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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

Displaying 1 - 10 of 3417 results
  1. Direct Performance Evaluation of Additive Manufacturing Process Plans

    SBC: INTACT SOLUTIONS INC.            Topic: None

    Additive manufacturing is steadily advancing towards fulfilling its promise of customized and on-demand production of functional parts. However, performance of as-manufactured parts can differ significantly from the as-designed parts because the as-manufactured geometry differs from the as-designed geometry and the asmanufactured material properties are not known. Attempts to predict performance o ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  2. Nanomachine Device for Semiconductor Process Control Monitoring

    SBC: Xallent LLC            Topic: None

    Conventional characterization and test methods are increasingly ineffective when applied to structures less than 100 nanometers, causing challenges across R&D, process control and failure analysis. An increasing number of subtle defects become prominent drivers of failure as device size and operating margins decrease, e.g., processing anomalies in thin gate oxides, substrate problems related to do ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  3. Compact Heat Exchanger for High Temperature High Pressure Applications Using Advanced Cermet

    SBC: Comprex, LLC            Topic: N/A

    In this proposal, CompRex, LLC (“CompRex”) seeks to realize a transformational and disruptive advancement in heat exchange technology for high temperature and high pressure applications through 1) the use of advanced metal and ceramic composite material, 2) development of a new simplified manufacturing approach, and 3) optimization of heat exchanger design to maximize the performance benefits ...

    SBIR Phase I 2019 Department of EnergyARPA-E
  4. Compact Heat Exchanger for High Temperature High Pressure Applications Using Advanced Cermet

    SBC: Comprex, LLC            Topic: N/A

    In this proposal, CompRex, LLC (“CompRex”) seeks to realize a transformational and disruptive advancement in heat exchange technology for high temperature and high pressure applications through 1) the use of advanced metal and ceramic composite material, 2) development of a new simplified manufacturing approach, and 3) optimization of heat exchanger design to maximize the performance benefits ...

    SBIR Phase II 2019 Department of EnergyARPA-E
  5. TOPIC 356: FLOUROGENIC ASSAY PLATFORM FOR CIRCULAR RNA DETECTION

    SBC: Lucerna Inc.            Topic: NCI

    Circular RNAs (circRNAs) are a novel class of non-coding RNAs that are an abundant component of the epitranscriptome. Putative functions of circRNAs, include miRNA sequestration, RNA-binding protein scaffolding, mRNA trapping, and protein translation regulation. Deregulation in one or more of these roles has been linked to several types of cancer, including pancreatic cancer, basal cell carcinoma, ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Development and Evaluation of a Simulated Prototype to Dynamically Adjust Ambient Environments to Promote Affective Regulation in Individuals with Autism Spectrum Disorder

    SBC: SpaceFactory, Inc.            Topic: na

    The goal of the Phase I proof-of-concept project is to determine if affective and physiological regulation in individuals with autism spectrum disorders (ASD) can be promoted through dynamic adjustments in the environment. This goal will be addressed through the execution of two objectives: (1) development of an Internet of Things (IoT) prototype digital interface; and (2) evaluation of environmen ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. Development of Novel Broad Spectrum Antimicrobial Corneal Tissue Storage Solutions

    SBC: IFYBER, LLC            Topic: ODCDC

    Endophthalmitis is a severe condition caused by inflammation of the ocular cavity and is a significant complication of corneal transplant proceduresoften being caused by microbial contamination of the donor tissueThe introduction of antibiotics into corneal tissue storage solutions in thes drastically lowered the incidence of bacterial endophthalmitis has drastically decreasedhoweverfungal endopht ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Topic 374: Topical Delivery of Nanoformulated Bioactive Chemopreventive Agent in Skin Cancer

    SBC: VASCULAR VISION PHARMACEUTICAL CO            Topic: NCI

    We plan to evaluate the chemopreventive management of solar ultraviolet (UV) mediated DNA damage by two different Nanoformulation of epigallicatechin-3-gallate (EGCG). The formulations to be assessed under this study include: a) chitosan based formulation of EGCG (nano-EGCG), and b) EGCG containing chitosan based solid lipid nanoparticles (E-Ch-SLNPs). EGCG is well-tested and popular polyphenol in ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Topic 380- QIDS: Using Radiomics to Impact Radiotherapy Treatment Planning- Moonshot

    SBC: HealthMyne, Inc.            Topic: NCI

    HealthMyne proposes developing a Clinical Decision Support tool to be used in the point-of-care workflow for the Radiation Oncologist that uses radiomic features that have evidence-based association to disease course and/or normal organ damage, in order to impact the treatment planning process. Phase 1 will focus on extraction, calculation, and validation of identified radiomic features for lung c ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Topic 341: Open Scalable Software Infrastructure for Metabolomics Data

    SBC: Kitware, Inc.            Topic: NCI

    Metabolomics research has great potential, and researchers are rapidly producing new techniques for analyzing the large quantities of measurement data in order to utilize metabolomic data more effectively, including promising techniques for data integration across multiple modalities of data from mass spectrometry (MS) and nuclear magnetic resonance (NMR). However, this confluence of data growth a ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health

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