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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Novel on-dose authentication to enhance pharmaceutical supply chain security

    SBC: CERTIRX CORPORATION            Topic: FDA

    DESCRIPTION (provided by applicant): The counterfeit drug business originated with lifestyle drugs, such as the erectile dysfunction drug. Now, however, counterfeits in almost any therapeutic category may be purchased by Americans through internet pharmacies. In fact, the Pharmaceutical Safety Institute found in 2010 that counterfeits in the metabolic disease category grew fastest (2), with the tr ...

    SBIR Phase I 2012 Department of Health and Human Services
  2. Responsible Drinking: Internet-based, Interactive Computer Tailored Intervention

    SBC: Pro-Change Behavior Systems Inc            Topic: NIAAA

    DESCRIPTION (provided by applicant): Excessive alcohol use is associated with a range of serious and costly health, social, and economic consequences at the individual and societal level. This program of research serves as a venue by which to produce and test an innovative, science-based, and cost-effective means to intervene in a private, convenient, and individualized way with employed adults wh ...

    SBIR Phase II 2012 Department of Health and Human Services
  3. Oral transmucosal drug delivery system for naltrexone

    SBC: BIONEX PHARMACEUTICALS LLC            Topic: NIAAA

    DESCRIPTION (provided by applicant): The proposed SBIR Phase II project aims at developing a new drug product, the naltrexone orally dissolving film (ODF), for treatment of alcohol dependence. The naltrexone ODF is a small, thin, and flexible film, containing naltrexone hydrochloride and other excipients. It is applied intra-orally and adheres to the oral mucosa to affect a rapid onset of action d ...

    SBIR Phase II 2012 Department of Health and Human Services
  4. Arm Motor Rehabilitation, Entertainment and Cognition System for the Elderly

    SBC: Bright Cloud International Corp            Topic: NIA

    DESCRIPTION (provided by applicant): It is hypothesized that the use robotic rehabilitation tables coupled with virtual reality games with elderly stroke survivors residents in skilled nursin facilities (SNFs) will: 1) improve and maintain upper extremityuni-manual and bimanual function, reach, strength and ADL independence; 2) improve and maintain cognition (memory, focus, problem solving); and ...

    SBIR Phase II 2012 Department of Health and Human Services
  5. Therapeutic Inhibition of MIF in Rheumatoid Arthritis

    SBC: L2 DIAGNOSTICS, LLC            Topic: NIAMS

    DESCRIPTION (provided by applicant): The long-term product goal of this project is a small molecule therapeutic to treat rheumatoid arthritis (RA), which acts by reducing the inflammatory response triggered by the pro-inflammatory cytokine macrophage migration inhibitory factor (MIF). Since MIF is an upstream regulator of the inflammatory cascade, small molecule therapeutics targeting MIF activity ...

    SBIR Phase II 2012 Department of Health and Human Services
  6. Protein Therapeutics for Muscular Dystrophy

    SBC: TRIM-EDICINE, INC.            Topic: NIAMS

    DESCRIPTION (provided by applicant): SBIR 1R43AR060019 Phase II application: Protein Therapeutics for Muscular Dystrophy Principal Investigator: Takizawa, Norio Project Summary: This application requests for a Phase II project for our initial SBIR grant addressing the use of a novel protein therapeutic agent, MG53, for the treatment of muscular dystrophy (1R43AR060019). Our Phase I studi ...

    SBIR Phase II 2012 Department of Health and Human Services
  7. A Needle Guidance System for Hepatic Tumor Ablation That Fuses Real-Time Ultrasou

    SBC: INNEROPTIC TECHNOLOGY INC            Topic: NCI

    DESCRIPTION (provided by applicant): We propose to develop an operating-room-ready system for needle guidance in soft tissue, which fuses intra- operative ultrasound and pre-operative X-ray computed tomography (CT) data by combining two novel technologies:1) a radically different way of visualizing and interacting with the fused ultrasound and CT images, which we call Spotlight ; and 2) an innova ...

    SBIR Phase II 2012 Department of Health and Human Services
  8. Melanocortin Ligands in Disease Cachexia

    SBC: TENSIVE CONTROLS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Cachexia-anorexia syndrome is a life-threatening aspect to many diseases, in particular many forms of cancer or therapies for cancer. The obvious symptoms of this disease include lack of appetite, and a loss of lean body mass disproportionate to the reduction in caloric intake. However, the less obvious effects include multi-organ failure, due to high metabolic ...

    SBIR Phase II 2012 Department of Health and Human Services
  9. Computerized Stage-Matched Intervention for Juvenile Offenders

    SBC: Pro-Change Behavior Systems Inc            Topic: NIDA

    DESCRIPTION (provided by applicant): Juvenile crime imposes enormous costs on victims, on society, and on juvenile offenders themselves. However, research assessing the efficacy of interventions for young offenders show, on average, only small effects on recidivism, substance abuse, and other behavioral outcomes. A major problem with existing interventions is that they tend to neglect individual d ...

    SBIR Phase II 2012 Department of Health and Human Services
  10. Off-the-shelf Dental Regeneration Technologies

    SBC: INNOVATIVE ELEMENTS, LLC            Topic: NIDCR

    DESCRIPTION (provided by applicant): Dentin forms the bulk of the tooth and is covered by enamel in the crown of the tooth and cementum in the root. When dental caries breaks down enamel and involves the dentin, the patient experiences pain and thermal sensitivity. The acute phase of dental pulp infection is typically associated with excruciating pain, and if not properly managed, can lead to per ...

    SBIR Phase II 2012 Department of Health and Human Services

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