Award Data

DESCRIPTION (provided by applicant): The proposed Phase II research program focuses on the development of a wireless Small Animal Physiological Monitor (SAM). The SAM system will provide the capability to monitor up to 16 laboratory animals (initially rats and mice) simultaneously, with continuous recording, synchronization, and display of physiological data, including heart rate, respiratory rate ...

DESCRIPTION (provided by applicant): Barron Associates, Inc. proposes to develop a TELEpHOne Monitor for the Elderly (TELEHOME), a low-profile, body-worn, wireless personal monitor with built-in speakerphone. Functions provided by the TELEHOME system include: (1) monitoring/alerting for fall events, personal emergencies, activity/inactivity, and wandering; (2) automatic connection of mobile speake ...

DESCRIPTION (provided by applicant): Convergence disorders and refractive amblyopia are among the most common and treatable vision problems seen in general optometric clinical practice. Oce- and home-based vision therapy (OBVT and HBVT, respectively) are standard treatments for such disorders. Recent advances in computerized video therapies that emulate vision therapy exercises performed in the op ...

DESCRIPTION (provided by applicant): Because environmental mercury poses significant challenges to global public health, reducing mercury levels in air, soil, and water is an international priority. Widespread distribution of mercury (Hg) by the atmosphere makes current methods of addressing Hg contamination, such as excavation and replacement of soil, too expensive to be practical given the typic ...

Optimization of generator performance and maximization of output power are difficult to attain in the generation of hydro-power. This is due to the changing water conditions and corresponding changes in the form of available energy. ESL proposes to use self-tuning controls in combination with a suitably chosen and optimized generator driven by hydro-energy and condition it for distribution to then ...

DESCRIPTION (provided by applicant): Many craniofacial surgical procedures involve both functional and aesthetic reconstruction for successful completion. The need for soft tissue fill for additional functionality and contouring is an aspect that can have lower priority during reconstructive craniofacial surgeries. Following the major tissue reconstruction, this secondary phase of the procedure i ...

Multifunctional theranostic nanodevices carrying therapeutic payloads, diagnostic agents, and targeted and controlled drug release functions can simultaneously and effectively diagnose and treat cancers. The targeted delivery of chemotherapeutics to tumors can significantly increase the efficacy of drugs while minimizing the severe side effects associated with the drug itself. The integration of ...

A need exists for advances in non toxic treatments for cover and barrier fabrics. Since polybrominated materials have been banned in many European countries and the production of a number of brominated additives terminated in the U.S. as well, future technologies must focus on non-halogenated treatments. In general, non-halogenated treatments (phosphates and borates) are not durable to aqueous sol ...

DESCRIPTION (provided by applicant): Novel protein-free material for minimally compressive surgical hemostasis (Patrick S. Cottler, P.I.) Excessive blood loss is a risk in any surgery, and hemostasis is problematic in minimally invasive and spinal procedures where direct access to the hemorrhage is difficult and external compression is impractical. Although blood transfusion is an accepted and l ...

DESCRIPTION (provided by applicant): Sepsis and related multiple organ dysfunction are a major cause of mortality and morbidity, responsible for over 215 000 deaths per year in the US. Despite growing understanding of the pathomechanism of sepsis, treatment options are still limited primarily to antibiotics, glucocorticoids, and supportive measures. There is wide consensus that mitochondrial dysfu ...