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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Radiological Source Surveillance With V-RADS Video-Centric Radiatiion Detection

    SBC: ADVANCED FUEL RESEARCH, INC.            Topic: N/A

    Radiological sources are in everyday use in numerous industries. Illicit removal of this material from storage could result in construction of a Radiological Dispersal Device or Dirty Bomb. A pervasive means of securing radiological materials and identifying breaches in security is required. Ideally, existing passive surveillance technology would be used, thereby enabling rapid and cost effective ...

    SBIR Phase I 2007 Department of Homeland Security
  2. Lab-on-a-chip for multiplexed newborn screening of lysosomal storage disorders

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): Newborn screening is currently performed by collecting dried bloodspots from infants and then sending them to a lab for analysis. There is an increasing necessity to screen for a number of disease conditions for which therapies are becoming available. Lysosomal storage diseases alone number greater than 40. There is a need to minimize the blood collecte ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  3. Interfacial Adapters for Improved Cell Delivery to Tissues

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Many human diseases can theoretically be treated by injection of healthy or engineered cells into damaged tissue, where ideally they will engraft and remodel the damaged tissue into healthy tissue. However, numerous obstacles stand in the way of this regenerative technology becoming reality. Perhaps the greatest obstacle is that cells injected into many tissues ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  4. Point of Care Attachment of Multiple Antibiotics onto Metal Implants

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Infection surrounding metal implants is a common and sometimes devastating cause of implant failure in a number of fields including oral, craniomaxillofacial (CMF), orthopedic, and cardiovascular surgery. These infections, which arise from the establishment of biofilms on device surfaces, not only necessitate new surgeries but in themselves present a significan ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  5. Bioactive Peptide Coatings for Synthetic Bone Grafts in Dental Applications

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): According to the National Institute of Dental and Craniofacial Research, 86% of adults over 70 years have at least moderate periodontitis and over a quarter have lost their teeth, which has serious repercussion on health and quality of life. Because of bone loss caused by this disease, bone grafting is routinely necessary prior to the placement of dental implan ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  6. Point of Care Adult Stem Cell Isolation

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Approximately 500,000 bone-grafting procedures are performed each year in the United States (Boden, 2002). Autologous iliac crest bone graft continues to be the gold standard because it provides the three essential elements for bone formation: osteoprogenitor cells, an osteoconductive matrix, and osteoinductive molecules. Iliac crest harvest is however associat ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  7. The in vitro hepatitis C virus infection system as a drug discovery tool

    SBC: APATH, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Hepatitis C virus (HCV) infection is a major cause of liver disease throughout the world. Existing therapies are suboptimal and the search for alternative therapies is imperative. Recent years have seen a tremendous increase in efforts to identify more effective therapies against HCV. These efforts have been greatly facilitated by sub-genomic HCV replicon syste ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  8. Preclinical Validation of Human Apyrase in Stroke Models

    SBC: APT THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Human apyrase represents a highly promising therapy for acute ischemic stroke which is a leading cause of death and disability with almost no effective therapy for most patients. This enzyme strongly inhibits platelet activation and aggregation with modest bleeding risk. Using a protein informatics approach, we have successfully engineered a human apyrase, APT1 ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  9. Apyrase to Treat Ischemia/Reperfusion Injury during Lung Transplantation

    SBC: APT THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Human apyrase represents a highly promising therapy to reduce ischemia/reperfusion injury which occurs in10-20% of lung transplant recipients as the consequence of unavoidable processes of procurement, preservation and restoring blood flow. This clinical condition, recently termed primary graft dysfunction, remains an important problem after lung transplantatio ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  10. Developing and Using Sheepshead Minnow Microarrays for Ecotoxicology

    SBC: EcoArray, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Microarrays are a powerful way to measure the impact of contaminants in the environment, and sheepshead minnows (Cyprinodon variegatus) are the most commonly used species in salt water environmental testing. In this proposal, we explain how we will develop and validate a large microarray (5,000+ genes) in sheepshead minnows. We will conduct a number of short an ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
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