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MANY APPLICATIONS OF ELECTROPHORESIS INVOLVE SEPARATION OF DNA FRAGMENTS NOT ONLY FOR ANALYSIS BUT ALSO FOR SAMPLE ISOLATION AND PURIFICATION. RECOVERING DNA FROM ELECTROPHORETIC GELS AND PURIFYING IT IS AN INITIAL STEP IN PROCEDURES SUCH AS; THE POLYMERASE CHAIN REACTION (PCR), DEVELOPING CLONING LIBRARIES FOR PHYSICAL MAPPING AND DNA SEQUENCING. PRESENT PROCEDURES FOR EXTRACTING DNA FROM A GEL M ...

THE OBJECTIVE OF THIS SBIR PROJECT IS TO DEVELOP A NEW, SOLID STATE IMMUNOSENSOR WITH CAPABILITIES FOR USE IN HOMES,FARMS, FACTORIES AND OFFICES FOR ON-SITE QUANTITATIVE DETERMINATION OF HORMONES, DRUGS AND TOXINS IN BIOLOGICAL FLUIDS SUCH AS PLASMA, SALIVA, AND URINE. THE PRINCIPLE OF DETECTION WILL BE BASED ON AN ENZYME-AMPLIFIED, IMMUNOELECTROCHEMICAL SOLID STATE DETECTOR THAT CAN BE COUPLED TO ...

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STRIATAL TRANSPLANTATION OF NEUROTRANSMITTER CELLS, IMMUNOISOLATED WITHIN A PERMSELECTIVE POLYMER MEMBRANE CAPSULE, REPRESENTS A NOVEL APPROACH TO THE TREATMENT OF PARKINSON'S DISEASE. THE TECHNIQUE HAS HAD PROMISING RESULTS IN SEVERAL RODENT MODELS, AND PRIMATE STUDIES ARE UNDERWAY. THE OVERALL OBJECTIVE OF THIS RESEARCH IS TO COMPLETE THE DEVELOPMENTS NECESSARY FOR WIDESPREAD MEDICAL ACCEPTANCE ...

THE LONG-TERM OBJECTIVE OF THIS RESEARCH IS THE DEVELOPMENT AND INTRODUCTION TO MEDICAL PRACTICE OF AN EFFECTIVE BIOCOMPATIBLE IMPLANTABLE HYBRID ARTIFICIAL ENDOCRINE PANCREAS THAT IS CAPABLE OF SIGNIFICANT IMPROVEMENT IN THE THERAPY OF INSULIN-DEPENDENT DIABETES. THE SPECIFIC AIM OF THIS PROJECT IS TO EXTEND AND MODIFY A PROCESS FOR CELLULAR ENCAPSULATION TO THE ISLETS OF LANGERHANS, USING A CO-E ...

ALONG WITH TREMENDOUS ADVANCES IN THE TECHNOLOGY SUPPORTING GRAPHICAL AND HEADS-UP DISPLAYS COMES A DIZZYING ARRAY OF OPTIONS FOR THE DISPLAY OF COMPLEX STATIC AND DYNAMIC INFORMATION TO PILOTS IN MODERN AIRCRAFT. TO DATE, RESEARCH ON THE EFFECTIVENESS OF GRAPHICAL DISPLAY FORMATS AS AIDS TO DECISION-MAKING AND MONITORING HAS BEEN LARGELY EQUIVOCAL (JARVENPAA AND DICKSON, 1988) (SANDERSON, FLACK, ...

TELE-AUTONOMOUS CONTROL OF MANIPULATOR(S) PRESUPPOSES THE EMPLOYMENT OF SOME TYPE OF PHYSICALLY ACTIVATED OR ACTUATED CONTROLLER AT THE HUMAN INFTERFACE. THE RESEARCH PROPOSED HEREIN ADDRESSES THE DESIGN AND PROTOTYPING OF A SIX DEGREE OF FREEDOM CARTESIAN COORDINATE HAND CONTROLLER. THE DEVICEESSENTIALLY IS AN XYZ STAGE TO WHICH A THREE-ROLL WRIST AND HANDGRIP IS AFFIXED. THE SIX DEGREES OF FREED ...

TO CONSTRUCT AN EMULATION CAPABILITY FOR EXISTING OR PLANNED ROBOTIC COMMAND CENTERS (RCCS) WE PROPOSE TO APPLY TECHNOLOGY DEVELOPED FOR SIMULATION AND CONTROL OF TELEOPERATED SERVICING ROBOTIC SYSTEMS TO THE PROBLEM. AS PART OF A COLLABORATION WITH IN THE CENTER FOR AUTONOMOUS AND MAN-CONTROLLED ROBOTIC AND SENSING SYSTEMS, A NASA SPONSORED CENTER FOR COMMERCIAL DEVELOPMENT OF SPACE AUTOMATION AN ...