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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Human Ghrelin as an Effective Mitigator of Acute Radiation Injury
SBC: THERASOURCE, LLC Topic: NIAIDDESCRIPTIONprovided by applicantThis SBIR Phase II proposal is intended to further develop human ghrelin as a radiation medical countermeasureMCMto be approved by the FDA in the futureThe risks of nuclear terrorism and nuclear power plant leaks still remain highboth of which can cause acute radiation injury on a large scaleCurrentlythere are limited drugs available to treat acute radiation syndrom ...
SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Targeted Transcranial Electrotherapy to accelerate Stroke Rehabilitation-Exploratory Trial on Aphasia
SBC: SOTERIX MEDICAL INC Topic: 105DESCRIPTIONprovided by applicantTranscranial Direct Current StimulationtDCSwith weak currents is a non invasivelow costand well tolerated technique producing lasting functional changes in the central nervous systemThere is increasing evidence supporting the use of tDCS to improve stroke rehabilitationBehavioral and therapeutic outcomes of tDCS depend on the brain areas being targetedHoweverconvent ...
SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Characterization of a low mutation rate E coli in extended fermentation
SBC: SCARAB GENOMICS, LLC Topic: 200DESCRIPTION provided by applicant Scarab Genomics was founded to improve E coli as an industrial organism by genome engineering These strains have stable genomes since all prophages transposable and IS elements and the error prone repair systems were removed A recA version has always been provided as an option The goal of the Phase I project was to ascertain whether the changes already in ...
SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Active Control of a Scramjet Engine
SBC: Innoveering, LLC Topic: AF15AT19In this effort, Innoveering will integrate and test a closed-loop active control system for scramjet isolator shock system positioning. The approach is to control the fuel flow to the engine to position the shock train leading edge at a specified location in the isolator. The control system includes three basic elements: a shock position sensing system based, a fast response fuel valve that adjust ...
STTR Phase II 2016 Department of DefenseAir Force -
A Phase I Dose escalation Study of Intraperitoneal CYN as Consolidation Immunotherapy in Women with Residual or Recurrent Ovarian Cancer Status after Chemotherapy
SBC: Cynvec LLC Topic: 102DESCRIPTION provided by applicant A description of the problem In many cases of advanced epithelial ovarian cancer EOC the standard treatment of cytoreductive surgery is not technically possible and though of ovarian cancer patients initially respond to platinum based chemotherapy the majority experience recurrence and of patients die within years New therapeutic approaches ...
SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Next-Generation Adenovirus Vaccine
SBC: TECHNOVAX INC Topic: A15051One of the most important infectious diseases affecting the health of military recruits is adenovirus, which causes acute outbreaks of respiratory disease in military facilities incapacitating personnel, burdening hospitals, disrupting military operations and increasing medical costs. We propose to continue the development of a new generation of adenovirus vaccines based on adenovirus-like particl ...
SBIR Phase II 2016 Department of DefenseDefense Health Agency -
IGF OT IGF RandD NANOEMULSION FORMULATION AND IND ENABLING STUDIES OF A NOVEL CENTER STEM CELL CYTOTOXIC AGENTPERIOD OF PERFORMANCE SEPTEMBER JULY
SBC: Targagenix, Inc. Topic: NCIThe proposed studies will create evaluate and validate the formulation dosing pharmacodynamics cytotoxicity efficacy and toxicology of a nanoemulsion of a novel cancer stem cell CSC cytotoxic drug DHA SBT In vitro and in vivo assays using FACS purified CSCs will be used to assess efficacy to kill differentiated tumor cells and CSCs NE DHA SBT will be administered intravenously ...
SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Development of an LXR agonist as first in class therapy for treatment of metastatic melanoma
SBC: RGENIX, INC. Topic: 102Abstract Metastatic melanoma remains incurable for the majority of patients Of the patients diagnosed with Stage IIB IV melanoma annually do not respond to existing treatments and for those that do resistance is a major concern Furthermore survival rates for patients with stage IIA IIIB primary tumors steadily decrease with increasing stage Prevention of metastasis itself woul ...
SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Preclinical Testing of Human Ghrelin and Growth Hormone for Sepsis in the Elderly
SBC: THERASOURCE, LLC Topic: NIAPROJECT DESCRIPTIONThis SBIR Phase II proposal is intended to further develop human ghrelinhGhrand human growth hormonehGHas a combination therapy for elderly patients with sepsis and septic shockIn the USmore than one million people develop sepsis every yearand nearlyof septic deaths occur in patients older thanyears of ageCurrentlyno effective pharmacotherapy exists for the treatment of sepsisOn ...
SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Long-Term Reliable, High-Power Midwave-Infrared Quantum Cascade Lasers
SBC: INTRABAND, LLC Topic: A10AT007Intraband, LLC has invented and demonstrated quantum-cascade-laser (QCL) structures that both suppress carrier leakage and have efficient carrier extraction, so-called step-taper active-region (STA) QCLs. As a result, record-high internal efficiencies have been obtained, which are 30-40 % higher than conventional QCLs. Consequently, these midwave infrared (MWIR) semiconductor lasers have potential ...
SBIR Phase II 2016 Department of DefenseArmy