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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. DR?1-MOG as a Next-Generation Immunotherapy for Methamphetamine Use Disorder

    SBC: VIROGENOMICS BIODEVELOPMENT INC            Topic: R41

    Methamphetamine use disorder is associated with damage to regions of the brain that control cognitive and psychiatric functionOne third to one half of adults with methamphetamine use disorder experience cognitive impairments and other psychiatric symptoms that significantly impact treatment outcomesincreased relapse and lower treatment retention ratesMounting evidence demonstrates how immune facto ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a lead cyclic-PDZ-Enhancer drug for Anxiety and Depression

    SBC: Aingeal, LLC            Topic: 101

    Major depressive disorder is a debilitating mood disorder that affects ~7% of US adults in their lifetime, costing the U.S. economy more than $200 billion a year. Drugs that increase monoaminergic signaling are the mainstay of depression therapy, but have a delayed onset of action and are only effective in about 50% of affected patients. Aberrant brain-derived neurotrophic factor (BDNF) signaling ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Novel High-Resolution Scintillation X-ray Detectors for Digital Dentistry

    SBC: NGS Detectors LLC            Topic: NIDCR

    Project SummaryNovel High Resolution Scintillation X ray Detectors for Digital Dentistry The transition from traditional film to digital X ray detectors has resulted in significant improvements across many areas for dental X ray imaging ranging from decreased wait timesimproved logistics and even lower radiation dose ratesOne significant drawback remains with digital X ray imaging howeverwhich is ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Small UAS compatible Chemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Sensors

    SBC: NEVADA NANOTECH SYSTEMS, INC.            Topic: AF18BT009

    Proposed herein are novel design methodologies to create sensors for chemical, biological, radiological, nuclear and/or explosive (CBRNE) detection aboard a Small Unmanned Aerial System (SUAS), as well as intelligent Bayesian-based plume analysis and source detection algorithms that offer capabilities for the Air Force above and beyond the state of the art. The assembled technical team of experts ...

    STTR Phase I 2019 Department of DefenseAir Force
  5. SatMod: Bayesian Inference of Spacecraft Geometry and Pose

    SBC: VISION SYSTEMS INC            Topic: AF17AT007

    Increases in space traffic have caused an ever-growing need to recognize, track, and inspect both known and unknown satellites in-situ. Imagery from ground observation platforms provide a convenient and versatile data source for such characterization but is often limited in both quantity and quality. Rapid and automated 3D reconstruction of satellite models from limited 2D imagery would significan ...

    STTR Phase II 2019 Department of DefenseAir Force
  6. Prediction and Measurement of the Carbon Build-Up in Film-Cooled Rocket Engines

    SBC: SIERRA ENGINEERING, INC.            Topic: AF15AT21

    ABSTRACT: Sierra Engineering Inc. (Sierra) believes that existing chemical kinetic models can be efficiently incorporated into commercial CFD codes to predict the mixing, pyrolysis, soot formation and carbon deposition within film cooled rocket engines. During this Phase I STTR effort we will demonstrate that this analysis capability is practical and that we can generate appropriate model validati ...

    STTR Phase I 2015 Department of DefenseAir Force
  7. Correct-by-Construction Synthesis for Multi-Vehicle Autonomy Missions

    SBC: GALOIS, INC.            Topic: AF14AT06

    ABSTRACT: The kinds of capability advancements we anticipate include scalable support for multi-vehicle scenarios with concurrent executions, co-existence of adversarial and cooperative assets, timing and synchronization constraints, heterogeneous sets of specifications (e.g., prioritization over soft vs. hard constraints), and fault-tolerance. The tool development will focus on an open-source so ...

    STTR Phase I 2015 Department of DefenseAir Force
  8. Development of novel compounds for the treatment of atrial fibrillation

    SBC: Elex Biotech, Inc            Topic: NHLBI

    DESCRIPTION provided by applicant Atrial fibrillation AF is the most prevalent type of cardiac arrhythmia in the developed world affecting million people in the United States alone a number that is expected to double by because of population aging Current pharmacological options are ineffective which may be in part because these drugs fail to target key pathogenic mechanisms Recen ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. StrikeVEMP: Automated Portable Bone-Conducted Force Stimuli for Recording Acceleration-Produced coVEMPs

    SBC: Ear And Skull Base Center, Inc.            Topic: NIDCD

    DESCRIPTION provided by applicant Each year million Americans go to health care providers because of vertigo dizziness or balance problems It is the second most common complaint heard in doctorandapos s offices and will occur in of the nationandapos s population at sometime in their lives From through of US adults aged years and older million Americans had ve ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Preclinical and neuroimmunologic study of RTL1000 for methamphetamine addiction

    SBC: VIROGENOMICS BIODEVELOPMENT INC            Topic: R41

    DESCRIPTION provided by applicant Methamphetamine MA dependence is associated with long term damage to regions of the brain that control cognitive and psychiatric function One third to one half of MA dependent adults experience persistent cognitive and other psychiatric disorders up to three years or longer into remission The neuropsychiatric impairments that persist following abstinence ar ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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