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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Calibrated Methods for Quantitative PET/CT Imaging Phase II

    SBC: Kitware, Inc.            Topic: 102

    DESCRIPTION provided by applicant The overall goal of this Phase II STTR proposal is to develop a PET CT imaging tool that will help accelerate the development of effective cancer therapies by improving the utility of oncology trials using PET imaging The growing cost time and complexity of clinical trials are driving patient and pharmaceutical company demand for more objective efficient a ...

    STTR Phase II 2015 Department of Health and Human Services
  2. Multimodality Image-Based Assessment System for Traumatic Brain Injury

    SBC: Kitware, Inc.            Topic: 101

    DESCRIPTION provided by applicant Nearly million Americans suffer traumatic brain injury TBI annually which constitutes a significant US medical health concern Although neuroimaging plays an important role in pathology localization and surgical planning TBI clinical care does not currently take full advantage of neuroimaging computational technology We propose to develop validate a ...

    SBIR Phase II 2015 Department of Health and Human Services
  3. Neuroimaging tools for presurgical brain mapping

    SBC: PRISM CLINICAL IMAGING, INC.            Topic: 102

    DESCRIPTION provided by applicant The goal of this project is to develop functional magnetic resonance imaging fMRI tools to assist the diagnosis and treatment of human patients with a brain tumor or other operable pathology The specific focus of this proposal is to produce a practical clinic ready suite of MR imaging methods analyses and display tools to solve the number one impediment to ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Quantitative Ultrasound Analysis of Vascular Morphology for Cancer Assessment

    SBC: Kitware, Inc.            Topic: 102

    DESCRIPTION provided by applicant There are several features of ultrasound imaging that make it attractive to clinicians and preclinical researchers including its relatively low cost rel time imaging capability safety and portability For example ultrasound imaging is widely used for anatomical imaging and blood flow measurements in the heart and large vessels Ultrasound however is typi ...

    SBIR Phase II 2015 Department of Health and Human Services
  5. Advanced virtual simulator for fundamentals of laparoscopic surgery training and credentialing

    SBC: Kitware, Inc.            Topic: NIBIB

    DESCRIPTION provided by applicant Surgical simulators are powerful tools that assist in providing advanced training for complex procedures and objective skills assessment They accelerate the training of residents without a penalty in morbidity and mortality while improving skills where patient outcome clearly correlates with surgical experience Fundamentals of laparoscopic surgery FLS is a ...

    SBIR Phase II 2015 Department of Health and Human Services
  6. Glycoconjugate therapeutic peptides for improved treatment of human diseases

    SBC: GLYCOBIA, INC.            Topic: 300

    DESCRIPTION provided by applicant Therapeutic peptides are used to treat human diseases ranging from HIV to diabetes and have some of the best features of small molecule and recombinant protein drugs Therapeutic peptides account for $ billion of annual pharmaceutical sales and are part of a growing sector of the biopharmaceutical market Unfortunately therapeutic peptides suffer from poor s ...

    SBIR Phase II 2015 Department of Health and Human Services
  7. A Data driven Approach to Improve Nursing Workflow and Patient centered Care

    SBC: Transcendent International, LLC            Topic: 102

    DESCRIPTION provided by applicant Patient centered care recognizes patientsandapos desires opinions and preferences as equal in importance to those of healthcare professionals and emphasizes the need to educate and empower patients to play an active role in their care The achievement of patient centered care is associated with increased patient and provider satisfaction improved health ou ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Progressive Model Generation for Adaptive Resilient System Software

    SBC: Grammatech, Inc.            Topic: N13AT014

    Software provides critical functionality to the DoD, as well as to the communications, banking, and logistics industries we rely on. Runtime monitoring is now routinely applied to quickly identify and limit attacks. However, monitors have difficulty distinguishing good behavior from bad because intended application behavior varies widely. This proposal describes SMAC (Scenario-based Modeling & Che ...

    STTR Phase II 2015 Department of DefenseNavy
  9. Clinical Translation of an Anti-Metastatic Antibody for Breast Cancer Therapy

    SBC: FOR-ROBIN, INC.            Topic: 102

    DESCRIPTION provided by applicant Translational studies are proposed to support the continued development of the JAA F antibody based therapy to address the critical need for a safe and effective treatment for metastatic breast cancer including triple negative breast cancers Building on the success of our Phase I project the overarching objectives of the Phase II application are to advanc ...

    STTR Phase II 2015 Department of Health and Human Services
  10. Preclinical Efficacy And Safety Evaluation Of Graphene Nanoparticle-based Magnetic Resonance Imaging Contrast Agent For Diagnosis of Renal Failure

    SBC: Theragnostic Technologies Inc.            Topic: 400

    DESCRIPTION provided by applicant This SBIR phase project focuses on preclinical investigational new drug IND enabling studies of a novel high performance carbon nanostructure based magnetic resonance imaging MRI contrast agent CA to be used to diagnose and monitor patients with renal failure Every year in the US approximately million people are treated for mild to severe renal fa ...

    SBIR Phase II 2015 Department of Health and Human Services

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