Award Data

In this effort, nGimat will develop the capabilities to produce high-quality optical ceramic nanopowder for DoD applications such as laser and missile weapons and defense systems.Development of such capabilities will require improvements in current man...

DESCRIPTION provided by applicant A Phase II SBIR program of preclinical development is proposed for the development of an active specific immunotherapeutic called Cellariumandquot for treatment of glial cell based cancers Successful completion of this project will confirm therapeutic effect and pre clinical safety of the vaccine in preparation for first in human studies Upon demonstration of ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is intimately tied to the significant increase in transistor density that semiconductors have experienced over the past few decades. This has enabled many technological advances ranging from high performance servers to Internet of Things devices. Still with every advance in chip technology the ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to guide real estate development toward walkable development by forecasting its economic value. In this way, the project will enhance environmental sustainability in cities by creating conditions that promote walking and reduce auto use. Mounting evidence reveals walkability has many social ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project addresses the costly and life-altering occurrence of falls among older adults. One in three adults over the age of 65 fall each year, and 31% of those falls are attributed to environmental hazards such as floor clutter, rugs, poor lighting, and low contrast. Costs associated with falls will re ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to improve outcomes for cardiothoracic surgery patients by ensuring proper post-surgical drainage and allowing for use of small-bore chest tubes. In the United States, approximately 750,000 major cardiothoracic surgeries are performed each year. These patients receive at least one chest tub ...

The broader impact/commercial potential of this project is a breakthrough innovation that will revolutionize preclinical drug testing, provide valuable information for the first-in-human clinical trials, rescue drugs, decrease time to optimize therapies, and reduce the incidence of safety hazards and adverse reactions. Clinical-Trials-on-a-Chip will serve as the pioneering platform for predictive ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project is to establish a bio-based manufacturing process for the production of the commodity chemical 4-hydroxycoumarin (4-HC) in an economical and renewable way. 4-HC is a direct synthetic precursor used to manufacture widely used oral anticoagulants, such as warfarin, acenocoumarol, and phenprocoumon. In a ...

Technological advances have facilitated weapons systems capable of simultaneously supporting multiple missions leading to cost efficiencies and greater operational flexibility.Future systems capable of deploying multiple payloads from a single missile will enable various targets to be attacked with a single launch allowing more efficient use of limited and valuable resources.For such a system to w ...

DESCRIPTION provided by applicant Inhibikase Therapeutics is a clinical stage biopharmaceutical company that has developed a host targeted mechanism of action to treat AIDS related and drug induced progressive multifocal leukoencephalopathy PML PML is a demyelinating disease of the central nervous system and was rarely seen clinically until the era of the HIV epidemic began in the mid s During the ...