Award Data

The Phase I project showed that novel urethane-functional (NUF) resins could be produced that were free of isocyanates and very useful for one-component, ambient-cured (OCAC) coatings. Resins for OCAC coatings, which are expected to be valued at $5.7 billion by 2019, are used to produce a variety of coatings including oil-based paints, wood stains, varnishes, and aerosol paints._x000D_ Phase I re ...

The broader impact/commercial potential of this Small Business Technology Transfer Research (STTR) Phase II project stems from addressing the problem of embedded energy in the manufacture of magnesium metal for use in vehicle light-weighting. Improving fuel economy by incorporation of the lightest structural metal, magnesium, does not save on total lifecycle energy consumed if the magnesium was pr ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project lies in the prototyping and scaled demonstration of a high-energy lithium-ion cell for commercialization. This is expected to directly feed into the domestic specialty and defense energy storage markets (aerial and underwater drones, on-person battery) and global consumer device markets while ...

Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

The broader impact and commercial potential of this Small Business Technology Transfer and Research (STTR) project is a method to control invasive or otherwise unwanted trees and shrubs in an ecologically friendly manner with a biodegradable product. This will reduce the quantity of synthetic herbicides and/or synthetic herbicide adjuvants currently applied to control woody plants. This is especia ...

Our goal is to develop a firstin class therapeutic agent that directly blocks the metabolism of fructosea key component in sugarIntake of sugarsucroseand high fructose corn syrupHFCSinduces metabolic syndrome and diabetes in laboratory animals and are strongly associated with obesity and diabetes in humansBoth sucrose and HFCS contain fructosewhich stimulates food intake by inducing leptin resista ...

PROJECT ABSTRACT Short bowel syndromeSBSis a major clinical problem affecting newbornschildren and adultsfor which there is currently no known cureThe disorder results from the functional or anatomic loss of extensive segments of small intestine rendering the intestinal absorptive capacity severely compromisedSBS is clinically defined by malabsorptiondiarrheasteatorrheafluid and electrolyte distur ...

ABSTRACT The goal of this proposal is to develop tumor necrosis factorTNFinhibiting compounds as neuroprotectant drugs for treating Alzheimer s diseaseADCurrent FDA approved AD interventions are symptomatic treatments with limited efficacy which do not affect AD etiology or modify the course of disease progressionThusa critical need exists for a novel AD treatment directed towards AD pathophysiolo ...

During operation of E-2D aircraft, excessive cockpit noise and helmet vibration have resulted in documented cases of aircrew fatigue, hearing loss, and missed radio communications. Preliminary studies have identified that poor vibro-acoustic performance of the HGU-68/P helmet in the frequency range of E-2D operation may be the root cause. Skyward proposes a solution leveraging high-fidelity comput ...

Cornerstone Research Group Inc. (CRG) proposes to provide the Navy with experimentally validated solutions for reducing noise and vibration transmitted through the helmet in the E-2D aircraft, ultimately relieving pilots of harmful vibration and noise. This will be achieved through the development of a finite element model of the HGU-68/P helmet with appropriate loading and boundary conditions to ...