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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. POC Blood Coagulopathy Monitor

    SBC: CFD Research Corporation            Topic: DHA19A001

    Traumatic injuries account for 30% of all life years lost in the US and is the leading cause of death for people under 46 years of age. Uncontrolled bleeding or hemorrhage constitute 30-40% of trauma related deaths and are considered to be a major cause of preventable deaths. Viscoelastic tests such as thromboelastography and rotational thromboelastometry can monitor the dynamics of clot developme ...

    STTR Phase I 2019 Department of DefenseDefense Health Program
  2. MARS Phase II

    SBC: ATC-NY, Inc.            Topic: DHA172004

    System maintenance is time consuming, expensive, and can cause extensive downtime if done improperly. To avoid improper system maintenance, extensive training is often required for existing systems, with additional training required for new capabilities before they can be deployed. This training often slows the deployment of new capabilities. Based on a successful SBIR Phase I prototype, the ATC-N ...

    SBIR Phase II 2019 Department of DefenseDefense Health Program
  3. Caring for the Caregiver: A Theory-Driven Mobile Intervention to Promote Caregiver Well-Being

    SBC: Pro-Change Behavior Systems Inc            Topic: NIA

    Overmillion Americans are currently providing unpaid care to a family memberrelativeor friend with Alzheimer s disease or related dementiaWhile caregiving can be a positive experience that brings meaning and an increased sense of purposeit can also take a tollNearlyof Alzheimer s and dementia caregivers rate their emotional distress as high or very highand as many assuffer from depressionCaregiver ...

    SBIR Phase I 2018 Department of Health and Human Services
  4. Enhanced Treatment Management of Opioid-Dependence in an Office-Based Setting

    SBC: MedicaSafe Inc            Topic: NIDA

    PROJECT SUMMARY ABSTRACT Opioid use disorder is the leading cause of accidental death in the USwith overlethal drug overdoses inSAMHSA estimates thatmillion Americans misuse prescription opioids for non medical purposes annuallyPublic health officials and policymakers have acknowledged the urgent need for innovative approaches to the treatment of those with opioid use disorderin spite of thisthe a ...

    SBIR Phase II 2018 Department of Health and Human Services
  5. Automated Assessment of Leptomeningeal Collaterals on CT Angiograms

    SBC: Kitware, Inc.            Topic: 108

    AbstractThe primary goal of this study is to develop an automated scoring system of leptomeningeal collaterals based on CT angiographyCTAas a quantitative assessment of acute ischemic strokeLeptomeningeal collaterals provide an alternate path of blood flow in the setting of a proximal vessel occlusionThe presence and effectiveness of leptomeningeal collateralsi ecollateral statusvaries significant ...

    STTR Phase II 2018 Department of Health and Human Services
  6. Tau oligomer platform validation using lead series candidate in htau mice

    SBC: Oligomerix, Inc.            Topic: NIA

    TITLETau oligomer platform validation using lead series candidate in htau mice PROJECT SUMMARYSBIR Funding OpportunityAdvancing Research on Alzheimerandapos s DiseaseADand Alzheimerandapos s Disease Related DementiasADRDRRPASThe long term goal of this program is to develop a disease modifyingsmall molecule drug for Alzheimer s diseaseADand related tauopathiesThere is a critical unmet need for a di ...

    SBIR Phase II 2018 Department of Health and Human Services
  7. Aging Heart Modeling with Progeria iPSCs

    SBC: INVIVOSCIENCES, INC.            Topic: NIA

    Project Summary Abstract The United States has the largestmillion inaging populationandgtyears of ageamong developed countries and will reachmillion byHeart failureHFis becoming an epidemic among increasing population of aging AmericansMedical costs of HF are projected to be $billionHF patients are classified by its ejection fractionEFreducedpreservedintermediateWhile various treatment options inc ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Gene and Stem Cell-Based Treatment for Tendinopathy

    SBC: NEW YORK R&D CENTER FOR TRANSLATIONAL MEDICINE AND THERAPEUTICS, INC.            Topic: R

    Project SummaryTendinopathy is a common chronic tendon disorder that affectsof individuals overyears oldIt is characterized by painswellingloss of functionand impaired performanceThere is currently no cure for tendinopathySpontaneous repair or treatment typically leads to scar formationresulting in a weakened tissue with reduced function and mechanical properties that may ultimately rupture with f ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. Scale-up and Synthesis of a Tau Oligomer Inhibitor to initiate IND enabling studies for AD and ADRD

    SBC: Oligomerix, Inc.            Topic: NIA

    PROJECT SUMMARYSBIR RRFast Track ApplicationFOA NumberPASThe long term goal of this program is to develop a disease modifyingsmall molecule drug for Alzheimer s diseaseADand AD related dementiasADRDwith tau pathologyThere is a critical unmet need for a disease modifying drugDMDfor ADChronic treatment strategies require safeeffectiveand economically feasible approaches such as small molecule drugsT ...

    SBIR Phase I 2018 Department of Health and Human Services
  10. Development and validation of therapy for mucopolysaccharidosis III

    SBC: Phoenix Nest Inc.            Topic: 103

    Project Summary Sanfilippo diseasemucopolysaccharidosis type IIIMPS IIIis a devastating neurodegenerative lysosomal storage disorder of childhood whose pathologic features are neurologicslowing of developmentsevere behavioral problemsprogressive cognitive declinedementiaand decline in motor skills leading to immobilityunresponsivenessand deathWe have focused on MPS IIID caused by a deficiency of a ...

    SBIR Phase II 2018 Department of Health and Human Services

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