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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Direct Performance Evaluation of Additive Manufacturing Process Plans

    SBC: INTACT SOLUTIONS INC.            Topic: None

    Additive manufacturing is steadily advancing towards fulfilling its promise of customized and on-demand production of functional parts. However, performance of as-manufactured parts can differ significantly from the as-designed parts because the as-manufactured geometry differs from the as-designed geometry and the asmanufactured material properties are not known. Attempts to predict performance o ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  2. Nanomachine Device for Semiconductor Process Control Monitoring

    SBC: Xallent LLC            Topic: None

    Conventional characterization and test methods are increasingly ineffective when applied to structures less than 100 nanometers, causing challenges across R&D, process control and failure analysis. An increasing number of subtle defects become prominent drivers of failure as device size and operating margins decrease, e.g., processing anomalies in thin gate oxides, substrate problems related to do ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  3. Continuous Learning for Additive Manufacturing Processes Through Advanced Data Analytics

    SBC: Senvol LLC            Topic: NA

    Additive manufacturing (AM) is a promising manufacturing technique for end-use parts that can solve challenges for American manufacturers in many industries, e.g. aerospace, defense, automotive, energy, and healthcare. However, despite the potential that AM offers, the rate of AM adoption in industry is very slow. This is because AM suffers from low repeatability and quality consistency issues, wh ...

    SBIR Phase I 2018 Department of CommerceNational Institute of Standards and Technology
  4. A Location-based Weather Threat Tracking and Notification System

    SBC: CFD Research Corporation            Topic: 834

    TECHNICAL ABSTRACT: CFDRC proposes the creation of an innovative location-based threat tracking and notification system to allow users to receive hazardous weather messages from the NWS with their call to action, allow users to receive custom-tailored messages about threats, and visualize relevant weather information within their area. The focus is on a tool that allows this information to be comm ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  5. Novel Circulating RNA-based Markers as Diagnostic Biomarkers of Infectious Diseases

    SBC: CFD Research Corporation            Topic: CBD18A001

    In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  6. Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point ofCare Applications

    SBC: GENECAPTURE            Topic: CBD15C001

    GeneCapture, Inc. is proposing to develop a rapid in vitro diagnostic prototype using our patented molecular-based CAPTURE (ConfirmActive Pathogens Through Unamplified RNA Expression) assay. Based on the results and experience gained in our Phase I STTR contractHDTRA1-16C-0061: Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications, we p ...

    STTR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  7. High Temperature High Resolution in-situ Differential Pressure Sensor

    SBC: Innoveering, LLC            Topic: NA

    Chemical manufacturers require high accuracy/high sensitivity pressure sensors to efficiently monitor the various manufacturing systems and processes in the chemical plant, to ensure any changes proceed in a safe and reliable manner, adhering to expected standards and practices. NIST also has a need for highly accurate pressure measurements, especially determining the thermo-physical properties of ...

    SBIR Phase II 2017 Department of CommerceNational Institute of Standards and Technology
  8. Producing Novel Biosynthetic Therapeutics from Extreme Microbiomes

    SBC: IXPRESSGENES, INC.            Topic: CBD152004

    This project is a unique metagenomic evaluation of under-studied extremophilic microbiome natural products (NPs), with the goal of discovering novel antibiotic biowarfare agent (BWA) countermeasures. A metagenomic biosynthetic gene cluster library from extremophilic sources was created, sequenced, analyzed, and exploited to produce several broad-spectrum antibiotic extracts during the Phase I effo ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
  9. Smartphone Application for Mask Sizing and Projecting Quantitative Fit

    SBC: CFD Research Corporation            Topic: CBD161005

    Typical procedures for respirator masks sizing and protective fit test are time-consuming and user intensive, requiring taking anthropometricmeasurements of the wearer, sampling the wearers breathing zone and the use of specialized tools and equipment. The proposed softwareapp aims to quickly, accurately and automatically perform respirator mask sizing and predict protective fit using only 2D imag ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
  10. Exploiting Natural Products-Based Therapeutics for Aflatoxin Mitigation

    SBC: CFD Research Corporation            Topic: CBD152003

    Aflatoxins B1 (AFB1) are fungal produced mycotoxins that are present in food supplies and are strongly associated with increased risk for thedevelopment of hepatocellular carcinoma. Currently, there are no known countermeasures to selectively mitigate AFB1 toxicity. To meet thischallenge, we successfully validated a Phase I proof-of-concept study to harness the microbiome extracts of scavenging ma ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense

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