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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Strong protections, tracking, diversion detection, and deactivation of opioid medications in the hospital and related caregiving settings.

    SBC: Curazel LLC            Topic: NIDA

    Under the Small Business Innovation Research ProgramSBIRPhase I programTopicthe Contractor will develop a comprehensive approach to allow hospitals gain control of their opioid medicationsThe Contractor approach is totrack opioids from the pharmacy to the patienttrack the amount given to the patientand for opioid waste to track it back to the pharmacybetter administer opioids to patients that offe ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Improving Spatiotemporal Precision in Noninvasive Electrical Neuromodulation

    SBC: Brain Electrophysiology Laboratory Company, LLC            Topic: 101

    This application describes the commercialization of the Geodesic Transcranial Electrical NeuromodulationGTENtechnology to achieve noninvasive neuromodulation with improved spatiotemporal precisionThe GTEN system enables both EEG source analysis and configurable electrical neuromodulation with theelectrodes of the Geodesic Sensor NetNow in beta release to selected research customersthe GTEN technol ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. The Effective Parenting Program (EPP): An Integrated Stress Reduction andParenting Intervention for Families of Children with Developmental Disabilities

    SBC: DOUBLE S INSTRUCTIONAL SYSTEMS            Topic: NICHD

    Project Summary!Parents who have children with developmental disabilitiesDDcommonly experience high levels of stress related to child behavior problems and contextual issues related to the childandapos s disability that can have a detrimental effect on their parentingCurrent stress management programs for this population of parents often do not lead to a reduction in childrenandapos s behavior pro ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Noninvasive Functional Cortical Mapping with Innovative tEEG

    SBC: CREmedical Corp            Topic: 106

    PROJECT SUMMARY Resective neurosurgery is essential for treating a range of neurologic conditions such as epilepsy and brain tumorsFor some patientswhose lesion is close to cortical language areaspostoperative expressive or receptive language deficit is a major and feared postoperative complicationMuch effort is devoted to identifying the cortical language regionsand relating such localization to ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. A multivalent, easy-to-use product to mitigate and treat radiation exposure

    SBC: FIBROPLATE, INC            Topic: NIAID

    ABSTRACTThe threat of radiological and nuclear accidents or attacks demands for effective radiation medical countermeasuresMCMable to mitigate and treat the effects of exposure to ionizing radiationsHematopoietic acute radiation syndromeHRASand cutaneous radiation syndromeCRSpose severelife threatening risks to exposed individualsCurrently no effective radio mitigatorto be administered after radia ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. An Online Training Support System to Increase Community Clinic Use of an Evidence-Based Treatment for Opioid and Other Drug Addictions in Emerging Adults

    SBC: Sheidow Consulting, Inc.            Topic: NIDA

    PROJECT SUMMARY ABSTRACT The societal costs of drug addiction are astoundingover $billion annuallyexceeding costs for any other health problemThe opioid epidemicespeciallyis devastatingoverAmerican overdose deaths daily at a cost of $billion per yearEach yearmillion emerging adultsEAsagesuse illicit drugsinEAsand overmillion are in need of treatment for substance use disordersSUDEAs represent the ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Development of Novel Compounds for Treatment of Heart Arrhythmias in CPVT

    SBC: Elex Biotech, Inc            Topic: NHLBI

    PROJECT SUMMARY The goal of this project is to complete the preclinical development of Elex Biotechandapos s novel compounds that target and treat the underlying molecular cause of catecholaminergic polymorphic ventricular tachycardiaCPVTCPVTThere are no FDA approved treatments for CPVTa rare genetic disorder affectingindividualswith typical onset in childrenyears of age and no reported difference ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Immunoassay for early diagnosis of mucormycosis

    SBC: DxDiscovery Incorporated            Topic: NIAID

    Mucormycosis is one of the deadliest of the invasive fungal infectionsMucormycosis occurs most often in patients with hematological malignancies undergoing chemotherapypatients who have received hematopoietic stem cell transplants or patients with diabetes mellitusImproved diagnosis is the most frequently noted unmet need for management of the mucormycosis patientDelays in treatment increase the m ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Developing, Testing and Validating a Wearable Alcohol Biosensor

    SBC: Clinitech, LLC            Topic: 450

    PROJECT SUMMARYThis application for a Phase II SBIR award extends the successful completion of Phase I and represents acollaboration between ClinitechLLC and McLean Hospital Harvard Medical School to continue thedevelopment of a wearable biosensor for detecting alcohol in the interstitial fluid of humansExcessive use ofalcohol accounts for much of the public health burden related to alcohol use di ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. DR?1-MOG as a Next-Generation Immunotherapy for Methamphetamine Use Disorder

    SBC: Virogenomics BioDevelopment Inc            Topic: R41

    Methamphetamine use disorder is associated with damage to regions of the brain that control cognitive and psychiatric functionOne third to one half of adults with methamphetamine use disorder experience cognitive impairments and other psychiatric symptoms that significantly impact treatment outcomesincreased relapse and lower treatment retention ratesMounting evidence demonstrates how immune facto ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health

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