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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. An Automated Test Bed for Assessing System-of-System (SoS) Assurance

    SBC: DeVivo AST, Inc.            Topic: 9040177R

    As System-of-Systems (SoS) become more complex, interactions and latent emergent behaviors become difficult to identify and control. Unmanned Autonomous Systems (UAS) are a prime example of SoS that are both critical and difficult to assure. Drawing upon prior work into multi-criteria decision making (MCDM), DeVivo AST has developed TOP Score, a software tool that facilitates the modeling and anal ...

    SBIR Phase I 2011 Department of CommerceNational Institute of Standards and Technology
  2. Technology Transfer of Multimodal Biometric Application Resource Kit (MBARK)

    SBC: Ad Harmony            Topic: N/A

    The technical objective of this project is to develop a prototype of a face recognition application in a cloud computing environment utilizing MBARK as the middleware. The application will have a client piece that will run on a mobile device such as a laptop and a server piece that will run on a higher-performance computing cluster. The specific objectives of this development project can be enumer ...

    SBIR Phase II 2011 Department of CommerceNational Institute of Standards and Technology
  3. Development of a GPU-based High Performance Community Radiative Transfer Model

    SBC: Hyper Sensing, LLC            Topic: 835D

    Computation of the radiative transfer model for a hyperspectral sounder with thousands of spectral channels is very time-consuming. Consequently, operational data assimilation systems can assimilate only a few hundred channels. The radiative transfer model is very suitable for GPU implementation to take advantage of GPU massively parallel computing capability, where radiances at various channels c ...

    SBIR Phase I 2011 Department of CommerceNational Oceanic and Atmospheric Administration
  4. Narrowband Perfect Absorber using Metamaterials

    SBC: Phoebus Optoelectronics LLC            Topic: CBD11102

    We propose a metamaterial-enhanced microbolometer with strong absorption over a narrow band that is dynamically tunable over the 8-10 micron band. A single-layer photonic metamaterial consisting of a thin metal film perforated with a 2-D array of dielectric apertures will be deposited on an amorphous-Silicon layer acting as an absorber and bolometer. The metamaterial, in conjunction with planar di ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  5. Multiplex Microsphere Assay for Botulinum Neutralizing Antibodies

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD11109

    Currently, the accepted standard experimental model for measuring protective efficacy against botulism is the Mouse Lethality Neutralization (MLN) assay. Botulism poisoning is a life threatening condition that is not only a public health concern, but could also be a potential biological weapon. With seven serotypes of botulinum neurotoxins, there is need for an alternative to the MLN assay due t ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  6. Microfluidic High-throughput Platform for Determining Kinetic Constants of Enzyme Variants

    SBC: CFD Research Corporation            Topic: CBD10107

    Current high-throughput platforms rely on labeled substrates that produce detectable spectroscopic signals upon reaction for monitoring enzyme catalytic activity. Add to that the high price tag for these instruments, ranging from several hundred thousand to millions of dollars, and there is a clear need for alternate solutions for a label-free, low-cost, high-throughput enzyme screening platform. ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  7. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD Research Corporation            Topic: CBD10103

    Current drug discovery and development efforts are severely limited by expensive animal trials and oversimplified in vitro models. Results obtained from in vitro models are not predictive of in vivo toxicity owing to significant difference from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device that reproduces the physiological ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  8. A High-Throughput Blood Esterase Panel Assay

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD10108

    Organophosphorus chemical warfare nerve agents (OP-CWA) are attractive to terrorist groups and rogue states as an inexpensive and accessible technology for chemical warfare. OP-CWA and organophosphate pesticides cause severe neurological symptoms and death by inhibiting the enzyme acetylcholinesterase (AChE); the resulting excess acetylcholine accumulates and overstimulates the human or animal bo ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense

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