Award Data

DESCRIPTION provided by applicant A Phase II SBIR program of preclinical development is proposed for the development of an active specific immunotherapeutic called Cellariumandquot for treatment of glial cell based cancers Successful completion of this project will confirm therapeutic effect and pre clinical safety of the vaccine in preparation for first in human studies Upon demonstration of ...

Technological advances have facilitated weapons systems capable of simultaneously supporting multiple missions leading to cost efficiencies and greater operational flexibility.Future systems capable of deploying multiple payloads from a single missile will enable various targets to be attacked with a single launch allowing more efficient use of limited and valuable resources.For such a system to w ...

Innovative Imaging and Research (I2R) proposes to develop a 21st Century high-speed, color extreme high dynamic range (Color-XHDR) video recording system that will produce calibrated, engineering-grade video to accurately document rocket motor firings, at close range within a test cell, without image saturation. This novel imaging system will include a compact, single camera/single focal plane ar ...

The broader impact/commercial potential of this Small Business Innovation Research Phase II project is to provide the paint and coatings industry with new high-performance, cost-competitive polymer/resin systems that reduce solvent emissions and use of petrochemicals. In addition, these new polymer/resin systems enable one-component, ambient-cure coatings to be produced. This means that highly pro ...

ABSTRACT:A system is proposed to access, collate and process imagery from multiple small satellite constellations. The imagery is fused and registered to a common reference so that exploitation algorithms, such as change detection and event monitoring, are reported with accurate geographic coordinates. The system, called SatTel, is implemented as open source software that is designed to run on the ...

DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

Project Summary Pertussis is rapidly re emerging as a serious public health threat in the United StatesDespite high vaccine coverage nationallyannual reported cases in the U Shave been increasing recentlywith ayear high ofinMoreoverreported cases represent a large underestimate of pertussis infectionsDiagnosis of early pertussiscatarrhal stageprior to paroxysmal coughis particularly challenging be ...

DESCRIPTION provided by applicant This project will develop a commercial product that will enable for the first time realtime tumor tracking during radiotherapy at an attractive price point and with minimal interference with standard clinical practice The key novel technology is an optimized multi source X ray tube with focal spots that is placed below the multi leaf collimator MLC of a r ...

The broader impact/commercial potential of this project is to establish a precedence for remote, real time assessment of the safety and serviceability of infrastructural assets through the development of a self-powered structural health monitoring system. This piezoelectric fatigue fuse (PFF) will enable the establishment of quantifiable metrics to discern the current state of life as well as proj ...

Tinea capitis scalp ringworm is a fungal dermatophyte infection of scalp hair follicles that afflicts of the U S pediatric population Tinea capitis is a major health care disparity because it occurs predominantly among individuals with a disadvantaged socioeconomic background and sub Saharan African descent Diagnosis of tinea capitis is currently dependent on culture and microscopy Both ...