 Department of Health and Human Services
  8. Development and validation of therapy for mucopolysaccharidosis III

    SBC: Phoenix Nest Inc.            Topic: 103

    Project Summary Sanfilippo diseasemucopolysaccharidosis type IIIMPS IIIis a devastating neurodegenerative lysosomal storage disorder of childhood whose pathologic features are neurologicslowing of developmentsevere behavioral problemsprogressive cognitive declinedementiaand decline in motor skills leading to immobilityunresponsivenessand deathWe have focused on MPS IIID caused by a deficiency of a ...

    SBIR Phase II 2018 Department of Health and Human Services
  9. Mobile Fetal Magentocardiography

    SBC: Shared Medical Technology, Inc.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Over 1.1 million conceptuses and fetuses die spontaneously each year, nearly 28,000 after 20 weeks' gestation. 12.5% of all infants are delivered prematurely, and the cost of care for the prematurely born is nearly 27 billion dollars annually. Prenatal assessment is currently dominated by ultrasound-based techniques; however, these are limited in their ability ...

    SBIR Phase II 2010 Department of Health and Human Services
  10. Humanized PRO 140 for CCR5-Targeted Therapy of HIV

    SBC: PROGENICS PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A major goal of HIV-1 research is the development of a new generation of antiretroviral agents that target novel stages of the viral replicative cycle. New agents are needed both to combat the growing incidence of HIV-1 strains that are broadly resistant to existing medications and to reduce the considerable toxicities associated with current therapies. HIV- ...

    SBIR Phase II 2003 Department of Health and Human Services

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