Award Data

DESCRIPTION provided by applicant The overall goal of this Phase II STTR proposal is to develop a PET CT imaging tool that will help accelerate the development of effective cancer therapies by improving the utility of oncology trials using PET imaging The growing cost time and complexity of clinical trials are driving patient and pharmaceutical company demand for more objective efficient a ...

DESCRIPTION provided by applicant Nearly million Americans suffer traumatic brain injury TBI annually which constitutes a significant US medical health concern Although neuroimaging plays an important role in pathology localization and surgical planning TBI clinical care does not currently take full advantage of neuroimaging computational technology We propose to develop validate a ...

Software provides critical functionality to the DoD, as well as to the communications, banking, and logistics industries we rely on. Runtime monitoring is now routinely applied to quickly identify and limit attacks. However, monitors have difficulty distinguishing good behavior from bad because intended application behavior varies widely. This proposal describes SMAC (Scenario-based Modeling & Che ...

DESCRIPTION provided by applicant The goal of this project is to develop functional magnetic resonance imaging fMRI tools to assist the diagnosis and treatment of human patients with a brain tumor or other operable pathology The specific focus of this proposal is to produce a practical clinic ready suite of MR imaging methods analyses and display tools to solve the number one impediment to ...

DESCRIPTION provided by applicant There are several features of ultrasound imaging that make it attractive to clinicians and preclinical researchers including its relatively low cost rel time imaging capability safety and portability For example ultrasound imaging is widely used for anatomical imaging and blood flow measurements in the heart and large vessels Ultrasound however is typi ...

DESCRIPTION provided by applicant Surgical simulators are powerful tools that assist in providing advanced training for complex procedures and objective skills assessment They accelerate the training of residents without a penalty in morbidity and mortality while improving skills where patient outcome clearly correlates with surgical experience Fundamentals of laparoscopic surgery FLS is a ...

DESCRIPTION provided by applicant Therapeutic peptides are used to treat human diseases ranging from HIV to diabetes and have some of the best features of small molecule and recombinant protein drugs Therapeutic peptides account for $ billion of annual pharmaceutical sales and are part of a growing sector of the biopharmaceutical market Unfortunately therapeutic peptides suffer from poor s ...

DESCRIPTION provided by applicant Patient centered care recognizes patientsandapos desires opinions and preferences as equal in importance to those of healthcare professionals and emphasizes the need to educate and empower patients to play an active role in their care The achievement of patient centered care is associated with increased patient and provider satisfaction improved health ou ...

DESCRIPTION provided by applicant Translational studies are proposed to support the continued development of the JAA F antibody based therapy to address the critical need for a safe and effective treatment for metastatic breast cancer including triple negative breast cancers Building on the success of our Phase I project the overarching objectives of the Phase II application are to advanc ...

DESCRIPTION provided by applicant This SBIR phase project focuses on preclinical investigational new drug IND enabling studies of a novel high performance carbon nanostructure based magnetic resonance imaging MRI contrast agent CA to be used to diagnose and monitor patients with renal failure Every year in the US approximately million people are treated for mild to severe renal fa ...