You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Developing Nanopieces, a Platform RNAi Delivery Technology for Treatment of Multiple Diseases

    SBC: Nanode Therapeutics, Inc.            Topic: NCATS

    STTR_Developing Nanopieces 7. Project Summary/Abstract The bottleneck of developing new RNAi (RNA Interference) drugs is the lack of highly efficient and non-toxic RNA delivery to non-liver tissues in vivo. It is especially challenging to deliver negatively-charged nucleic acid into avascular, dense, and negatively-charged matrix in hard-to-reach tissues including joint cartilage. NanoDe Therapeut ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  2. Caduceus Quest: An interactive digital media resource to promote knowledge of reproductive health and STEM

    SBC: RESILIENT GAMES STUDIO, LLC            Topic: 500

    PROJECT ABSTRACT This Phase II STTR project will develop Caduceus Quest, an interactive multimedia resource to promote knowledge and interest in careers in STEM and health. It includes a digital game and a table-top analog game. An initial prototype of the Caduceus Quest digital game was developed and tested over the course of our Phase I project. A multidisciplinary team from Resilient Games Stud ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  3. Therapy and Prophylaxis for Genital Tract Infection

    SBC: THERAPYX, INC.            Topic: NIAID

    PROJECT SUMMARY/ABSTRACT Genital tract infection with Neisseria gonorrhoeae does not induce a state of specific protective immunity and can be acquired repeatedly. Despite public health measures, the disease persists at an unacceptably high frequency; there is no vaccine against it, and resistance even to the latest generations of antibiotics continues to emerge. TherapyX, Inc. is advancing GneX12 ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  4. Multiplexed wireless battery-free sensors for pediatric intensive care units (PICU).

    SBC: WEARIFI, INC.            Topic: NICHD

    Project Summary In the pediatric intensive care unit (PICU) monitoring of hemodynamics and oxygen transport provide critical information needed by care providers for decision making. Patients end up with so many wires, tubes and umbilicals that access to the patient and movement become limited. Furthermore, many of these monitoring techniques are invasive, and for the frailest patients in the PICU ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  5. IL-10NanoCap® for Therapy of Familial Adenomatous Polyposis

    SBC: THERAPYX, INC.            Topic: 300

    Project Summary/Abstract Familial adenomatous polyposis (FAP) is an autosomal dominant genetic disease that leads to the development of hundreds to thousands of adenomas in the rectum and the colon. Current medical management involves endoscopic monitoring, resection of advanced polyps and ultimately colectomy in the second decade of life. The risk of developing colorectal cancer is 100% and chemo ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a urinary biomarker panel and software-based solutions to optimize treatment strategies for Systemic Juvenile Idiopathic Arthritis.

    SBC: Ethos Research & Development LLC            Topic: NIAMS

    Abstract Systemic Juvenile Idiopathic Arthritis (SJIA) is a rare, auto-inflammatory condition characterized by prolonged synovial inflammation that can lead to structural joint damage. Roughly 15-30% of SJIA patients develop a complication called macrophage activation syndrome (MAS), which is caused by excessive activation and proliferation of T cells along with macrophages. Patients with recurren ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  7. Low Burden Wearable Sensor System for Diagnosing Obstructive Sleep Apnea in Older Adults

    SBC: Sibel Inc.            Topic: NHLBI

    1 PROJECT SUMMARY: andgt;50% of adults aged 65+ have a high risk of obstructive sleep2 apnea (OSA), a condition that increases the risk of stroke, heart attack, and death. The3 prevalence of OSA is at least twice as high in older adults compared to younger age4 groups. Despite this increased risk and prevalence, only 8% of older adults at high risk5 of OSA receive evaluation by either in-laborator ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  8. Real-time volumetric specimen imager for 3D intra-operative lumpectomy margin assessment

    SBC: Clarix Imaging Corporation            Topic: 102

    Abstract Clarix Imaging, Corporation (Clarix) is focused on solving one of the largest problems in early stage breast cancer treatment, reoperations for positive margins. About 25% of the andgt;200,000 patients who undergo lumpectomy in the US each year will face this additional procedure because current options for identifying positive margins intraoperatively are insufficient. Currently physicia ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  9. Advanced wireless optogenetics and photometry system for neuroscience research

    SBC: Neurolux, Inc.            Topic: 101

    Project Summary/Abstract Neuroscience research over the last decade has been revolutionized by many technological advancements. Optogenetics and fluorescence imaging represent two distinct, and sometimes complementary tools used in neuroscience research to study the central and peripheral nervous systems in the context of the BRAIN initiative. Advanced interrogations of underlying neural circuits ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  10. A portable ultra-widefield fundus camera for nonmydriatic examination of retinopathy of prematurity

    SBC: Biolight Engineering LLC            Topic: N

    Title: A portable ultra-widefield fundus camera for nonmydriatic examination of retinopathy of prematurity Summary: Prompt screening is an essential step to prevent visual impairment and blindness due to retinopathy of prematurity (ROP). It is known that widefield fundus examination is essential for ROP screening, diagnosis and treatment evaluation. However, existing pediatric fundus cameras have ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government