Award Data

The broader impact/commercial potential of this project is to significantly reduce the development effort for continuous sensing applications and to enable deploying them in a wide range of battery-constrained sensing devices, including personal mobile devices like smartphones, tablets, and smart watches; wearable health monitoring devices for tracking EKG/EEG and other vital signals; and remote s ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project will be to more effectively treat serious, infectious corneal ulcers by delivering antibiotics directly to the eye?s surface via a novel, biodegradable flexible polymer film. The platform will deliver drug continuously, thereby eliminating the need for hourly eye drops. This product can be ad ...

The broader commercial potential of this Small Business Innovation Research Phase II project is the commercial development of novel materials and processes for the immobilization of enzymes. The project is targeting enzymes as catalysts to be used in the manufacturing of active pharmaceutical intermediates (API). The use of enzyme for the production of pharmaceuticals has the potential to reduce c ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is the development of a platform for the discovery of new anthelmintic (anti-parasite) drugs. Drug resistance is occurring with all anthelmintics currently on the market. Current drug development only introduces new molecules to the existing drug targets. As a result, drug resistance quickly ...

The broader impact/commercial potential of this project is the significant improvement of surgical accuracy, which will dramatically reduce surgical errors, improve outcomes and reduce healthcare costs. In spine surgery alone, there are more than 500,000 procedures every year in the US utilizing implants such as screws. In 4% to 11% of these surgeries, the implant placement is inaccurate. For the ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is to significantly improve the care of cancer patients by providing an integrated platform for clinical data and image analytics to their care providers for better clinical decision making. Tight integration of clinical data with radiology images will enable evidence-based approaches to be u ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project involves advancements in the state-of-the-art in biomedical technology, improvement of the quality of care for intensive care unit (ICU) patients, and a reduction in healthcare costs. The proposed agitation and sedation system will assist in realizing an improved distribution of ICU workload ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project will be the development of a new natural means of treating diseases of fruit orchards and crops as an alternative to antibiotic use. Over 90% of the world's antibiotic use in agriculture is primarily to control fire blight, a disease that kills fruit trees. Fire blight has emerged as the most ...

The broader impact/commercial potential of this project is to develop a novel platform technology: a high-torque electrostatic motor (EM). This readily scalable platform machine technology can provide any desired torque or power rating necessary along with increased energy accessibility and reduced energy/operating costs compared to traditional steel-copper-magnet based motors. Instead of using pe ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is to develop a new microscope that integrates biodynamic imaging with conventional phase contrast microscopy for use in drug development and other research applications. Accurately capturing the signatures of three-dimensional biological systems provides more realistic measures of drug effic ...