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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. An Internet application for SMART Recovery

    SBC: BEHAVIOR THERAPY ASSOCIATES, LLP            Topic: NIAAA

    DESCRIPTION (provided by applicant): The objective of this research project is to develop, evaluate, and disseminate an Internet-based (web) application for SMART Recovery: Overcoming Addictions (OA). OA will be based on the four point cognitive-behavioral program for SMART Recovery (www.smartrecovery.org). The goal of the OA program is to help users learn cognitive and behavioral skills to abstai ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  2. Probes for Transient Kinase Complexes

    SBC: Icagen, Inc.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Most cellular processes are regulated by reversible protein phosphorylation, which is controlled by protein kinases and phosphatases. Caldera Pharmaceuticals and MedChem Partners propose to develop new probes for characterizing transient protein complexes. MAPK pathways play important roles in cellular differentiation and survival. MAPKs are serine/threonine pr ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. XRpro Technology for the Detection and Evaluation of Carcinogens

    SBC: Icagen, Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): Caldera Pharmaceuticals will develop quantitative biomarker assays for a set of carcinogens. In Phase I, Caldera will demonstrate the feasibility of using its novel XRpro(R) technology to extract, concentrate, quantify, and characterize carcinogens from biological samples. This will also identify protein adduct biomarkers that are involved in critical carcinoge ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  4. Time-resolved measurements of breath hydrogen sulfide

    SBC: SOUTHWEST SCIENCES INC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Hydrogen sulfide (H2S), once identified exclusively as a pernicious toxic gas, is now recognized as a key participant in a myriad of physiological functions. Activity occurs in a wide variety of systems including periodontal, cardiovascular, neurological, inflammatory, and gastrointestinal. We have selected one of these areas and propose new research for examin ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  5. Power Source Development for Compact Proton Accelerators

    SBC: TPL, INC            Topic: NCI

    DESCRIPTION (provided by applicant): Radiation therapy is one of the primary weapons in the battle against cancer, but even with the advances we have made, there remains significant room for improvement in radiation-based treatment technologies. Proton therapy is now considered the most advanced form of radiation therapy available for cancer treatment, but the size and cost of currently available ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  6. Edutainment Tool for Increasing Compliance with Diabetic Retinopathy Screening an

    SBC: VisionQuest Biomedical Inc            Topic: NEI

    DESCRIPTION (provided by applicant): The purpose of this Phase I grant is to establish the feasibility of effecting a measurable positive change in compliance among diabetics with regards to necessary follow-up screening exams and ophthalmic care through a purpose-made, culturally competent, printed medium traditionally used for entertainment: the fotonovela. We will demonstrate statistically the ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  7. VLP-Based Antibody-Inducing Vaccines for HIV-1

    SBC: ALTRAVAX, INC            Topic: NIAID

    DESCRIPTION (provided by applicant): The HIV-1 epidemic has resulted in ~2.7 million new infections in 2007 for a total of ~33 million people living with HIV/AIDS. Clinical trials have shown that HIV-1 infection cannot be prevented by immunization with monomeric recombinant forms of viral envelope (Env) proteins. However, it is clear that the HIV-1 Env contains epitopes that can induce neutralizin ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  8. Improved Vaccines for Influenza B Virus

    SBC: ALTRAVAX, INC            Topic: NIAID

    DESCRIPTION (provided by applicant): Influenza is a major cause of morbidity and mortality around the world. In the United States, seasonal epidemics of flu occur from late fall to early spring affecting all age groups but with especially high rates of infection in children. Serious illness and death are consequences of influenza infection among the elderly, young children, and individuals with o ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  9. Designing Improved HIV-1 Envelope Proteins as Vaccine Candidates

    SBC: ALTRAVAX, INC            Topic: NIAID

    DESCRIPTION (provided by applicant): The HIV-1 epidemic has resulted in ~2.7 million new infections in 2007 for a total of ~33 million people living with HIV/AIDS. Clinical trials have shown that HIV-1 infection cannot be prevented by immunization with monomeric recombinant forms of viral envelope (Env) proteins. However, it is clear that the HIV-1 Env contains epitopes that can induce neutralizin ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  10. Optical Fluorescence and X-Ray Computed Tomography Scanner for Small Animal In-Vi

    SBC: BIOSCAN, INC.            Topic: NCRR

    DESCRIPTION (provided by applicant): The overall goal of this application is to develop a quantitative in-vivo small animal imaging system for fluorescent reporter probes that fuses fluorescence light emitting computed tomography (FLECT) with X- ray computed tomography (CT). The proposed dual-modality imaging system will not only provide a research tool for better understanding of biological funct ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
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