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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Novel on-dose authentication to enhance pharmaceutical supply chain security

    SBC: CERTIRX CORPORATION            Topic: FDA

    DESCRIPTION (provided by applicant): The counterfeit drug business originated with lifestyle drugs, such as the erectile dysfunction drug. Now, however, counterfeits in almost any therapeutic category may be purchased by Americans through internet pharmacies. In fact, the Pharmaceutical Safety Institute found in 2010 that counterfeits in the metabolic disease category grew fastest (2), with the tr ...

    SBIR Phase I 2012 Department of Health and Human Services
  2. Responsible Drinking: Internet-based, Interactive Computer Tailored Intervention

    SBC: Pro-Change Behavior Systems Inc            Topic: NIAAA

    DESCRIPTION (provided by applicant): Excessive alcohol use is associated with a range of serious and costly health, social, and economic consequences at the individual and societal level. This program of research serves as a venue by which to produce and test an innovative, science-based, and cost-effective means to intervene in a private, convenient, and individualized way with employed adults wh ...

    SBIR Phase II 2012 Department of Health and Human Services
  3. Picture Me Alcohol Free: Engaging Youth in Community-Based Prevention

    SBC: Prevention Strategies LLC            Topic: NIAAA

    DESCRIPTION (provided by applicant): This application proposes to build on the successful Phase I Picture Me Alcohol Free (PMAF) feasibility pilot study. PMAF is a community-based program designed to train groups of youth to a) represent contributing factors and consequences (e.g., social availability, alcohol-involved crashes) of underage drinking in their communities through a specific photograp ...

    SBIR Phase II 2012 Department of Health and Human Services
  4. Whole-brain fluorescence and brightfield imaging at single-cell level

    SBC: DMetrix, Inc            Topic: NIA

    DESCRIPTION (provided by applicant): The goal of this project is to develop an open and flexible imaging platform capable of rapid, 0.5- 5 m pixel resolution image capture of large-area histology sections (up to 125 mm by 175 mm), in brightfield and by epi-fluorescence optical sectioning. The project involves state-of-the- art instrumentation development coupled with application programming inter ...

    SBIR Phase II 2012 Department of Health and Human Services
  5. A Needle Guidance System for Hepatic Tumor Ablation That Fuses Real-Time Ultrasou

    SBC: INNEROPTIC TECHNOLOGY INC            Topic: NCI

    DESCRIPTION (provided by applicant): We propose to develop an operating-room-ready system for needle guidance in soft tissue, which fuses intra- operative ultrasound and pre-operative X-ray computed tomography (CT) data by combining two novel technologies:1) a radically different way of visualizing and interacting with the fused ultrasound and CT images, which we call Spotlight ; and 2) an innova ...

    SBIR Phase II 2012 Department of Health and Human Services
  6. Melanocortin Ligands in Disease Cachexia

    SBC: TENSIVE CONTROLS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Cachexia-anorexia syndrome is a life-threatening aspect to many diseases, in particular many forms of cancer or therapies for cancer. The obvious symptoms of this disease include lack of appetite, and a loss of lean body mass disproportionate to the reduction in caloric intake. However, the less obvious effects include multi-organ failure, due to high metabolic ...

    SBIR Phase II 2012 Department of Health and Human Services
  7. Computerized Stage-Matched Intervention for Juvenile Offenders

    SBC: Pro-Change Behavior Systems Inc            Topic: NIDA

    DESCRIPTION (provided by applicant): Juvenile crime imposes enormous costs on victims, on society, and on juvenile offenders themselves. However, research assessing the efficacy of interventions for young offenders show, on average, only small effects on recidivism, substance abuse, and other behavioral outcomes. A major problem with existing interventions is that they tend to neglect individual d ...

    SBIR Phase II 2012 Department of Health and Human Services
  8. Targeting Oral Biofilms with 2-Aminoimidazole/Triazole Conjugates

    SBC: AGILE SCIENCES, INC.            Topic: NIDCR

    DESCRIPTION (provided by applicant): Dental caries is one of the most prevalent diseases in the U.S. with 85% of adults and the majority of children having been treated for at least one incidence. While this disease impacts all individuals, it is especially an issue for those of low economic status who have limited access to professional oral care. Dental caries is attributed to the presence of t ...

    SBIR Phase II 2012 Department of Health and Human Services
  9. EpiVax Phase II SBIR: Preclinical studies of Tregitope Delivery and Mechanism of

    SBC: EPIVAX, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): The goal of this Phase II project is to advance the development of novel tolerance-inducing peptides (Tregitopes) to prevent and/or treat Type 1 diabetes (T1D) by optimizing the clinical delivery vehicle and treatment protocol, and by identifying correlates of efficacy in preparation for Phase 1 clinical trials. More than 13,000 children in the U.S. are diagnos ...

    SBIR Phase II 2012 Department of Health and Human Services
  10. Improving Obesity Outcomes Through Interactive Web-Based Clinical Skills Training

    SBC: Clinical Tools, Inc            Topic: NIDDK

    DESCRIPTION (provided by applicant): The dire implications of the adult obesity epidemic grow worse over time. Despite front page coverage and universal agreement that the epidemic in weight gain and secondary disease establishment must be addressed, the problem continues. Intended Impact: We propose to improve outcomes of patients with obesity or at risk for obesity via a PC/mobile web-based prod ...

    SBIR Phase II 2012 Department of Health and Human Services

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