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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Compact and Portable Remote Monitoring System for Vital Signs with Integrated Photonics

    SBC: CFD RESEARCH CORPORATION            Topic: DHA232002

    Measurement of vital signs (VS) is essential to assess the condition of human body. VS includes body temperature (Tc), heart (pulse) rate (HR), respiration rate (RR) and blood pressure (BP). VS are useful in detecting medical problems. Typically VS measurement and monitoring takes place in a controlled setting like hospital, clinic or home using bulky contact based machines. In order to monitor VS ...

    SBIR Phase I 2023 Department of DefenseDefense Health Agency
  2. TORAS: Temperature-based Operational Readiness

    SBC: NOU SYSTEMS INC            Topic: DHA231001

    Accurate core temperature measurement is critical for safe assessment of warfighter operational readiness since it is a parameter strongly associated with environmental temperature-related injuries and exertional heat exhaustion of thermally burdened soldiers. Yet, this variable is still incredibly challenging to measure accurately, reliably, noninvasively, and cost-effectively. Because of this, i ...

    SBIR Phase I 2023 Department of DefenseDefense Health Agency
  3. Portable Phage Preparation Technology for Field Application

    SBC: CFD RESEARCH CORPORATION            Topic: A20BT023

    Bacteriophages (phages) are becoming important therapeutic candidates against multidrug resistant (MDR) bacterial infections. There is a need to isolate and concentrate phages collected from the field to enhance specimen storage stability for long-distance transport to specialized laboratories for subsequent analysis. Environmental phage preparation requires expensive, bulky instrumentation and in ...

    STTR Phase II 2023 Department of DefenseDefense Health Agency
  4. Dissolvable Materials for Photochemical Tissue Bonding

    SBC: Saxon Glass Technologies, Inc.            Topic: DHA21C001

    This PHASE II two-year proposal is designed to expand upon the knowledge gained already in the PHASE I research regarding the development of rapid bioresorbable glasses to bring us to the making of prototype stents which would be ready for testing in animals and humans. Motivated by the success of PHASE I research, wherein several bioresorbable glasses in the Na2O-K2O-CaO-B2O3-P2O5 have been devel ...

    STTR Phase II 2023 Department of DefenseDefense Health Agency
  5. Flexible Microfluidic Process Technology for Biopharmaceutical Purification of Bacteriophages

    SBC: CFD RESEARCH CORPORATION            Topic: DHA21C002

    Multidrug resistant (MDR) bacterial wound infections remain a persistent challenge for front-line military medical providers in prolonged care treatment. Bacteriophage (phage) therapeutics have demonstrated preclinical and clinical efficacy against ESKAPEE infections. Phage production however remains a challenge to remove common pyrogen contaminants from phage products, including endotoxins (lipop ...

    STTR Phase II 2023 Department of DefenseDefense Health Agency
  6. N3: Negative, Nerve-Targeted Nanocarriers

    SBC: NOU SYSTEMS INC            Topic: DHA213007

    To defeat OP nerve agents, we must match both their potency and access to the synaptic cleft. Unfortunately, the most potent organophosphate antidotes cannot access neurons from the systemic circulation. Phosphotriesterase (PTE) enzyme mutants are too large, and small, cationic oximes are too charged to cross the blood-brain-barrier or blood-nerve-barrier in appreciable quantities. State-of-the-ar ...

    SBIR Phase II 2023 Department of DefenseDefense Health Agency
  7. Wearable Radio Frequency Weapon Exposure Detector

    SBC: ENGENIUSMICRO LLC            Topic: DHA211005

    RF weapons are an emerging battlefield threat. These directed energy weapons are being demonstrated at higher power levels and in smaller, less costly, and more mobile platforms. However, while the defense industry is just now beginning to understand the effects of high-levels of RF energy on electronic systems, through rigorous test and evaluation of instrumented targets and systems, there is sig ...

    SBIR Phase II 2022 Department of DefenseDefense Health Agency
  8. Standard-issue Antimicrobial Combat Burn Gauze

    SBC: IFYBER LLC            Topic: DHA201D001

    The purpose of the continuation of this Direct-to-Phase II effort is to develop a field-expedient, antimicrobial, hydration-providing wound dressing for acute care of large burn wounds.

    SBIR Phase II 2022 Department of DefenseDefense Health Agency
  9. Anionic Nanoparticle Carriers for Neuron-targeting of Synthetic and Protein Drugs

    SBC: CFD RESEARCH CORPORATION            Topic: DHA213007

    Nanoparticles (NPs) frequently are selected to deliver therapeutic agents due to their unique properties, which improve systemic delivery. Notably, the properties of NPs are highly tunable and enable cell-specific targeting of their payload in addition to protecting the therapeutic agent from clearance. For example, recent work demonstrated that anionic NPs selectively target neurons. This charge- ...

    SBIR Phase I 2022 Department of DefenseDefense Health Agency
  10. N3: Negative, Nerve-Targeted Nanocarriers

    SBC: NOU SYSTEMS INC            Topic: DHA213007

    To defeat OP nerve agents, we must match both their potency and access to the synaptic cleft. Unfortunately, the most potent organophosphate antidotes cannot access neurons from the systemic circulation. Phosphotriesterase (PTE) enzyme mutants are too large, and small, cationic oximes are too charged to cross the blood-brain-barrier or blood-nerve-barrier in appreciable quantities. State-of-the-ar ...

    SBIR Phase I 2022 Department of DefenseDefense Health Agency
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